Method for detecting a biomolecule by surface-enhanced Raman spectroscopy

    公开(公告)号:US11536664B2

    公开(公告)日:2022-12-27

    申请号:US17705325

    申请日:2022-03-27

    Abstract: The method for detecting a biomolecule by surface-enhanced Raman spectroscopy is a spectroscopic method of detecting a virus in a biological sample. A target substrate is prepared by depositing nanoparticles of a metal on a substrate of silicon nanowires. The nanoparticles may be gold, silver or a combination thereof. The far-field Raman spectra of at least one biomolecule associated with the virus are obtained. The biological fluid sample to be tested is then applied on the target substrate, and the surface-enhanced Raman spectroscopy spectra of the biological fluid sample on the target substrate are obtained. The far-field Raman spectra of the at least one biomolecule are compared against the surface-enhanced Raman spectroscopy spectra of the biological fluid sample on the target substrate.

    Device for monitoring internal pipe deposit accumulation

    公开(公告)号:US11815351B1

    公开(公告)日:2023-11-14

    申请号:US18210253

    申请日:2023-06-15

    CPC classification number: G01B7/085 G01N17/008 G01N27/22

    Abstract: The device for monitoring internal pipe deposit accumulation is a capacitance-based sensor for monitoring changes in thickness of deposits accumulating on an internal surface of a pipe. The device includes a pipe segment having opposed first and second open ends with at least one valve releasably sealing at least one of the first and second open ends. A first electrode, in the form of an electrically conductive cylindrical shell, is mounted on and surrounds a portion of an external surface of the pipe segment. A second electrode, in the form of an electrically conductive rod, is mounted coaxially within an interior of the pipe segment. An electrical power source is electrically connected across the first and second electrodes to form a cylindrical capacitor and changes in capacitance of the cylindrical capacitor are monitored by a controller.

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