公开(公告)号：US20220362380A1

公开(公告)日：2022-11-17

申请号：US17294521

申请日：2020-11-10

Applicant: Cochlear Limited

Inventor： Jonathon Kirk ,  Daniel Smyth ,  Ya Lang Enke ,  Wolfram Frederik Dueck

IPC: A61K41/00 ,  A61K9/127 ,  A61K9/00 ,  A61N1/05

Abstract: Presented herein are techniques for localized release of systemically circulating therapeutic substances, which combine many of the advantages of systematic and localized administration, while eliminating many of the associated drawbacks. More specifically, in accordance with the techniques presented herein, an electro-responsive biomaterial is systemically administered to a recipient of an electrically-stimulating implantable medical device. The electro-responsive biomaterial comprises a therapeutic substance that is only activated (e.g., released) in the presence of an electromagnetic field generated by the electrically-stimulating implantable medical device.