公开(公告)号：US20240271194A1

公开(公告)日：2024-08-15

申请号：US18568005

申请日：2022-06-08

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Long CAI ,  Chee Huat (Linus) ENG ,  Yujing YANG

IPC: C12Q1/6841 ,  G16B30/10

CPC classification number: C12Q1/6841 ,  G16B30/10 ,  C12Q2600/166

Abstract: Disclosed herein are methods for generating an ratiometric symbol for sequential hybridization barcoding for multiplexed Fluorescence In Situ Hybridization (FISH). Also, the disclosure sets forth methods, in addition to using the same, and other solutions to problems in the relevant field.

公开(公告)号：US20210395804A1

公开(公告)日：2021-12-23

申请号：US17352162

申请日：2021-06-18

Applicant: California Institute of Technology

Inventor： Long CAI ,  Chee Huat (Linus) ENG ,  James J. PARK ,  Yujing YANG ,  Michal POLONSKY

IPC: C12Q1/6837 ,  C12Q1/6841 ,  G01N33/68 ,  G01N33/543

Abstract: This disclosure herein sets forth embodiments to provide a serological test to detect target analytes that can scale to up to 10,000 or more samples in a single run. This disclosure herein sets forth methods to allow for unique barcoding by using a multi-level barcode scheme that is modular and enables easy detection of multiple analytes in samples.