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公开(公告)号:US20220125301A1
公开(公告)日:2022-04-28
申请号:US17424056
申请日:2020-03-19
Applicant: Leica Microsystems Inc.
Inventor: Robert H. Hart , Dorothy M. Branco , Eric L. Buckland , Micaela R. Mendlow
Abstract: Systems for determining an apex of curvature In an image, obtained from, a sample are provided. The systems include—an imaging system configured to obtain a plurality of scans of a sample using a radial pattern; and a processor associated with the imaging system. The processor is configured to segment and curve fit each of the plurality of scans to a surface of the sample; determine an apex. for each curve associated with each of the plurality of scans; determine a true apex, among all determined apexes using a derivative of least value; calculate an XY offset based on the determined true apex; map the true apex to an origin where X and Y are equal to zero; and adjust the coordinates associated with remaining apexes not determined to be the true apex based on the calculated offset.
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2.
公开(公告)号:US20190200854A1
公开(公告)日:2019-07-04
申请号:US15860707
申请日:2018-01-03
Applicant: Leica Microsystems Inc.
Inventor: Andrew Murnan , Nestor O. Farmiga , Christopher Saxer , Al-Hafeez Z. Dhalla , Eric L. Buckland , Robert H. Hart
CPC classification number: A61B3/0025 , A61B3/102 , G09B23/22 , G09B23/30
Abstract: A model eye for use with an imaging system is provided. The model eye includes a shape that mimics a shape of a real eye of a subject and focal parameters of the real eye of the subject. The model eye is positioned in the imaging system in place of the real eye to assess and/or calibrate the imaging system. Related methods, systems and devices are also provided herein.
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