公开(公告)号：US20230039098A1

公开(公告)日：2023-02-09

申请号：US17960805

申请日：2022-10-05

Applicant: Cornell University

Inventor： Chris Xu ,  Kriti Charan ,  Bo Li ,  Michael Buttolph

IPC: A61B5/00 ,  H01S3/067 ,  G02B21/00

Abstract: A system and method for adaptive illumination, the imaging system comprising an excitation source having a modulator, which generates a pulse intensity pattern having a first wavelength when the excitation source receives a modulation pattern. The modulation pattern is a data sequence of a structural image of a sample. An amplifier of the imaging system is configured to receive and amplify the pulse intensity pattern from the modulator. A frequency shift mechanism of the imaging system shifts the first wavelength of the pulse intensity pattern to a second wavelength. A laser scanning microscope of the imaging system receives the pulse intensity pattern having the second wavelength.

公开(公告)号：US20200069233A1

公开(公告)日：2020-03-05

申请号：US16344157

申请日：2017-11-15

Applicant: CORNELL UNIVERSITY

Inventor： Chris Xu ,  Kriti Charan ,  Bo Li ,  Michael Buttolph

IPC: A61B5/00 ,  H01S3/067

Abstract: A system and method for adaptive illumination, the imaging system comprising an excitation source having a modulator, which generates a pulse intensity pattern having a first wavelength when the excitation source receives a modulation pattern. The modulation pattern is a data sequence of a structural image of a sample. An amplifier of the imaging system is configured to receive and amplify the pulse intensity pattern from the modulator. A frequency shift mechanism of the imaging system shifts the first wavelength of the pulse intensity pattern to a second wavelength. A laser scanning microscope of the imaging system receives the pulse intensity pattern having the second wavelength.

公开(公告)号：US11944448B2

公开(公告)日：2024-04-02

申请号：US17960805

申请日：2022-10-05

Applicant: Cornell University

Inventor： Chris Xu ,  Kriti Charan ,  Bo Li ,  Michael Buttolph

IPC: A61B5/00 ,  G02B21/00 ,  H01S3/067

CPC classification number: A61B5/40 ,  A61B5/0071 ,  G02B21/0032 ,  H01S3/06754 ,  G01N2201/0697

Abstract: A system and method for adaptive illumination, the imaging system comprising an excitation source having a modulator, which generates a pulse intensity pattern having a first wavelength when the excitation source receives a modulation pattern. The modulation pattern is a data sequence of a structural image of a sample. An amplifier of the imaging system is configured to receive and amplify the pulse intensity pattern from the modulator. A frequency shift mechanism of the imaging system shifts the first wavelength of the pulse intensity pattern to a second wavelength. A laser scanning microscope of the imaging system receives the pulse intensity pattern having the second wavelength.

公开(公告)号：US11607165B2

公开(公告)日：2023-03-21

申请号：US16344157

申请日：2017-11-15

Applicant: CORNELL UNIVERSITY

Inventor： Chris Xu ,  Kriti Charan ,  Bo Li ,  Michael Buttolph

IPC: G01J3/04 ,  A61B5/00 ,  H01S3/067 ,  G02B21/00

Abstract: A system and method for adaptive illumination, the imaging system comprising an excitation source having a modulator, which generates a pulse intensity pattern having a first wavelength when the excitation source receives a modulation pattern. The modulation pattern is a data sequence of a structural image of a sample. An amplifier of the imaging system is configured to receive and amplify the pulse intensity pattern from the modulator. A frequency shift mechanism of the imaging system shifts the first wavelength of the pulse intensity pattern to a second wavelength. A laser scanning microscope of the imaging system receives the pulse intensity pattern having the second wavelength.