公开(公告)号：US20240241143A1

公开(公告)日：2024-07-18

申请号：US18560382

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Chao WANG ,  Peng ZHAO ,  Long SUN ,  Zhenkun LI ,  Weiye GAO ,  Cong LIU

IPC: G01N35/00

CPC classification number: G01N35/0098 ,  G01N35/00584 ,  G01N2035/00376

Abstract: A magnetic attraction incubation mechanism of an automatic molecular diagnostic instrument, includes: a magnetic attraction assembly used for magnetic attraction of a reaction chamber containing a sample liquid and an incubation assembly used for heating the reaction chamber, and further comprising: a driving device for driving the incubation assembly and the magnetic attraction assembly to be alternately close to the reaction chamber, the magnetic attraction assembly and the incubation assembly being both connected to the driving device. Switching of an incubation operation and a magnetic attraction operation can be achieved, and an incubation part and a magnetic attraction part effectively work in conjunction with each other by means of a linkage mechanism, so that the overall structure is effectively simplified, the space is saved, and a detection speed of the sample liquid can further be increased.

公开(公告)号：US20240240171A1

公开(公告)日：2024-07-18

申请号：US18560380

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Chao WANG ,  Zhenkun LI ,  Long SUN ,  Peng ZHAO ,  Yaoji LIU ,  Haoran WEN ,  Weiye GAO ,  Chaohui ZHANG ,  Cong LIU

IPC: C12N15/10 ,  B01L7/00 ,  G01N21/64 ,  G01N35/00 ,  G01N35/10

CPC classification number: C12N15/1013 ,  B01L7/52 ,  G01N21/6428 ,  G01N35/00732 ,  G01N35/0099 ,  G01N35/1002 ,  G01N35/1079 ,  B01L2200/0647 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/041 ,  B01L2300/0663 ,  B01L2300/1805 ,  B01L2300/1894 ,  G01N2021/6439 ,  G01N2035/00752 ,  G01N2201/08

Abstract: A DNA and RNA nucleic acid co-extraction and detection system includes a nucleic acid extraction system, a sealing, transferring and mixing system, a nucleic acid detection system and a control system, wherein the nucleic acid extraction system, the sealing, transferring and mixing system and the nucleic acid detection system are all connected to the control system; the nucleic acid extraction system comprises a carry basket for loading an extraction reagent strip and a sample tube, a consumable-material supply module, a reagent kit loading module, a barcode scanning device for automatically inputting barcode information, a magnetic absorption incubation device, and an automatic sample addition device for transferring a liquid to a reaction chamber of the extraction reagent strip or a PCR tube and sealing the PCR tube; the sealing and transferring system comprises a PCR transferring device for grabbing and driving a PCR tube to move, and a high-speed mixing device.

公开(公告)号：US20250155461A1

公开(公告)日：2025-05-15

申请号：US18725130

申请日：2022-12-23

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Peng ZHAO ,  Can XU ,  Shuaifeng YIN ,  Chao ZHAO ,  Xudong SUN ,  Baojun WU ,  Zhiguang ZHU ,  Jianping HOU ,  Chao WANG ,  Cong LIU

IPC: G01N35/04

Abstract: A conveying track includes a frame, a delivery track is arranged on the frame, and is formed by assembling one or more kinds of H-shaped tracks, T-shaped tracks, L-shaped tracks, U-shaped tracks and I-shaped tracks, and a sample blocking device and/or a diversion device are/is arranged on the delivery track. The conveying track of the present invention has a more flexible track layout, and satisfies the diversified layout requirements of a laboratory delivery system, and thus the installation efficiency of the track is improved.

公开(公告)号：US20240027347A1

公开(公告)日：2024-01-25

申请号：US18265418

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Chao WANG ,  Peng ZHAO ,  Yaoji LIU ,  Zhenkun LI ,  Yang PAN ,  Long SUN ,  Cong LIU

IPC: G01N21/64 ,  C12N15/10 ,  B01L7/00 ,  G01N35/00 ,  G01N35/10

CPC classification number: G01N21/6428 ,  C12N15/1006 ,  B01L7/52 ,  G01N35/0099 ,  G01N35/1002 ,  B01L2300/1805 ,  B01L2200/16 ,  B01L2300/0672 ,  B01L2200/0647 ,  G01N2035/00356

Abstract: A nucleic acid extraction and fluorescent PCR detection system, comprising: an extraction strip, an extraction strip loading device for loading the extraction strip, a sample holder loading device for loading and unloading samples, an extraction strip transfer gripper for driving the extraction strip to move to a preset position, a nucleic acid extraction device for purifying the samples to obtain nucleic acids, a PCR detection device for performing fluorescent PCR detection on the nucleic acids, and a control device, wherein the extraction strip loading device, the sample holder loading device, the extraction strip transfer gripper, the nucleic acid extraction device and the PCR detection device are all connected to the control device. The problems of relatively poor flexibility and relatively low detection efficiency of a nucleic acid extraction and detection system can be ameliorated, so that a sample detection process is more flexible and convenient.

公开(公告)号：US20250067762A1

公开(公告)日：2025-02-27

申请号：US18725146

申请日：2022-12-23

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Peng ZHAO ,  Can XU ,  Xingsen ZANG ,  Kewei CHEN ,  Zongpin JIIANG ,  Baojun WU ,  Zhiguang ZHU ,  Jiangping HOU ,  Chao WANG ,  Cong LIU

IPC: G01N35/04 ,  B67B7/15 ,  G01N35/00

Abstract: An online uncapping system includes a sample intake rail, a scanning blocking mechanism, a sample container information scanning apparatus, an uncapping blocking mechanism, a sample tube clamping mechanism, a sample tube uncapping device, and a cap receiving mechanism. The scanning blocking mechanism is arranged on one side of the sample intake rail; the sample container information scanning apparatus is configured to read information about the sample tube blocked by the scanning blocking mechanism; the uncapping blocking mechanism is arranged on one side of the sample inlet rail and configured to block and release the sample tube; the sample tube clamping mechanism is configured to clamp the sample tube blocked by the uncapping blocking mechanism; the sample tube uncapping device is configured to uncover the sample tube blocked by the uncapping blocking mechanism; and the cap receiving mechanism is configured to collect the tube cap.

公开(公告)号：US20250062019A1

公开(公告)日：2025-02-20

申请号：US18725128

申请日：2022-12-23

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Can XU ,  Peng ZHAO ,  Yanjie CUI ,  Shuai ZHANG ,  Qingdong CUI ,  Baojun WU ,  Zhiguang ZHU ,  Jianping HOU ,  Chao WANG ,  Cong LIU

IPC: G16H40/67 ,  B04B7/00 ,  B04B13/00

Abstract: An online centrifugal system includes a conveying device, a balancing and weighing mechanism, a manipulator, and a centrifuge. The conveying device, the balancing and weighing mechanism and the centrifuge are sequentially arranged. The conveying device is used to convey a sample holder for holding blood collection tubes, the balancing and weighing mechanism is used to weigh an adapter, and the centrifuge is used to perform centrifugation to blood collection tubes. The manipulator is used to grab the blood collection tubes and the adapter respectively, to convey the blood collection tubes between the adapter and the conveying device, and convey the adapter between the centrifuge and the balancing and weighing mechanism. An inlet and outlet window is provided on the centrifuge for passage of the adapter. The balancing and weighing mechanism is used to balance the adapter, thereby meeting balancing needs of the adapter.

公开(公告)号：US20240069052A1

公开(公告)日：2024-02-29

申请号：US18269951

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Chao WANG ,  Peng ZHAO ,  Pengtao WU ,  Yang PAN ,  Yaoji LIU ,  Zhenkun LI ,  Cong LIU

IPC: G01N35/10 ,  B08B3/04 ,  B08B13/00 ,  G01N35/00

CPC classification number: G01N35/1004 ,  B08B3/04 ,  B08B13/00 ,  G01N35/00732

Abstract: A cartridge preprocessing system applied to an automated molecular diagnostics instrument is provided. The cartridge preprocessing system includes a piercing device and a cleaning device. The piercing device includes a drive assembly and a piercing member, and the drive assembly is configured to control the piercing member to alternately move to a piercing station and a cleaning station. The piercing member is configured to pierce a barrier film of a cartridge that moves to the piercing station, and the cleaning device is configured to clean the piercing member that moves to the cleaning station.

公开(公告)号：US20240371620A1

公开(公告)日：2024-11-07

申请号：US18552695

申请日：2022-11-15

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Keya CAI ,  Xiangguang LI ,  Yuanhe SHANG ,  Lele HAN ,  Shichuang CHEN ,  Yunzhao WU ,  Ruifeng ZHANG ,  Cong LIU

IPC: H01J49/02 ,  H01J49/00 ,  H01J49/06 ,  H01J49/22

Abstract: A method and a system for selecting ions in a mass spectrometer. The method comprises: applying a first voltage to a deflection conductor to generate a deflection electric field at the deflection conductor, where ions are deflected to a trajectory not reaching the detector when flying through the deflection electric field; maintaining the first voltage applied to the deflection conductor to deflect non-target ions which fly out of the acceleration electric field, in response to detecting that a pulse synchronized with a laser is outputted; applying a second voltage to the deflection conductor to stop generating the deflection electric field and enable target ions to reach the detector, in response to the target ions flying out of the acceleration electric field; and applying the first voltage to the deflection conductor, in response to all target ions flying past the deflection conductor.

公开(公告)号：US20240238790A1

公开(公告)日：2024-07-18

申请号：US18560381

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Long SUN ,  Chao WANG ,  Peng ZHAO ,  Zhenkun LI ,  Chaohui ZHANG ,  Cong LIU

IPC: B01L9/00 ,  B01L9/02 ,  B01L9/06

CPC classification number: B01L9/523 ,  B01L9/02 ,  B01L9/06 ,  B01L9/56

Abstract: A basket includes a cover plate, a support assembly, a basket bottom plate for holding at least two rows of reagent strips, and a sample holder for holding at least two sample tubes; the sample holder is detachably connected to an end surface of the basket bottom plate; the cover plate and the basket bottom plate are rotatably connected so as to limit displacement of the reagent strips in the height direction when the cover plate and the basket bottom plate are attached to each other; the support assembly is connected to the bottom surface of the basket bottom plate, and the height of the support assembly is greater than or equal to the heights of the reagent strips.

公开(公告)号：US20240093176A1

公开(公告)日：2024-03-21

申请号：US18038230

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Peng ZHAO ,  Yang PAN ,  Yaoji LIU ,  Chao WANG ,  Cong LIU

IPC: C12N15/10

CPC classification number: C12N15/1003

Abstract: An automatic loading system for an extraction strip includes: an extraction strip for holding several reagents, a first channel, a second channel parallel to and attached to the first channel, a first hand pushing device for pushing the extraction strip to move in the first channel, a second hand pushing device for pushing the extraction strip to move in the second channel, and a transfer device for transferring the extraction strip from the first channel to the second channel. One end of the first channel is a loading inlet of the extraction strip. One end of the second channel is a grabbing position of the extraction strip. The transfer device is arranged at the other ends of the first channel and the second channel. The first hand pushing device and the second hand pushing device can move transversely and move up and down.