公开(公告)号：US11439926B2

公开(公告)日：2022-09-13

申请号：US16701942

申请日：2019-12-03

Applicant: Cytiva BioProcess R&D AB

Inventor： Jan Bergstrom ,  Gunnar Glad ,  Bo-Lennart Johansson ,  Jean-Luc Maloisel ,  Nils Norrman ,  Tobias E. Soderman

IPC: C07K1/20 ,  B01D15/32 ,  B01J20/285 ,  B01J20/287 ,  B01J39/26 ,  B01J20/28 ,  B01J20/32 ,  C07K16/00 ,  C12N7/00 ,  G01N1/40

Abstract: The present invention is within the field of chromatography. More precisely, it relates to a novel chromatography medium, namely a hydrophobic medium provided with different lids excluding molecules over a certain size due to the porosity of the hydrophobic medium and/or the porosity of the lid. The invention also relates to use of the separation medium for purification of large molecules, which do not enter the separation medium, as well as small molecules, which enter the separation medium and are eluted from there.

公开(公告)号：US20220266170A1

公开(公告)日：2022-08-25

申请号：US17741394

申请日：2022-05-10

Applicant: Cytiva BioProcess R&D AB

Inventor： Jan Bergstrom ,  Gunnar Glad ,  Bo-Lennart Johansson ,  Jean-Luc Maloisel ,  Nils Norrman ,  Tobias E. Soderman

IPC: B01D15/32 ,  B01J20/285 ,  B01J20/287 ,  B01J39/26 ,  B01J20/28 ,  B01J20/32 ,  C07K1/20 ,  C07K16/00 ,  C12N7/00 ,  G01N1/40

Abstract: The present invention is within the field of chromatography. More precisely, it relates to a novel chromatography medium, namely a hydrophobic medium provided with different lids excluding molecules over a certain size due to the porosity of the hydrophobic medium and/or the porosity of the lid. The invention also relates to use of the separation medium for purification of large molecules, which do not enter the separation medium, as well as small molecules, which enter the separation medium and are eluted from there.