公开(公告)号：US20230364021A1

公开(公告)日：2023-11-16

申请号：US18354293

申请日：2023-07-18

Applicant: CRITITECH, INC.

Inventor： Jacob SITTENAUER ,  Joseph FARTHING ,  Mark WILLIAMS ,  Michael BALTEZOR ,  Gere DIZEREGA ,  Aranza Barreda ABARCA ,  Shelby CLARK

IPC: A61K9/16 ,  A61K31/44 ,  A61K9/10 ,  A61K47/26 ,  A61K47/38 ,  A61K47/32

CPC classification number: A61K9/1688 ,  A61K31/44 ,  A61K9/10 ,  A61K47/26 ,  A61K47/38 ,  A61K47/32

Abstract: Particles of at least 95% by weight of sorafenib, or a pharmaceutically acceptable salt thereof are provided, wherein the particles have a specific surface area (SSA) of at least 2 m2/g and have a mean particle size by volume distribution of between about 0.7 μm and about 8 μm, as are methods for their use, and methods for making such particles.

公开(公告)号：US20230142186A1

公开(公告)日：2023-05-11

申请号：US18053557

申请日：2022-11-08

Applicant: CRITITECH, INC.

Inventor： Jacob SITTENAUER ,  Aranza Barreda ABARCA ,  Shelby CLARK ,  Joseph FARTHING ,  Mark WILLIAMS ,  Gere DIZEREGA ,  Michael BALTEZOR

IPC: A61K31/55 ,  A61K9/16

CPC classification number: A61K31/55 ,  A61K9/1688 ,  A61K9/16

Abstract: Compositions of particles having at least 95% by weight of rucaparib and a specific surface area (SSA) of at least 12 m2/g, methods for their use, and methods for their production are provided.

公开(公告)号：US20200247780A1

公开(公告)日：2020-08-06

申请号：US16650670

申请日：2018-09-28

Applicant: CRITITECH, INC.

Inventor： Mark WILLIAMS ,  Jacob SITTENAUER ,  Shelby CLARK ,  Joseph FARTHING ,  Michael BALTEZOR ,  Matthew MCCLOREY

IPC: C07D401/10 ,  A61K9/14 ,  A61K9/00 ,  A61P31/04

Abstract: The present disclosure relates to ciprofloxacin polymorphs and their use in treating infections.

公开(公告)号：US20160374953A1

公开(公告)日：2016-12-29

申请号：US15261108

申请日：2016-09-09

Applicant: CRITITECH, INC.

Inventor： Michael BALTEZOR ,  Joseph FARTHING ,  Jake SITTENAUER ,  Jahna ESPINOSA ,  Samuel CAMPBELL ,  Matthew MCCLOREY ,  Julia K. FISCHER ,  Mark D. WILLIAMS

IPC: A61K9/51 ,  A61K31/337

CPC classification number: A61K31/337 ,  A61J3/02 ,  A61K9/0019 ,  A61K9/10 ,  A61K9/14 ,  A61K9/1605 ,  A61K9/1682 ,  A61K9/1688 ,  A61K9/5192 ,  B01D46/24 ,  B01D2271/02 ,  B01J2/04 ,  B01J3/008 ,  B01J3/02 ,  B01J4/002 ,  B01J19/10 ,  B01J19/26 ,  B05B1/3489 ,  B05B13/0278 ,  B05D2401/90

Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.

Abstract translation: 提供的组合物包括具有至少95重量％的紫杉烷或其药学上可接受的盐，其中颗粒的平均堆积密度为约0.050g / cm 3至约0.15g / cm 3，和/或比表面积 面积（SSA）至少为18m2 / g，20m2 / g，25m2 / g，30m2 / g，32m2 / g，34m2 / g或35m2 / g。 还提供了制备和使用这些组合物的方法。

公开(公告)号：US20220241257A1

公开(公告)日：2022-08-04

申请号：US17381705

申请日：2021-07-21

Applicant: CRITITECH, INC.

Inventor： Jacob SITTENAUER ,  Joseph FARTHING ,  Mark WILLIAMS ,  Michael BALTEZOR ,  Gere DIZEREGA ,  Aranza Barreda ABARCA ,  Shelby CLARK

IPC: A61K31/44 ,  A61K9/16

Abstract: The disclosure provides particles of at least 95% by weight of sorafenib, or a pharmaceutically acceptable salt thereof, wherein the particles have a specific surface area (SSA) of at least 2 m2/g and have a mean particle size by volume distribution of between about 0.7 μm and about 8 μm, methods for their use, and methods for making such particles.

公开(公告)号：US20210387961A1

公开(公告)日：2021-12-16

申请号：US17401654

申请日：2021-08-13

Applicant: CRITITECH, INC.

Inventor： Mark WILLIAMS ,  Jacob SITTENAUER ,  Shelby CLARK ,  Joseph FARTHING ,  Michael BALTEZOR ,  Matthew MCCLOREY

IPC: C07D401/10 ,  A61P31/04 ,  A61K9/14 ,  A61K9/00

Abstract: The present disclosure relates to ciprofloxacin polymorphs and their use in treating infections.

公开(公告)号：US20200163928A1

公开(公告)日：2020-05-28

申请号：US16776919

申请日：2020-01-30

Applicant: CRITITECH, INC.

Inventor： Michael BALTEZOR ,  Joseph FARTHING ,  Jake SITTENAUER ,  Jahna ESPINOSA ,  Samuel CAMPBELL ,  Matthew MCCLOREY ,  Julia K. FISCHER ,  Mark D. WILLIAMS ,  Gary E. CLAPP

IPC: A61K31/337 ,  A61K9/51 ,  A61K9/16 ,  B05B13/02 ,  A61K9/10 ,  A61K9/00 ,  A61J3/02 ,  B01J3/00 ,  B05B1/34 ,  B01D46/24 ,  B01J4/00 ,  B01J19/10 ,  B01J2/04 ,  A61K9/14 ,  B01J19/26 ,  B01J3/02

Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.

公开(公告)号：US20170224650A1

公开(公告)日：2017-08-10

申请号：US15499397

申请日：2017-04-27

Applicant: CRITITECH, INC.

Inventor： Michael BALTEZOR ,  Joseph FARTHING ,  Jake SITTENAUER ,  Jahna ESPINOSA ,  Samuel CAMPBELL ,  Matthew MCCLOREY ,  Julia K. FISCHER ,  Mark D. WILLIAMS

IPC: A61K31/337 ,  B01J3/00 ,  B01J3/02 ,  A61K9/16

CPC classification number: A61K31/337 ,  A61J3/02 ,  A61K9/0019 ,  A61K9/10 ,  A61K9/14 ,  A61K9/1605 ,  A61K9/1682 ,  A61K9/1688 ,  A61K9/5192 ,  B01D46/24 ,  B01D2271/02 ,  B01J2/04 ,  B01J3/008 ,  B01J3/02 ,  B01J4/002 ,  B01J19/10 ,  B01J19/26 ,  B05B1/3489 ,  B05B13/0278 ,  B05D2401/90

Abstract: Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm3 and about 0.15 g/cm3, and/or a specific surface area (SSA) of at least 18 m2/g, 20 m2/g, 25 m2/g, 30 m2/g, 32 m2/g, 34 m2/g, or 35 m2/g. Methods for making and using such compositions are also provided.

公开(公告)号：US20240216424A1

公开(公告)日：2024-07-04

申请号：US18556705

申请日：2022-04-25

Applicant: CRITITECH, INC.

Inventor： Jacob SITTENAUER ,  Aranza Barreda ABARCA ,  Joseph FARTHING ,  Mark WILLIAMS ,  Michael BALTEZOR

IPC: A61K33/243 ,  A61K9/12 ,  A61K9/16 ,  A61P31/00

CPC classification number: A61K33/243 ,  A61K9/12 ,  A61K9/1629 ,  A61P31/00

Abstract: Compositions of particles having at least 95% by weight of cisplatin and a specific surface area (8SA) of at least 3.5 m2/g. methods for their use. and methods for their production are provided.

公开(公告)号：US20230142591A1

公开(公告)日：2023-05-11

申请号：US18053491

申请日：2022-11-08

Applicant: CRITITECH, INC.

Inventor： Jacob SITTENAUER ,  Aranza Barreda ABARCA ,  Shelby CLARK ,  Joseph FARTHING ,  Mark WILLIAMS ,  Gere DIZEREGA ,  Michael BALTEZOR

IPC: A61K31/454 ,  A61K9/00 ,  A61K9/16

CPC classification number: A61K31/454 ,  A61K9/008 ,  A61K9/1688

Abstract: Compositions of particles having at least 95% by weight of niraparib and a specific surface area (SSA) of at least 5 m2/g, methods for their use, and methods for their production are provided.