公开(公告)号：US11198878B2

公开(公告)日：2021-12-14

申请号：US17006675

申请日：2020-08-28

Applicant: Labcyte Inc.

Inventor： Jennifer M. Hardee ,  Richard N. Ellson ,  Richard G. Stearns ,  Babur Hadimioglu ,  Joseph D. Olechno ,  Marsha N. Blauwkamp

IPC: C07H21/04 ,  C12N15/64 ,  C12N15/87 ,  A61N7/00 ,  C12N9/22 ,  C12N13/00 ,  C12N15/11

Abstract: A method is provided for achieving transfection of host cells using sonoporation. An acoustic radiation generator is positioned in acoustic coupling relationship with respect to a reservoir containing host cells to be transfected, exogenous material to be incorporated into the host cells, and a cell-compatible fluid medium. The acoustic radiation generator is activated to generate acoustic radiation and direct the acoustic radiation into the reservoir in a manner effective to enable transfection of the host cells with the exogenous material.

公开(公告)号：US10787670B2

公开(公告)日：2020-09-29

申请号：US15706524

申请日：2017-09-15

Applicant: Labcyte Inc.

Inventor： Jennifer M. Hardee ,  Richard N. Ellson ,  Richard G. Stearns ,  Babur Hadimioglu ,  Joseph D. Olechno ,  Marsha N. Blauwkamp

IPC: C07H21/04 ,  C12N15/64 ,  C12N15/87 ,  A61N7/00 ,  C12N9/22 ,  C12N13/00 ,  C12N15/11

Abstract: A method is provided for achieving transfection of host cells using sonoporation. An acoustic radiation generator is positioned in acoustic coupling relationship with respect to a reservoir containing host cells to be transfected, exogenous material to be incorporated into the host cells, and a cell-compatible fluid medium. The acoustic radiation generator is activated to generate acoustic radiation and direct the acoustic radiation into the reservoir in a manner effective to enable transfection of the host cells with the exogenous material.

公开(公告)号：US20180073029A1

公开(公告)日：2018-03-15

申请号：US15706524

申请日：2017-09-15

Applicant: Labcyte Inc.

Inventor： Jennifer M. Hardee ,  Richard N. Ellson ,  Richard G. Stearns ,  Babur Hadimioglu ,  Joseph D. Olechno ,  Marsha N. Blauwkamp

IPC: C12N15/64 ,  C12N13/00 ,  C12N15/11 ,  C12N9/22

Abstract: A method is provided for achieving transfection of host cells using sonoporation. An acoustic radiation generator is positioned in acoustic coupling relationship with respect to a reservoir containing host cells to be transfected, exogenous material to be incorporated into the host cells, and a cell-compatible fluid medium. The acoustic radiation generator is activated to generate acoustic radiation and direct the acoustic radiation into the reservoir in a manner effective to enable transfection of the host cells with the exogenous material.

公开(公告)号：US20220025382A1

公开(公告)日：2022-01-27

申请号：US17497792

申请日：2021-10-08

Applicant: Labcyte Inc.

Inventor： Jennifer M. Hardee ,  Richard N. Ellson ,  Richard G. Stearns ,  Babur Hadimioglu ,  Joseph D. Olechno ,  Marsha N. Blauwkamp

IPC: C12N15/64 ,  C12N15/87 ,  A61N7/00 ,  C12N9/22 ,  C12N13/00 ,  C12N15/11

Abstract: A method is provided for achieving transfection of host cells using sonoporation. An acoustic radiation generator is positioned in acoustic coupling relationship with respect to a reservoir containing host cells to be transfected, exogenous material to be incorporated into the host cells, and a cell-compatible fluid medium. The acoustic radiation generator is activated to generate acoustic radiation and direct the acoustic radiation into the reservoir in a manner effective to enable transfection of the host cells with the exogenous material.