公开(公告)号：US20140022507A1

公开(公告)日：2014-01-23

申请号：US14033986

申请日：2013-09-23

Applicant: CIBA Vision Corporation

Inventor： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorge Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

IPC: G02C7/04

CPC classification number: G02C7/049 ,  A61L27/26 ,  A61L27/34 ,  A61L2430/16 ,  B05D1/62 ,  B29C39/42 ,  B29C71/00 ,  B29D11/00076 ,  B29L2011/0041 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  G02B1/043 ,  Y10S525/903 ,  Y10S525/936 ,  Y10S525/937 ,  C08L51/085 ,  C08L51/08 ,  C08L33/00 ,  C08L83/04 ,  C08L39/06 ,  C08G18/63 ,  C08G18/48

Abstract: A method for making a silicone hydrogel contact lens is provided. In one embodiment, a prepolymer mixture is polymerized in a lens mold in an atmosphere having less than about 10000 ppm oxygen to form a silicone hydrogel contact lens suitable for extended wear as characterized by producing less than 10% corneal swelling after a period of continuous wear of 7 days including normal sleep periods. In one embodiment, the prepolymer mixture comprises at least one oxyperm material containing hydrophilic groups, wherein the at least one oxyperm material is a siloxane-containing macromer or monomer, at least one ionperm material, and a cross-linking agent. In certain embodiments, the polymerization of the prepolymer mixture may be carried out in an atmosphere having less than about 1000 ppm oxygen.

Abstract translation: 提供了制备硅酮水凝胶隐形眼镜的方法。 在一个实施方案中，预聚物混合物在具有小于约10000ppm氧气的气氛中在透镜模具中聚合以形成适于延长磨损的硅氧烷水凝胶隐形眼镜，其特征在于连续磨损一段时间后产生小于10％的角膜溶胀 包括正常睡眠期为7天。 在一个实施方案中，预聚物混合物包含至少一种含有亲水基团的含氧物质，其中所述至少一种含氧物质是含硅氧烷的大分子单体或单体，至少一种离子精子材料和交联剂。 在某些实施方案中，预聚物混合物的聚合可以在具有小于约1000ppm氧气的气氛中进行。

公开(公告)号：US09612455B2

公开(公告)日：2017-04-04

申请号：US14033986

申请日：2013-09-23

Applicant: CIBA Vision Corporation

Inventor： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorge Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

IPC: G02C7/04 ,  A61L27/26 ,  A61L27/34 ,  B29C39/42 ,  C08G18/10 ,  C08G18/48 ,  C08G18/50 ,  C08G18/61 ,  C08G18/67 ,  C08G18/81 ,  G02B1/04 ,  B05D1/00 ,  B29D11/00 ,  B29C71/00 ,  B29L11/00

CPC classification number: G02C7/049 ,  A61L27/26 ,  A61L27/34 ,  A61L2430/16 ,  B05D1/62 ,  B29C39/42 ,  B29C71/00 ,  B29D11/00076 ,  B29L2011/0041 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  G02B1/043 ,  Y10S525/903 ,  Y10S525/936 ,  Y10S525/937 ,  C08L51/085 ,  C08L51/08 ,  C08L33/00 ,  C08L83/04 ,  C08L39/06 ,  C08G18/63 ,  C08G18/48

Abstract: A method for making a silicone hydrogel contact lens is provided. In one embodiment, a prepolymer mixture is polymerized in a lens mold in an atmosphere having less than about 10000 ppm oxygen to form a silicone hydrogel contact lens suitable for extended wear as characterized by producing less than 10% corneal swelling after a period of continuous wear of 7 days including normal sleep periods. In one embodiment, the prepolymer mixture comprises at least one oxyperm material containing hydrophilic groups, wherein the at least one oxyperm material is a siloxane-containing macromer or monomer, at least one ionperm material, and a cross-linking agent. In certain embodiments, the polymerization of the prepolymer mixture may be carried out in an atmosphere having less than about 1000 ppm oxygen.