-
公开(公告)号：US12012591B2
公开(公告)日：2024-06-18
申请号：US17316054
申请日：2021-05-10
Applicant: Joseph Francis Liberti , BIOMAGNETIC SOLUTIONS LLC.
Inventor： Paul A. Liberti , Todor R. Khristov , Dustin W. Ritter
IPC: C12N13/00 , A61M1/36 , B01D15/38 , B01F31/23 , B01F33/452 , B03C1/01 , B03C1/033 , B03C1/034 , B03C1/28 , G01N33/543
CPC classification number: C12N13/00 , A61M1/3618 , B01D15/3885 , B01F31/23 , B01F33/452 , B03C1/01 , B03C1/0332 , B03C1/034 , B03C1/288 , G01N33/54326 , B03C2201/18 , B03C2201/22 , B03C2201/26
Abstract: An apparatus and methods are provided for the magnetic separation of target bioentities. The apparatus includes a fluid chamber and a magnetic element for drawing target bioentities toward a collection surface of the fluid chamber. The apparatus may include a positioning assembly operable to variable change the position and orientation f the fluid chamber relative to the magnetic element.
-
公开(公告)号：US20220387677A1
公开(公告)日：2022-12-08
申请号：US17887651
申请日：2022-08-15
Applicant: BIOMAGNETIC SOLUTIONS LLC
Inventor： Paul A. Liberti , Dustin W. Ritter
Abstract: Method consists of placing a flexible container within a rigid frame and expanding the container by pneumatic or hydraulic pressure such that the walls of the container conform to the inside walls of the rigid frame thus forming a well-defined chamber. The system has the capability of reducing the volume of the chamber by adjusting the distance between the walls of the rigid container. The methods and systems so described are applicable to closed sterile systems that employ immunomagnetic isolation or purging of components from blood products. By providing a fixed volume and at least one surface upon which targeted entities can be magnetically deposited, target cells in the case of positive isolations can be magnetically held, flushed with wash buffers over them to remove entrapped cells and finally the recovery of product of extremely high purities and at high yields.
-
Search Results
2
records
(took 0.013 seconds)
