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公开(公告)号：US10696688B2
公开(公告)日：2020-06-30
申请号：US15774520
申请日：2016-11-21
Inventor： Sandip Bibishan Bharate , Shashi Bhushan , Shabber Mohammed , Santosh Kumar Guru , Sonali Sandip Bharate , Vikas Kumar , Girish Mahajan , Mubashir Javed Mintoo , Dilip Manikrao Mondhe , Ram Vishwakarma
IPC: C07D493/04 , C07D495/04 , C07D471/14
Abstract: The present invention relates to fused pyrimidines of formulae I and II wherein, R1, R2 are as herein described. The present invention particularly relates to isoform selective PI3Kα inhibition and their medicinal use as anticancer agents.
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Patent Agency Ranking
公开(公告)号：US12036214B2
公开(公告)日：2024-07-16
申请号：US17253193
申请日：2019-06-14
Inventor： Sonali Sandip Bharate , Vikas Kumar , Mubashir Javed Mintoo , Dilip Manikrao Mondhe , Sandip Bibishan Bharate , Ram Vishwakarma
IPC: A61K31/453 , A61K9/10 , A61K9/20 , A61K47/10 , A61K47/32 , A61K47/38 , A61K47/40 , A61P35/00 , C07D405/04
CPC classification number: A61K31/453 , A61K9/10 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K47/10 , A61K47/32 , A61K47/38 , A61K47/40 , A61P35/00
Abstract: The present invention is related to the novel solid dispersion formulations of an anticancer compound of formula A and a process for preparing the same wherein the anticancer compound is formulated with hydrophilic polymer. The said formulation showed enhanced dissolution of the anticancer compound and improved in-vivo anticancer activity. The said formulations are useful for the treatment of various types of cancer.
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公开(公告)号：US11878075B2
公开(公告)日：2024-01-23
申请号：US17046007
申请日：2019-04-18
Inventor： Sonali Sandip Bharate , Vikas Kumar , Mehak Gupta , Sumit Gandhi , Ajay Kumar , Sandip Bibishan Bharate , Ram Vishwakarma
CPC classification number: A61K9/1635 , A61K9/1652 , A61K36/58
Abstract: The present invention relates to the novel formulation for sustained or delayed release of rohitukine-rich Dysoxylum binectariferum extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract/fraction of rohitukine-rich Dysoxylum binectariferum with polymers has resulted in a sustained release of the extract or fraction over a period of 16-24 hrs. The said formulations are useful in the treatment of inflammatory diseases.
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公开(公告)号：US12201727B2
公开(公告)日：2025-01-21
申请号：US18380054
申请日：2023-10-13
Inventor： Sonali Sandip Bharate , Vikas Kumar , Mehak Gupta , Sumit Gandhi , Ajay Kumar , Sandip Bibishan Bharate , Ram Vishwakarma
Abstract: The present invention relates to the novel formulation for sustained or delayed release of rohitukine-rich Dysoxylum binectariferum extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract/fraction of rohitukine-rich Dysoxylum binectariferum with polymers has resulted in a sustained release of the extract or fraction over a period of 16-24 hrs. The said formulations are useful in the treatment of inflammatory diseases.
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公开(公告)号：US12191522B2
公开(公告)日：2025-01-07
申请号：US16490851
申请日：2018-03-05
Inventor： Vikas Kumar , Swaminathan Sivaram , Ver Avadhani Chilukuri
IPC: H01M50/446 , C08G73/18 , C08K3/26 , C08K3/36 , C08L33/24 , H01M10/0525 , H01M50/40 , H01M50/414 , H01M50/489 , H01M50/497
Abstract: The present invention discloses a film comprising porous, amorphous polybenzimidazole (PBI) and at least one filler for use as a separator in a lithium ion battery and a process for preparation thereof.
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公开(公告)号：US20240041772A1
公开(公告)日：2024-02-08
申请号：US18380054
申请日：2023-10-13
Inventor： Sonali Sandip Bharate , Vikas Kumar , Mehak Gupta , Sumit Ghandhi , Ajay Kumar , Sandip Bibishan Bharate , Ram Vishwakarma
CPC classification number: A61K9/1635 , A61K9/1652 , A61K36/58
Abstract: The present invention relates to the novel formulation for sustained or delayed release of rohitukine-rich Dysoxylum binectariferum extract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract/fraction of rohitukine-rich Dysoxylum binectariferum with polymers has resulted in a sustained release of the extract or fraction over a period of 16-24 hrs. The said formulations are useful in the treatment of inflammatory diseases.
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