公开(公告)号：US20200278369A1

公开(公告)日：2020-09-03

申请号：US15931282

申请日：2020-05-13

Applicant: GEN-PROBE INCORPORATED

Inventor： George T. WALKER ,  Matthias MERTEN ,  Gary D. LAIR

IPC: G01N35/10 ,  G01N35/04 ,  C12Q1/6806 ,  G01N35/00

Abstract: A conveyor assembly for transporting a carrier coupled to a receptacle to a processing station located within a housing of an instrument. The conveyor assembly includes a spur conveyor subassembly and a buffer conveyor subassembly for transporting the carrier from a host conveyor assembly to the spur conveyor subassembly. The spur conveyor subassembly includes (i) a rotatable diverter having at least one recess for receiving and moving the carrier between the buffer conveyor subassembly and the spur conveyor subassembly and (ii) a gripper configured to grasp the carrier and move it from the diverter to the processing position located within the housing of the instrument.

公开(公告)号：US20240069054A1

公开(公告)日：2024-02-29

申请号：US18504323

申请日：2023-11-08

Applicant: GEN-PROBE INCORPORATED

Inventor： George T. WALKER ,  Matthias MERTEN ,  Gary D. LAIR

IPC: G01N35/10 ,  C12Q1/6806 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N35/1011 ,  C12Q1/6806 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/04 ,  G01N35/1065 ,  G01N2035/00742 ,  G01N2035/00782 ,  G01N2035/00801 ,  G01N2035/0406 ,  G01N2035/046 ,  G01N2035/0462 ,  G01N2035/0465 ,  G01N2035/0467 ,  G01N2035/047 ,  G01N2035/0472

Abstract: An automated conveyor assembly for transporting a carrier coupled to processing receptacle from (i) a carrier conveyor assembly to (ii) a processing position within an instrument, where the automated conveyor assembly includes a gripper configured to selectively grasp a carrier and move between (i) a first position and (ii) the processing position in the instrument. The automated conveyor assembly further includes a diverter defining a recess configured to receive a carrier, the diverter being rotatable between (i) a first position at which the recess is aligned with the carrier conveyor assembly and (ii) a second position at which the recess is aligned with the first position of the gripper.

公开(公告)号：US20240069053A1

公开(公告)日：2024-02-29

申请号：US18504013

申请日：2023-11-07

Applicant: GEN-PROBE INCORPORATED

Inventor： George T. WALKER ,  Matthias MERTEN ,  Gary D. LAIR

IPC: G01N35/10 ,  C12Q1/6806 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N35/1011 ,  C12Q1/6806 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/04 ,  G01N35/1065 ,  G01N2035/00742 ,  G01N2035/00782 ,  G01N2035/00801 ,  G01N2035/0406 ,  G01N2035/046 ,  G01N2035/0462 ,  G01N2035/0465 ,  G01N2035/0467 ,  G01N2035/047 ,  G01N2035/0472

Abstract: A conveyor assembly for transporting a carrier coupled to a receptacle to a processing station located within a housing of an instrument. The conveyor assembly includes a spur conveyor subassembly and a buffer conveyor subassembly for transporting the carrier from a host conveyor assembly to the spur conveyor subassembly. The spur conveyor subassembly includes (i) a rotatable diverter having at least one recess for receiving and moving the carrier between the buffer conveyor subassembly and the spur conveyor subassembly and (ii) a gripper configured to grasp the carrier and move it from the diverter to the processing position located within the housing of the instrument.

公开(公告)号：US20240077509A1

公开(公告)日：2024-03-07

申请号：US18388076

申请日：2023-11-08

Applicant: GEN-PROBE INCORPORATED

Inventor： George T. WALKER ,  Matthias MERTEN ,  Gary D. LAIR

IPC: G01N35/10 ,  C12Q1/6806 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N35/1011 ,  C12Q1/6806 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/04 ,  G01N35/1065 ,  G01N2035/00742 ,  G01N2035/00782 ,  G01N2035/00801 ,  G01N2035/0406 ,  G01N2035/046 ,  G01N2035/0462 ,  G01N2035/0465 ,  G01N2035/0467 ,  G01N2035/047 ,  G01N2035/0472

Abstract: A conveyor assembly for transporting a carrier coupled to a receptacle to a processing station located within a housing of an instrument. The conveyor assembly includes a spur conveyor subassembly and a buffer conveyor subassembly for transporting the carrier from a host conveyor assembly to the spur conveyor subassembly. The spur conveyor subassembly includes (i) a rotatable diverter having at least one recess for receiving and moving the carrier between the buffer conveyor subassembly and the spur conveyor subassembly and (ii) a gripper configured to grasp the carrier and move it from the diverter to the processing position located within the housing of the instrument.

公开(公告)号：US20170261431A1

公开(公告)日：2017-09-14

申请号：US15600245

申请日：2017-05-19

Applicant: GEN-PROBE INCORPORATED

Inventor： Gary D. LAIR ,  Thanh N. NGUYEN ,  Haitao LI ,  Florence LI ,  Byron J. KNIGHT ,  Robert E. HEINZ ,  Jerzy A. MACIOSZEK ,  Christopher B. DAVIS ,  Robert F. SCALESE

IPC: G01N21/64 ,  G01N35/02 ,  C12Q1/68 ,  G01N35/10 ,  G01N21/76 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N21/6428 ,  B01L7/52 ,  C12Q1/6813 ,  C12Q1/6851 ,  G01N21/6454 ,  G01N21/76 ,  G01N35/00693 ,  G01N35/0092 ,  G01N35/0098 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/028 ,  G01N35/04 ,  G01N35/1002 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6432 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2035/00346 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/0097 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0455 ,  G01N2035/0491 ,  G01N2035/103 ,  G01N2201/0415 ,  Y10S435/808 ,  Y10S435/809 ,  Y10T436/113332 ,  Y10T436/25 ,  C12Q2537/165

Abstract: A continuous process for performing multiple nucleic acid amplification assays, where at least a portion of a second subset of reaction mixtures are transferred to a heater while a first subset of reaction mixtures are being subjected to conditions for performing a nucleic acid amplification assay. During the process, a plurality of reaction mixtures from the first and second subsets of reaction mixtures are simultaneously subjected to conditions sufficient to perform multiple nucleic acid amplification assays in the reaction mixtures. The presence or absence of a target nucleic acid in the first subset of reaction mixtures is determined while the reaction mixtures are in the heater.

公开(公告)号：US20190049378A1

公开(公告)日：2019-02-14

申请号：US16014139

申请日：2018-06-21

Applicant: GEN-PROBE INCORPORATED

Inventor： Gary D. LAIR ,  Thanh N. NGUYEN ,  Haitao LI ,  Florence LI ,  Byron J. KNIGHT ,  Robert E. HEINZ ,  Jerzy A. MACIOSZEK ,  Christopher B. DAVIS ,  Robert F. SCALESE

IPC: G01N21/64 ,  G01N35/04 ,  G01N35/10 ,  C12Q1/6813 ,  C12Q1/6851 ,  G01N21/76 ,  G01N35/02 ,  G01N35/00 ,  B01L7/00

Abstract: A method of determining the presence or amount of a target nucleic acid in each of a plurality of reaction mixtures. In the method, a first plurality of reaction mixtures are provided to a heater and subjected to conditions for performing a first amplification reaction. The presence or amount of a first target nucleic acid in each of the first plurality of reaction mixtures is determined during the first amplification reaction. During the first amplification reaction, a second plurality of reaction mixtures are provided to the heater and subjected to conditions for performing a second amplification reaction. The presence or amount of a second target nucleic acid in each of the second plurality of reaction mixtures is determined during the second amplification reaction. At least a portion of the second plurality of reaction mixtures are removed from the heater during the second amplification reaction.

公开(公告)号：US20170254827A1

公开(公告)日：2017-09-07

申请号：US15434968

申请日：2017-02-16

Applicant: GEN-PROBE INCORPORATED

Inventor： George T. WALKER ,  Matthias MERTEN ,  Gary D. LAIR

IPC: G01N35/10 ,  G01N35/04 ,  C12Q1/68 ,  G01N35/00

CPC classification number: G01N35/1011 ,  C12Q1/6806 ,  G01N35/00732 ,  G01N35/00871 ,  G01N35/04 ,  G01N35/1065 ,  G01N2035/00742 ,  G01N2035/00782 ,  G01N2035/00801 ,  G01N2035/0406 ,  G01N2035/0462 ,  G01N2035/0467 ,  G01N2035/047 ,  G01N2035/0472

Abstract: A laboratory automated system can include a host conveyor assembly configured to transport a plurality of carriers and receptacles coupled thereto between at least a sample processing instrument and at least one assay instrument. The system includes an intermediate conveyor assembly configured to transport a plurality of carriers and receptacles coupled thereto from within sample processing instrument to the host conveyor assembly. The system also includes an intermediate conveyor assembly for each assay instrument configured to transport a plurality of carriers from host conveyor assembly to a respective processing position within the assay instrument. The intermediate conveyor assembly coupled to the assay instrument can include a buffer conveyor subassembly configured to receive carriers from the host conveyor assembly, and a spur conveyor assembly configured to transport a carrier to the processing position of the assay instrument.