Portable automated pipette for accurately pipetting and/or titrating
liquids
    1.
    发明授权
    Portable automated pipette for accurately pipetting and/or titrating liquids 失效
    便携式自动移液器,用于精确移液和/或滴定液体

    公开(公告)号:US4905526A

    公开(公告)日:1990-03-06

    申请号:US59644

    申请日:1987-06-08

    Abstract: A hand held self-contained automated pipette for portable operation having an electrically operated digital linear actuator. The actuator preferably includes a stepper motor driving a rotor. A threaded screw is coaxially positioned within the rotor and is connected to an actuator shaft having elongate grooves slidable in a guide for preventing shaft rotation so that precise linear motion is imparted to the shaft. A pipetting displacement assembly having one of various sizes is removably attached for actuation by a common actuator including programmed movement of a displacing piston in a displacement cylinder to optimize air interface volume, neutralize variations in vacuum pipette effects, and provide an accommodated stroke and readout for improved accuracy while pipetting and/or titrating different ranges of volumes. Upon calibration the piston undertakes immediate excursion to an end of travel limit and after motor slippage is retracted to a home position. This home position is chosen for optimum preservation of an air interface volume between drawn liquid and the piston tailored with particularity to the displacement assembly being used. Multiple precision modes, including pipetting, multiple dispensing, titration, dilution, and measurement, are provided. Other features are also disclosed.

    Abstract translation: 手持式独立自动移液器,用于便携式操作,具有电动数字线性致动器。 致动器优选地包括驱动转子的步进马达。 螺纹螺杆同轴地定位在转子内并且连接到致动器轴,致动器轴具有可在引导件中滑动的细长槽,用于防止轴旋转,从而将准确的线性运动施加到轴上。 具有各种尺寸之一的移液装置可移除地附接以用于通过公共致动器进行致动,该执行器包括位移缸中的置换活塞的编程移动,以优化空气界面体积,中和真空吸管效应的变化,并提供容纳的行程和读数 在吸取和/或滴定不同体积范围时提高准确度。 在校准后,活塞立即偏移到行程极限结束,并且电机滑动回缩到原始位置。 选择该起始位置是为了最佳地保持拉伸液体和活塞之间的空气界面体积,特别适用于所使用的位移组件。 提供了多种精确模式,包括移液,多次分配,滴定,稀释和测量。 还公开了其他特征。

    Pipette mechanism
    2.
    发明授权
    Pipette mechanism 失效
    移液器机构

    公开(公告)号:US4763535A

    公开(公告)日:1988-08-16

    申请号:US004864

    申请日:1987-01-20

    CPC classification number: B01L3/0224

    Abstract: A dashpot piston mounted in a closed chamber is coupled by an axially movable shaft to a pipette piston to regulate return movement of the pipette piston within a pipette cylinder to draw fluid into the cylinder. The dashpot shaft is movable within limits relative to the dashpot piston to accommodate a blow-out of residual fluid from the pipette by the shaft driving the pipette piston beyond a home position to blow residual fluid from the pipette cylinder. An air inlet port in the bottom of the chamber allows air to be drawn into the chamber with upward movement of the dashpot piston while a valve adjacent to the air inlet port opens in response to downward movement of the dashpot piston to exit air from the chamber. Control of the relative sizes of the air inlet port and valve outlet regulates the relative rates of upward and downward piston movement in the cylinder. The dashpot piston carries a movable plate of a variable capacitor transducer for monitoring the position of the pipette piston within the pipette cylinder.

    Abstract translation: 安装在封闭室中的缓冲器活塞通过可轴向移动的轴联接到移液管活塞,以调节移液管活塞在移液管气缸内的返回运动,以将流体吸入气缸。 缓冲器轴可相对于缓冲器活塞在极限内移动,以通过驱动移液管活塞的轴超过原始位置来容纳来自移液管的剩余流体的吹出,以吹送来自移液管的残余流体。 在室的底部的空气入口允许空气随着缓冲器活塞的向上运动而被吸入室中,同时与空气入口相邻的阀响应于缓冲器活塞向下移动以从腔室排出空气而打开 。 控制进气口和阀门出口的相对尺寸可调节气缸中上下活塞运动的相对速率。 缓冲器活塞承载可变电容换能器的可移动板,用于监测移液管活塞在移液管内的位置。

    Discharge lamp ballast
    3.
    发明授权
    Discharge lamp ballast 失效
    放电灯镇流器

    公开(公告)号:US4358712A

    公开(公告)日:1982-11-09

    申请号:US221095

    申请日:1980-12-29

    Abstract: Circuit for starting and operating a gas discharge lamp. The circuit includes a resonant circuit having a high Q during both starting and operating conditions of the lamp, thereby permitting a high lamp operating voltage to be obtained from a relatively low voltage power supply. The circuit comprises a power supply, an inductor-capacitor series-resonant circuit connected across the power supply terminals, and a lamp circuit connected in parallel with the capacitor of the series-resonant circuit, wherein the lamp circuit comprises a second capacitor connected in series with a gas discharge lamp.

    Abstract translation: 启动和操作气体放电灯的电路。 电路包括在灯的启动和运行条件期间具有高Q值的谐振电路,从而允许从相对低电压的电源获得高的灯工作电压。 该电路包括电源,连接在电源端子上的电感器 - 电容器串联谐振电路和与串联谐振电路的电容器并联连接的灯电路,其中灯电路包括串联连接的第二电容器 配有气体放电灯。

    Liquid chromatography pump
    4.
    发明授权
    Liquid chromatography pump 失效
    液相色谱泵

    公开(公告)号:US4180375A

    公开(公告)日:1979-12-25

    申请号:US913359

    申请日:1978-06-07

    Abstract: A fluid pump mechanism for delivering a smooth output of fluids to a system utilizing at least one piston in a chamber reciprocative therewithin. The piston has strokes that fill and empty the chamber in conjunction with the action of valve means located at the inlet and outlet of the chamber. Motive means causes reciprocation of the piston within the chamber. Control means is also included for minimizing the time during the piston cycle in which the piston is not emptying the chamber. The invention's scope also encompasses a pressure metering device for a fluid forcing means motivated by an electrical motor.

    Abstract translation: 一种流体泵机构,用于将流体的平滑输出输送到系统中,利用在其中在其中往复运动的腔室中的至少一个活塞。 活塞具有与腔室入口和出口处的阀装置的作用一起填充和排空室的冲程。 动力装置引起活塞在腔室内的往复运动。 还包括控制装置以最小化在活塞未排空的活塞循环期间的时间。 本发明的范围还包括用于由电动机驱动的流体强制装置的压力计量装置。

    Pipette device with tip ejector utilizing stored energy
    5.
    发明授权
    Pipette device with tip ejector utilizing stored energy 失效
    移液器装置,带顶端喷射器,利用储能

    公开(公告)号:US06871557B2

    公开(公告)日:2005-03-29

    申请号:US10304591

    申请日:2002-11-26

    CPC classification number: B01L3/0279

    Abstract: A pipette for use with a pipette tip to aspirate and dispense a quantity of liquid, comprising a housing, a pipette tip mounting shaft extending from the housing to receive a pipette tip, a pipette tip ejector mechanism for ejecting the pipette tip from the mounting shaft, energy storage means, means for storing energy in the energy storage means and means for releasing energy from the energy storage means to assist the tip ejector mechanism in the ejecting of the pipette tip from the mounting shaft.

    Abstract translation: 一种用于移液管吸头以吸取和分配一定量液体的移液器,包括一个外壳,一个从外壳延伸以接收移液管吸头的移液管末端安装轴,用于将移液管尖端从安装轴 能量存储装置,用于在能量存储装置中存储能量的装置和用于从能量存储装置释放能量的装置,以帮助尖端喷射器机构从安装轴喷射移液管尖端。

    Volume adjustable manual pipette with quick set volume adjustment
    6.
    发明授权
    Volume adjustable manual pipette with quick set volume adjustment 有权
    体积可调式手动移液器,可快速设定音量调节

    公开(公告)号:US06428750B1

    公开(公告)日:2002-08-06

    申请号:US09548439

    申请日:2000-04-13

    CPC classification number: B01L3/0224 Y10T436/2575

    Abstract: A volume adjustable manual pipette having a hand-holdable housing supporting (i) an electronic digital display and associated position sensing and control circuitry, (ii) a plunger unit and (iii) a quick set volume adjustment mechanism for simultaneously controlling the volume setting of the pipette and the electronic display, the quick set volume adjustment mechanism comprising a pipette volume setting member for limiting upward movement of the plunger unit within the housing to define the volume setting for the pipette and the volume setting member being supported for axial movement on the plunger unit and releasably secured relative to the housing by a pipette user operable locking mechanism. When released from the housing, the volume setting member is axially moveable on and with the plunger unit to quickly set the volume for the pipette. When secured to the housing, the plunger unit is axially moveable relative to the volume setting unit to aspirate and dispense the selected volume of liquid into and from a pipette tip extending from a lower end of the housing. The volume setting of the pipette is monitored by the sensing and control circuitry to provide a real time display of the volume setting of the pipette.

    Abstract translation: 一种体积可调节的手动移液器,其具有可手持的壳体,其支撑(i)电子数字显示器和相关联的位置感测和控制电路,(ii)柱塞单元和(iii)快速设定体积调节机构,用于同时控制 移液管和电子显示器,快速设定的体积调节机构包括用于限制柱塞单元在壳体内的向上运动的移液管体积调节构件,以限定用于移液管的体积设置,并且容积设定构件被支撑以在 柱塞单元,并通过移液管用户可操作的锁定机构相对于壳体可释放地固定。 当从壳体释放时,体积调节构件可以在柱塞单元上和与柱塞单元一起轴向移动以快速设定移液管的体积。 当固定到壳体时,柱塞单元相对于体积设定单元轴向移动,以将选定体积的液体吸入并分配到从壳体的下端延伸的移液管尖端和从其移出。 移液器的体积设置由感测和控制电路监控,以提供移液器的体积设置的实时显示。

    Disposable pipette tip
    8.
    发明授权
    Disposable pipette tip 失效
    一次性吸头

    公开(公告)号:US4748859A

    公开(公告)日:1988-06-07

    申请号:US22798

    申请日:1987-03-06

    CPC classification number: B01L3/0279

    Abstract: A disposable pipette tip member having three inner coaxial annular sealing bands spaced axially from an open proximal end for receiving a conical pipette tip mounting shaft. The first two sealing bands and adjacent valley regions of the tip member are relatively resilient and are shaped such that the two sealing bands simultaneously engage, guide and laterally support the pipette shaft as it enters the tip member to form annular fluid-tight seals with the shaft. The third band is relatively rigid and upon engagement with the shaft, forms a third annular fluid-tight seal and a controllable stop for the shaft such that the tip member is seated on the shaft adjacent the pipette tip ejector mechanism.

    Abstract translation: 一次性移液器吸头构件,其具有与开口近端轴向间隔开的三个内同轴环形密封带,用于容纳锥形吸头安装轴。 顶端构件的前两个密封带和相邻的谷区域是相对弹性的并且成形为使得当移液管进入尖端构件时,两个密封带同时接合,引导和横向地支撑移液管轴,以形成环形流体密封, 轴。 第三带相对刚性并且在与轴接合时形成第三环形流体密封和用于轴的可控止动件,使得尖端构件位于邻近移液管顶端喷射器机构的轴上。

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