公开(公告)号：US10274715B2

公开(公告)日：2019-04-30

申请号：US14812874

申请日：2015-07-29

Applicant: CELLOMICS, INC.

Inventor： Ronald Albert Kuhn ,  Kim Anthony Ippolito ,  Dirk John Vandenberg, III

IPC: G02B7/36 ,  G02B7/28 ,  G02B21/00 ,  G02B21/16 ,  G02B21/24 ,  G02B21/36 ,  H04N5/232

Abstract: Accurate, reliable, and robust laser-based autofocus solutions are presented for through-the-lens microscope applications using slides or micro-titer plates. The laser-based autofocus solutions solve many of the problems that have arisen due to multiple reflective surfaces at varying distances relative to a sample of interest. The laser-based autofocus solutions provide a unique solution to resolve the ambiguity caused by these multiple reflective surfaces by using an image-based approach.

公开(公告)号：US20160041380A1

公开(公告)日：2016-02-11

申请号：US14812874

申请日：2015-07-29

Applicant: CELLOMICS, INC.

Inventor： Ronald Albert Kuhn ,  Kim Anthony Ippolito ,  Dirk John Vandenberg, III

IPC: G02B21/36 ,  H04N5/232 ,  G02B7/36

CPC classification number: G02B21/365 ,  G02B7/28 ,  G02B7/36 ,  G02B21/0088 ,  G02B21/16 ,  G02B21/244 ,  G02B21/245 ,  G02B21/361 ,  G02B21/367 ,  H04N5/23212

Abstract: Accurate, reliable, and robust laser-based autofocus solutions are presented for through-the-lens microscope applications using slides or micro-titer plates. The laser-based autofocus solutions solve many of the problems that have arisen due to multiple reflective surfaces at varying distances relative to a sample of interest. The laser-based autofocus solutions provide a unique solution to resolve the ambiguity caused by these multiple reflective surfaces by using an image-based approach.

Abstract translation: 为使用幻灯片或微滴定板的透镜显微镜应用提出了准确，可靠和强大的基于激光的自动对焦解决方案。 基于激光的自动对焦解决方案解决了由于多个反射表面相对于感兴趣的样品而在不同距离处产生的许多问题。 基于激光的自动对焦解决方案提供了一种独特的解决方案，可以通过使用基于图像的方法来解决由这些多个反射面引起的模糊性。