公开(公告)号：US20130083206A1

公开(公告)日：2013-04-04

申请号：US13594329

申请日：2012-08-24

Applicant: Kazuhiro MAKINO ,  Jun TAKABA ,  Yasutake TANAKA

Inventor： Kazuhiro MAKINO ,  Jun TAKABA ,  Yasutake TANAKA

IPC: H04N5/217 ,  H04N5/225

CPC classification number: H04N5/37213 ,  H04N5/347 ,  H04N5/357 ,  H04N5/378

Abstract: An imaging apparatus is provided with a control unit, a noise reduction processing unit and a pixel value calculation unit. The control unit controls pulse widths of horizontal synchronization signals outputted to an imaging device such that a feed-through period and a signal period, in a case in which pixel addition in the horizontal direction is performed at the imaging device and imaging signals are outputted, are longer than a feed-through period and a signal period, in a case in which pixel addition in the horizontal direction is not performed at the imaging device. The noise reduction processing unit executes noise reduction processing to reduce the effects of noise produced in the imaging signals. The pixel value calculation unit calculates a pixel value on the basis of a first signal sampled in the feed-through period and a second signal sampled in the signal period.

Abstract translation: 成像装置具有控制单元，降噪处理单元和像素值计算单元。 控制单元控制输出到成像装置的水平同步信号的脉冲宽度，使得在成像装置处执行水平方向的像素相加和成像信号的情况下，馈送周期和信号周期被输出， 在成像装置不进行水平方向的像素相加的情况下，比馈通周期和信号周期长。 噪声降低处理单元执行降噪处理以减少在成像信号中产生的噪声的影响。 像素值计算单元基于在馈通周期中采样的第一信号和在信号周期中采样的第二信号来计算像素值。

公开(公告)号：US20120298885A1

公开(公告)日：2012-11-29

申请号：US13478958

申请日：2012-05-23

Applicant: Seishi IKAMI ,  Kazuhiro MAKINO

Inventor： Seishi IKAMI ,  Kazuhiro MAKINO

IPC: G01J1/58 ,  G01J3/50

CPC classification number: G01N21/6456 ,  G01N21/6428 ,  G01N2021/6419 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2201/0627

Abstract: A fluorometric assay apparatus comprising an LED light source configured with at least two types of excitation LED that have different principle wavelengths from each other and are disposed in a two dimensional array on a substrate; an imaging lens for imaging a subject; a single excitation filter provided between the LED light source and a subject, the single excitation filter transmitting each of principle wavelength components of the LED light source; and a single detection long pass filter provided between the imaging lens and the subject.

Abstract translation: 一种荧光测定装置，包括配置有至少两种类型的激发LED的LED光源，所述至少两种激发LED具有彼此不同的原理波长并且以基板上的二维阵列设置; 用于成像对象的成像镜头; 设置在所述LED光源和被摄体之间的单个激发滤光器，所述单个激发滤光器传输所述LED光源的各个主要波长分量; 以及设置在成像透镜和被摄体之间的单个检测长通滤波器。

公开(公告)号：US20120249862A1

公开(公告)日：2012-10-04

申请号：US13422687

申请日：2012-03-16

Applicant: Kazuhiro MAKINO

Inventor： Kazuhiro MAKINO

IPC: H04N5/235

CPC classification number: G01N21/6452 ,  G01N21/253 ,  G01N21/6456 ,  G03B7/28 ,  G03B15/07 ,  H04N5/2351 ,  H04N5/2354

Abstract: There is provided an imaging device that has: light source elements that illuminate a subject; an image pick-up element that picks-up an image of the subject; storage unit that stores relationships of correspondence between the light source elements and regions that are illuminated by the light source elements respectively; pre-exposure unit that lights all of the light source elements and pre-exposing the subject; specifying unit that, on the basis of a pre-exposure image of the subject that is picked-up by the image pick-up element due to the pre-exposure, specifies a saturated region that is saturated when exposed for an exposure time of actual exposure; and actual exposure unit for, on the basis of the relationships of correspondence, specifies a light source element that corresponds to the saturated region, and carries out actual exposure by shortening a lighting time of the specified light source element.

Abstract translation: 提供了一种成像装置，其具有：照射被摄体的光源元件; 拾取所述被摄体的图像的图像拾取元件; 存储单元，其分别存储光源元件和由光源元件照明的区域之间的对应关系; 预曝光单元，照亮所有光源元件并预曝光对象; 指定单元，其基于由所述预曝光而由所述图像拾取元件拾取的被摄体的预曝光图像，指定在实际暴露时间曝光时饱和的饱和区域 曝光; 并且根据对应关系的实际曝光单元指定对应于饱和区域的光源元件，并通过缩短指定光源元件的点亮时间来进行实际曝光。

公开(公告)号：US20110228143A1

公开(公告)日：2011-09-22

申请号：US13013202

申请日：2011-01-25

Applicant: Kazuhiro MAKINO

Inventor： Kazuhiro MAKINO

IPC: H04N9/64 ,  H04N5/335

CPC classification number: H04N5/357 ,  G01N21/6456 ,  G01N21/76 ,  G01N2201/0231 ,  H04N5/2173 ,  H04N5/2353

Abstract: In an imaging device, a cooling unit cools an imaging element. A storage unit stores table data representing correspondence relationships between signal values based on luminescences of detection targets, cooling temperatures, exposure times, and S/N ratios. A S/N calculating unit calculates a S/N ratio at a time when pre-imaging has been performed. A determination unit determines, from the table data and as a cooling temperature and an exposure time for the imaging, a combination of a cooling temperature and an exposure time with which the S/N ratio becomes equal to or greater than the reference S/N ratio on the basis of a result of comparison between the calculated S/N ratio and a predetermined reference S/N ratio. A control unit controls the imaging element and the cooling element such that a subject is imaged at the cooling temperature and in the exposure time that are determined.

Abstract translation: 在成像装置中，冷却单元冷却成像元件。 存储单元存储表示基于检测对象的发光度，冷却温度，曝光时间和S / N比的信号值之间的对应关系的表格数据。 S / N计算单元计算在执行预成像时的S / N比。 确定单元从表格数据和用于成像的冷却温度和曝光时间确定S / N比等于或大于参考S / N的冷却温度和曝光时间的组合 基于所计算的S / N比与预定参考S / N比的比较结果的比率。 控制单元控制成像元件和冷却元件，使得被摄体在冷却温度和确定的曝光时间内成像。