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公开(公告)号：US10968453B2
公开(公告)日：2021-04-06
申请号：US16849583
申请日：2020-04-15
Applicant: Biogen MA Inc.
Inventor： Eric E. Swayze
IPC: C12N15/113
Abstract: Disclosed herein are antisense compounds and methods for decreasing SOD-1 mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate SOD-1 associated diseases, disorders, and conditions. Such SOD-1 associated diseases include amyotrophic sclerosis (ALS).
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公开(公告)号：US10385341B2
公开(公告)日：2019-08-20
申请号：US15301004
申请日：2015-04-01
Applicant: Biogen MA Inc.
Inventor： Eric E. Swayze
IPC: C07H21/04 , C12N15/113
Abstract: Disclosed herein are antisense compounds and methods for decreasing SOD-1 mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate SOD-1 associated diseases, disorders, and conditions. Such SOD-1 associated diseases include amyotrophic sclerosis (ALS).
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公开(公告)号：US11591595B2
公开(公告)日：2023-02-28
申请号：US16986770
申请日：2020-08-06
Applicant: Biogen MA Inc.
Inventor： Holly Kordasiewicz , Eric E. Swayze , Susan M. Freier , Huynh-Hoa Bui
IPC: C12N15/113 , A61K31/711 , C07H21/02
Abstract: Disclosed herein are antisense compounds and methods for decreasing Tau mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate Tau-associated diseases, disorders, and conditions.
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公开(公告)号：US20230323351A1
公开(公告)日：2023-10-12
申请号：US18155945
申请日：2023-01-18
Applicant: Biogen MA Inc.
Inventor： Holly Kordasiewicz , Eric E. Swayze , Susan M. Freier , Huynh-Hoa Bui
IPC: C12N15/113 , A61K31/711 , C07H21/02
CPC classification number: C12N15/113 , A61K31/711 , C07H21/02 , C12N2310/11 , C12N2310/315 , C12N2310/3341 , C12N2310/341 , C12N2310/345 , C12N2310/346
Abstract: Disclosed herein are antisense compounds and methods for decreasing Tau mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate Tau-associated diseases, disorders, and conditions.
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Patent Agency Ranking
公开(公告)号：US20210071176A1
公开(公告)日：2021-03-11
申请号：US16986770
申请日：2020-08-06
Applicant: Biogen MA Inc.
Inventor： Holly Kordasiewicz , Eric E. Swayze , Susan M. Freier , Huynh-Hoa Bui
IPC: C12N15/113 , A61K31/711 , C07H21/02
Abstract: Disclosed herein are antisense compounds and methods for decreasing Tau mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate Tau-associated diseases, disorders, and conditions.
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公开(公告)号：US10793856B2
公开(公告)日：2020-10-06
申请号：US15593173
申请日：2017-05-11
Applicant: Biogen MA Inc.
Inventor： Holly Kordasiewicz , Eric E. Swayze , Susan M. Freier , Huynh-Hoa Bui
IPC: C12N15/113 , A61K31/711 , C07H21/02 , C12Q1/68
Abstract: Disclosed herein are antisense compounds and methods for decreasing Tau mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate Tau-associated diseases, disorders, and conditions.
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公开(公告)号：US10669546B2
公开(公告)日：2020-06-02
申请号：US16513297
申请日：2019-07-16
Applicant: Biogen MA Inc.
Inventor： Eric E. Swayze
IPC: C07H21/04 , C12N15/113
Abstract: Disclosed herein are antisense compounds and methods for decreasing SOD-1 mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate SOD-1 associated diseases, disorders, and conditions. Such SOD-1 associated diseases include amyotrophic sclerosis (ALS).
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公开(公告)号：US12091662B2
公开(公告)日：2024-09-17
申请号：US18155945
申请日：2023-01-18
Applicant: Biogen MA Inc.
Inventor： Holly Kordasiewicz , Eric E. Swayze , Susan M. Freier , Huynh-Hoa Bui
IPC: C12N15/113 , A61K31/711 , C07H21/02 , C12Q1/68
CPC classification number: C12N15/113 , A61K31/711 , C07H21/02 , C12N2310/11 , C12N2310/315 , C12N2310/3341 , C12N2310/341 , C12N2310/345 , C12N2310/346 , C12N2310/321 , C12N2310/3525
Abstract: Disclosed herein are antisense compounds and methods for decreasing Tau mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate Tau-associated diseases, disorders, and conditions.
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公开(公告)号：US20200040342A1
公开(公告)日：2020-02-06
申请号：US16513297
申请日：2019-07-16
Applicant: Biogen MA Inc.
Inventor： Eric E. Swayze
IPC: C12N15/113
Abstract: Disclosed herein are antisense compounds and methods for decreasing SOD-1 mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate SOD-1 associated diseases, disorders, and conditions. Such SOD-1 associated diseases include amyotrophic sclerosis (ALS).
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