公开(公告)号：US20240355603A1

公开(公告)日：2024-10-24

申请号：US18693343

申请日：2022-09-21

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Anjali CHELUR ,  Stephen TATE

IPC: H01J49/00

CPC classification number: H01J49/0031 ,  H01J49/0036

Abstract: In one aspect, a method of operating a mass spectrometer is disclosed, which comprises ionizing a sample to generate a plurality of ions, and introducing at least a portion of the ions into an inlet orifice of the mass spectrometer. At least a portion of the ions and/or fragments thereof is detected by a downstream detector to generate a plurality of ion detection events, and the ion detection events are monitored to determine an ion count. The ion count is compared with a reference level to determine whether the detected level exceeds the reference level.