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公开(公告)号：US20240226396A1
公开(公告)日：2024-07-11
申请号：US17909799
申请日：2021-03-17
Applicant: Fenwal, Inc.
Inventor： Benjamin E. Kusters , Richard I. Brown , Kyungyoon Min
CPC classification number: A61M1/0272 , A61M1/3643 , A61M2205/3331 , A61M2205/505
Abstract: A configurable automated blood component manufacturing system includes a durable hardware component and a single use fluid flow circuit. The hardware component includes a pump station, a centrifuge, and a controller including a touchscreen. The hardware component further includes hangers for suspending containers, a weight scale associated with each hanger, a plurality of tubing clamps, and a cassette nesting module including a plurality of valves and pressure sensors. The fluid flow circuit includes a separation chamber received in the centrifuge, a fluid flow control cassette mounted in the cassette nesting module, and a plurality of containers in fluid communication with the fluid flow cassette. The controller is pre-programmed to automatically operate the system to perform one or more standard blood processing procedures selected by an operator by input to the touchscreen, and is configured to be further programmed by the operator to perform additional blood processing procedures.
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公开(公告)号：US20240139398A1
公开(公告)日：2024-05-02
申请号：US18379307
申请日：2023-10-12
Applicant: Fenwal, Inc.
Inventor： Benjamin E. Kusters , Richard I. Brown , Kyungyoon Min
IPC: A61M1/36
CPC classification number: A61M1/3696 , A61M2202/0415 , A61M2202/0429 , A61M2205/3334 , A61M2205/3368
Abstract: A blood processing device includes a pump system, a valve system, a centrifuge, and a controller configured and/or programmed to control the operation of the pump system, the valve system, and the centrifuge to execute a blood separation procedure. The blood separation procedure executed by the controller includes pumping blood into the centrifuge at an inflow rate, separating the blood in the centrifuge into red blood cells and plasma, with an interface between the red blood cells and plasma located at an interface position within the centrifuge, and pumping at least a portion of the red blood cells and at least a portion of the plasma out of the centrifuge. The controller is configured and/or programmed to employ an inflow rate and/or an interface position that is based at least in part on the temperature of the blood.
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3.发明申请公开(公告)号：US20230011431A1
公开(公告)日：2023-01-12
申请号：US17934650
申请日：2022-09-23
Applicant: Fenwal, Inc.
Inventor： Benjamin E. Kusters , Richard I. Brown , Kyungyoon Min
Abstract: A fluid separation device includes a centrifuge in which a fluid is separated into at least two components, with an interface therebetween. At least a portion of one of the separated fluid components is removed from the centrifuge and flows through a vessel. Light is reflected off of the separated fluid component in the vessel and received and analyzed to determine its main wavelength. If the main wavelength is higher than a maximum value, a target location of the interface is changed. If the main wavelength is less than the maximum value, then the location of the interface is compared to the target location. When the interface is sufficiently close to the target location, the optical density of the separated fluid component in the vessel is compared to a minimum value. If the optical density is less than the minimum value, the target location of the interface is changed.
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公开(公告)号：US20220410178A1
公开(公告)日：2022-12-29
申请号：US17899700
申请日：2022-08-31
Applicant: Fenwal, Inc.
Inventor： Kyungyoon Min , Benjamin E. Kusters , Richard I. Brown , Mark J. Brierton
Abstract: A prismatic reflector is provided for incorporation into a centrifugal separation chamber. The prismatic reflector is formed of a light-transmissive material and includes inner and outer walls and first and second end walls. The inner wall is configured to receive light traveling along an initial path and transmit the light to the first end wall, with the first end wall receiving the light transmitted through the inner wall and directing the light toward the second end wall in a direction that is angled with respect to the initial path. The second end wall receives the light from the first end wall and transmits the light out of the prismatic reflector. The initial path of the light may be in a direction toward a rotational axis of the centrifugal separation chamber, with the prismatic reflector redirecting the light into a direction substantially parallel to the rotational axis.
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5.发明申请公开(公告)号：US20200368763A1
公开(公告)日：2020-11-26
申请号：US16878650
申请日：2020-05-20
Applicant: Fenwal, Inc.
Inventor： Benjamin E. Kusters , Richard I. Brown , Kyungyoon Min
Abstract: A fluid separation device includes a centrifuge in which a fluid is separated into at least two components, with an interface therebetween. At least a portion of one of the separated fluid components is removed from the centrifuge and flows through a vessel. Light is reflected off of the separated fluid component in the vessel and received and analyzed to determine its main wavelength. If the main wavelength is higher than a maximum value, a target location of the interface is changed. If the main wavelength is less than the maximum value, then the location of the interface is compared to the target location. When the interface is sufficiently close to the target location, the optical density of the separated fluid component in the vessel is compared to a minimum value. If the optical density is less than the minimum value, the target location of the interface is changed.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20190201916A1
公开(公告)日：2019-07-04
申请号：US16327358
申请日：2017-09-15
Applicant: Fenwal, Inc.
Inventor： Kyungyoon Min , Benjamin E. Kusters , Richard I. Brown , Mark J. Brierton
CPC classification number: B04B5/0442 , A61M1/02 , A61M1/029 , A61M1/265 , A61M1/3693 , A61M2205/3306 , B01D36/045 , B01D63/16 , B04B11/02 , B04B2013/006
Abstract: Systems and methods are provided for separating blood into two or more components. A blood separation system includes a blood separation device and a fluid flow circuit configured to be mounted to the blood separation device. The blood separation device includes a centrifugal separator and a spinning membrane separator drive unit incorporated into a common case, which allows for fluid separation by two different methods. Depending on the separation procedure to be carried out, the fluid flow circuit paired with the blood separation device may include only one separation chamber configured to be mounted to the centrifugal separator or spinning membrane separator drive unit or two separation chambers, with one being mounted to the centrifugal separator and the other to the spinning membrane separator drive unit. The system may be used to separate and collect any combination of red blood cells, plasma, and platelets.
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公开(公告)号：US10058645B2
公开(公告)日：2018-08-28
申请号：US15430730
申请日：2017-02-13
Applicant: Fenwal, Inc.
Inventor： Richard I. Brown
CPC classification number: A61M1/0272 , A61M1/02 , A61M1/3621 , A61M1/3672 , A61M2205/3334 , A61M2205/52 , H05K999/99
Abstract: Systems are provided for anticoagulating blood. Whole blood is drawn from a donor into a system at a draw flow rate. Anticoagulant from an anticoagulant source is pumped into the system at an anticoagulant flow rate to mix with the blood. The anticoagulated blood may be subsequently processed in any of a number of known ways, including separating it and removing at least a portion of one of the components of the blood. Thereafter, at least a portion of the remaining blood may be returned to the donor. The anticoagulant flow rate is independent of the draw flow rate and can be based on a number of factors, including the weight of the donor and the rate at which the donor can metabolize the anticoagulant.
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公开(公告)号：US20170157307A1
公开(公告)日：2017-06-08
申请号：US15430730
申请日：2017-02-13
Applicant: Fenwal, Inc.
Inventor： Richard I. Brown
CPC classification number: A61M1/0272 , A61M1/02 , A61M1/3621 , A61M1/3672 , A61M2205/3334 , A61M2205/52 , H05K999/99
Abstract: Systems are provided for anticoagulating blood. Whole blood is drawn from a donor into a system at a draw flow rate. Anticoagulant from an anticoagulant source is pumped into the system at an anticoagulant flow rate to mix with the blood. The anticoagulated blood may be subsequently processed in any of a number of known ways, including separating it and removing at least a portion of one of the components of the blood. Thereafter, at least a portion of the remaining blood may be returned to the donor. The anticoagulant flow rate is independent of the draw flow rate and can be based on a number of factors, including the weight of the donor and the rate at which the donor can metabolize the anticoagulant.
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公开(公告)号：US12214366B2
公开(公告)日：2025-02-04
申请号：US17899700
申请日：2022-08-31
Applicant: Fenwal, Inc.
Inventor： Kyungyoon Min , Benjamin E. Kusters , Richard I. Brown , Mark J. Brierton
Abstract: A prismatic reflector is provided for incorporation into a centrifugal separation chamber. The prismatic reflector is formed of a light-transmissive material and includes inner and outer walls and first and second end walls. The inner wall is configured to receive light traveling along an initial path and transmit the light to the first end wall, with the first end wall receiving the light transmitted through the inner wall and directing the light toward the second end wall in a direction that is angled with respect to the initial path. The second end wall receives the light from the first end wall and transmits the light out of the prismatic reflector. The initial path of the light may be in a direction toward a rotational axis of the centrifugal separation chamber, with the prismatic reflector redirecting the light into a direction substantially parallel to the rotational axis.
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10.发明授权公开(公告)号：US11850604B2
公开(公告)日：2023-12-26
申请号：US17934650
申请日：2022-09-23
Applicant: Fenwal, Inc.
Inventor： Benjamin E. Kusters , Richard I. Brown , Kyungyoon Min
CPC classification number: B04B11/02 , A61M1/36224 , A61M1/36225 , A61M1/362227 , A61M1/362261 , A61M1/362265 , B04B5/0442 , A61M1/3693 , A61M2202/0415 , A61M2230/30 , B04B2013/006
Abstract: A fluid separation device includes a centrifuge in which a fluid is separated into at least two components, with an interface therebetween. At least a portion of one of the separated fluid components is removed from the centrifuge and flows through a vessel. Light is reflected off of the separated fluid component in the vessel and received and analyzed to determine its main wavelength. If the main wavelength is higher than a maximum value, a target location of the interface is changed. If the main wavelength is less than the maximum value, then the location of the interface is compared to the target location. When the interface is sufficiently close to the target location, the optical density of the separated fluid component in the vessel is compared to a minimum value. If the optical density is less than the minimum value, the target location of the interface is changed.
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