公开(公告)号：US06828328B1

公开(公告)日：2004-12-07

申请号：US10087283

申请日：2002-03-01

Applicant: James Ellis ,  Fangming Zou

Inventor： James Ellis ,  Fangming Zou

IPC: A61K3144

CPC classification number: A61K31/34 ,  A61K31/16 ,  A61K31/19 ,  A61K31/415 ,  A61K31/44 ,  A61K2300/00

Abstract: This invention relates to the combination of muscarinic agonists with narcotic analgesics, non-steroidal anti-inflammatory drugs or other analgesic drugs and to their use as antinociception (pain relief) agents. In particular, the invention relates to a combination of a specific class of M4 selective muscarinic agonists with narcotic analgesics, non-steroidal anti-inflammatory drugs or other analgesic drugs.

Abstract translation: 本发明涉及毒蕈碱激动剂与麻醉止痛剂，非甾体抗炎药或其它镇痛药的组合，以及它们作为抗感冒药（止痛剂）的用途。 特别地，本发明涉及特定类型的M4选择性毒蕈碱激动剂与麻醉止痛剂，非甾体抗炎药或其它止痛药的组合。