公开(公告)号：US20130169954A1

公开(公告)日：2013-07-04

申请号：US13751181

申请日：2013-01-28

Applicant: CIENCIA, INC.

Inventor： George N. Gibson ,  Ernest F. Guignon ,  Michael T. Reilly

IPC: G01N21/55

CPC classification number: G01N21/55 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/10 ,  G01J3/4406 ,  G01N21/553 ,  G01N21/648 ,  G01N21/7743

Abstract: An instrument for measuring and analyzing surface plasmon resonance on a sensor surface has a polarized light source optically connected to the sensor surface by a plurality of optical elements, including in one embodiment an optical telescope that transfers light from a rotatable reflecting surface to the sensor surface. Selective positioning of a cylindrical lens into a first position within the path of light transforms collimated light to a rectangular wedge that is incident upon the sensor surface at numerous angles. In another embodiment, the light source is operated as a laser to excite fluorescence on the sensor surface and the fluorescence is selectively directed to a detector by appropriate optical elements positioned in specific configurations.

Abstract translation: 用于测量和分析传感器表面上的表面等离子体共振的仪器具有通过多个光学元件光学连接到传感器表面的偏振光源，在一个实施例中包括将光从可旋转反射表面传输到传感器表面的光学望远镜 。 将柱面透镜选择性地定位在光路内的第一位置将准直光转换成以多个角度入射在传感器表面上的矩形楔形物。 在另一个实施例中，光源作为激光器操作以在传感器表面上激发荧光，并且通过以特定配置定位的适当的光学元件将荧光选择性地导向检测器。

公开(公告)号：US08526001B2

公开(公告)日：2013-09-03

申请号：US13751181

申请日：2013-01-28

Applicant: Ciencia, Inc.

Inventor： George N. Gibson ,  Ernest F. Guignon ,  Michael T. Reilly

IPC: G01N21/55

CPC classification number: G01N21/55 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/10 ,  G01J3/4406 ,  G01N21/553 ,  G01N21/648 ,  G01N21/7743

Abstract: An instrument for measuring and analyzing surface plasmon resonance on a sensor surface has a polarized light source optically connected to the sensor surface by a plurality of optical elements, including in one embodiment an optical telescope that transfers light from a rotatable reflecting surface to the sensor surface. Selective positioning of a cylindrical lens into a first position within the path of light transforms collimated light to a rectangular wedge that is incident upon the sensor surface at numerous angles. In another embodiment, the light source is operated as a laser to excite fluorescence on the sensor surface and the fluorescence is selectively directed to a detector by appropriate optical elements positioned in specific configurations.