公开(公告)号：US20240240171A1

公开(公告)日：2024-07-18

申请号：US18560380

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Chao WANG ,  Zhenkun LI ,  Long SUN ,  Peng ZHAO ,  Yaoji LIU ,  Haoran WEN ,  Weiye GAO ,  Chaohui ZHANG ,  Cong LIU

IPC: C12N15/10 ,  B01L7/00 ,  G01N21/64 ,  G01N35/00 ,  G01N35/10

CPC classification number: C12N15/1013 ,  B01L7/52 ,  G01N21/6428 ,  G01N35/00732 ,  G01N35/0099 ,  G01N35/1002 ,  G01N35/1079 ,  B01L2200/0647 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/041 ,  B01L2300/0663 ,  B01L2300/1805 ,  B01L2300/1894 ,  G01N2021/6439 ,  G01N2035/00752 ,  G01N2201/08

Abstract: A DNA and RNA nucleic acid co-extraction and detection system includes a nucleic acid extraction system, a sealing, transferring and mixing system, a nucleic acid detection system and a control system, wherein the nucleic acid extraction system, the sealing, transferring and mixing system and the nucleic acid detection system are all connected to the control system; the nucleic acid extraction system comprises a carry basket for loading an extraction reagent strip and a sample tube, a consumable-material supply module, a reagent kit loading module, a barcode scanning device for automatically inputting barcode information, a magnetic absorption incubation device, and an automatic sample addition device for transferring a liquid to a reaction chamber of the extraction reagent strip or a PCR tube and sealing the PCR tube; the sealing and transferring system comprises a PCR transferring device for grabbing and driving a PCR tube to move, and a high-speed mixing device.

公开(公告)号：US20240027347A1

公开(公告)日：2024-01-25

申请号：US18265418

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Chao WANG ,  Peng ZHAO ,  Yaoji LIU ,  Zhenkun LI ,  Yang PAN ,  Long SUN ,  Cong LIU

IPC: G01N21/64 ,  C12N15/10 ,  B01L7/00 ,  G01N35/00 ,  G01N35/10

CPC classification number: G01N21/6428 ,  C12N15/1006 ,  B01L7/52 ,  G01N35/0099 ,  G01N35/1002 ,  B01L2300/1805 ,  B01L2200/16 ,  B01L2300/0672 ,  B01L2200/0647 ,  G01N2035/00356

Abstract: A nucleic acid extraction and fluorescent PCR detection system, comprising: an extraction strip, an extraction strip loading device for loading the extraction strip, a sample holder loading device for loading and unloading samples, an extraction strip transfer gripper for driving the extraction strip to move to a preset position, a nucleic acid extraction device for purifying the samples to obtain nucleic acids, a PCR detection device for performing fluorescent PCR detection on the nucleic acids, and a control device, wherein the extraction strip loading device, the sample holder loading device, the extraction strip transfer gripper, the nucleic acid extraction device and the PCR detection device are all connected to the control device. The problems of relatively poor flexibility and relatively low detection efficiency of a nucleic acid extraction and detection system can be ameliorated, so that a sample detection process is more flexible and convenient.

公开(公告)号：US20240093176A1

公开(公告)日：2024-03-21

申请号：US18038230

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Peng ZHAO ,  Yang PAN ,  Yaoji LIU ,  Chao WANG ,  Cong LIU

IPC: C12N15/10

CPC classification number: C12N15/1003

Abstract: An automatic loading system for an extraction strip includes: an extraction strip for holding several reagents, a first channel, a second channel parallel to and attached to the first channel, a first hand pushing device for pushing the extraction strip to move in the first channel, a second hand pushing device for pushing the extraction strip to move in the second channel, and a transfer device for transferring the extraction strip from the first channel to the second channel. One end of the first channel is a loading inlet of the extraction strip. One end of the second channel is a grabbing position of the extraction strip. The transfer device is arranged at the other ends of the first channel and the second channel. The first hand pushing device and the second hand pushing device can move transversely and move up and down.

公开(公告)号：US20240069052A1

公开(公告)日：2024-02-29

申请号：US18269951

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Chao WANG ,  Peng ZHAO ,  Pengtao WU ,  Yang PAN ,  Yaoji LIU ,  Zhenkun LI ,  Cong LIU

IPC: G01N35/10 ,  B08B3/04 ,  B08B13/00 ,  G01N35/00

CPC classification number: G01N35/1004 ,  B08B3/04 ,  B08B13/00 ,  G01N35/00732

Abstract: A cartridge preprocessing system applied to an automated molecular diagnostics instrument is provided. The cartridge preprocessing system includes a piercing device and a cleaning device. The piercing device includes a drive assembly and a piercing member, and the drive assembly is configured to control the piercing member to alternately move to a piercing station and a cleaning station. The piercing member is configured to pierce a barrier film of a cartridge that moves to the piercing station, and the cleaning device is configured to clean the piercing member that moves to the cleaning station.