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公开(公告)号：US20180008687A1
公开(公告)日：2018-01-11
申请号：US15584516
申请日：2017-05-02
Applicant: Massachusetts Institute of Technology
Inventor： Paiman Peter Ghoroghchian , Ruogu Qi , Angela M. Belcher , Xiangnan Dang , Zhimin Tao
Abstract: Disclosed are methods of treating cancer of the intraperitoneal cavity using compositions comprising nanoparticles without targeting agents. In addition, nanoparticles are described that comprise a highly toxic anticancer agent (e.g., an anticancer agent having an IC50 less than 1 nM) covalently bound via a linker to a triblock copolymer. Other nanoparticles that comprise Pt(IV) and an anticancer agent are also described. Also disclosed are nanoparticles comprising imaging agents non-covalently associated with a polymer, and methods of imaging cancer of the intraperitoneal cavity using compositions comprising nanoparticles without targeting agents.
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公开(公告)号：US10276309B2
公开(公告)日：2019-04-30
申请号：US14434098
申请日：2013-10-08
Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor： Jifa Qi , Xiangnan Dang , Angela M. Belcher , Paula T. Hammond
Abstract: A dye-sensitized solar cell can include a plurality of a plasmon-forming nanostructures. The plasmon-forming nanostructures can include an oxide core, an inner metallic shell on a surface of the oxide core, and an outer oxide shell on a surface of the inner metallic shell.
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Patent Agency Ranking
公开(公告)号：US20150262760A1
公开(公告)日：2015-09-17
申请号：US14434098
申请日：2013-10-08
Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventor： Jifa Qi , Xiangnan Dang , Angela M. Belcher , Paula T. Hammond
CPC classification number: H01G9/209 , B82Y20/00 , B82Y40/00 , H01G9/0029 , H01G9/2027 , H01G9/2031 , H01G9/2036 , Y02E10/542 , Y02P70/521 , Y10S977/89 , Y10S977/948
Abstract: A dye-sensitized solar cell can include a plurality of a plasmon-forming nanostructures. The plasmon-forming nanostructures can include an oxide core, an inner metallic shell on a surface of the oxide core, and an outer oxide shell on a surface of the inner metallic shell.
Abstract translation: 染料敏化太阳能电池可以包括多个等离子体激发形成纳米结构。 等离子体激发形成纳米结构可以包括氧化物核，氧化物核的表面上的内部金属壳和内部金属壳的表面上的外部氧化物壳。
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公开(公告)号：US10751423B2
公开(公告)日：2020-08-25
申请号：US15584516
申请日：2017-05-02
Applicant: Massachusetts Institute of Technology
Inventor： Paiman Peter Ghoroghchian , Ruogu Qi , Angela M. Belcher , Xiangnan Dang , Zhimin Tao
IPC: A61K9/00 , A61K48/00 , A61K47/60 , A61K47/64 , A61K47/69 , A61K31/555 , A61K33/24 , C08G81/00 , C12N15/11 , A61K9/107 , A61K31/282 , A61K47/34 , C07K2/00 , C08G69/10 , C12N15/90 , A61K39/00 , A61K47/10 , C12N15/09 , G01N21/47
Abstract: Disclosed are methods of treating cancer of the intraperitoneal cavity using compositions comprising nanoparticles without targeting agents. In addition, nanoparticles are described that comprise a highly toxic anticancer agent (e.g., an anticancer agent having an IC50 less than 1 nM) covalently bound via a linker to a triblock copolymer. Other nanoparticles that comprise Pt(IV) and an anticancer agent are also described. Also disclosed are nanoparticles comprising imaging agents non-covalently associated with a polymer, and methods of imaging cancer of the intraperitoneal cavity using compositions comprising nanoparticles without targeting agents.
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公开(公告)号：US20180042483A1
公开(公告)日：2018-02-15
申请号：US15558162
申请日：2016-03-07
Applicant: Massachusetts Institute of Technology
Inventor： Neelkanth M. Bardhan , Xiangnan Dang , Jifa Qi , Angela M. Belcher
CPC classification number: A61B5/0071 , A61B5/0075 , A61B5/0091 , A61B5/7232 , A61B2576/00 , A61B2576/02 , G01J3/0213 , G01J3/18 , G01J3/2823 , G01J3/32 , G01J3/36 , G01J3/4406 , G01N21/64 , G01N33/22 , G01N2021/6421 , G01N2201/12 , G02B21/361
Abstract: A method, and corresponding system, can include identifying a plurality of wavelength spectral band components in hyperspectral image data, the spectral band components corresponding to mutually distinct sources of image contrast. An intensity image corresponding to each respective spectral band component can be calculated, followed by combining the respective intensity images to form an inter-band image based on the respective, mutually distinct sources of image contrast for each spectral band component. Intensity images can be hyperspectral or hyperdiffuse images. Hyperdiffuse imaging can be performed for each spectral band component identified using hyperspectral measurements. Spectral position and spectral width images corresponding to each spectral band component can be calculated and used to determine depth of features inside a surface of the target. Diffuse width images can be calculated from hyperdiffuse image data and used to determine depth.
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公开(公告)号：US09082554B2
公开(公告)日：2015-07-14
申请号：US13914253
申请日：2013-06-10
Applicant: Massachusetts Institute of Technology
Inventor： Xiangnan Dang , Hyunjung Yi , Angela M. Belcher , Paula T. Hammond
CPC classification number: H01G9/2059 , B82Y10/00 , B82Y30/00 , B82Y40/00 , C01B32/174 , C12N2795/14131 , H01L51/0049 , H01L51/0093 , H01L51/426 , Y02E10/542 , Y02E10/549 , Y02P70/521
Abstract: A method of a general biological approach to synthesizing compact nanotubes using a biological template is described.
Abstract translation: 描述了使用生物模板合成紧凑型纳米管的一般生物学方法。
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公开(公告)号：US20140000688A1
公开(公告)日：2014-01-02
申请号：US13914253
申请日：2013-06-10
Applicant: Massachusetts Institute of Technology
Inventor： Xiangnan Dang , Hyunjung Yi , Angela M. Belcher , Paula T. Hammond
IPC: H01G9/20
CPC classification number: H01G9/2059 , B82Y10/00 , B82Y30/00 , B82Y40/00 , C01B32/174 , C12N2795/14131 , H01L51/0049 , H01L51/0093 , H01L51/426 , Y02E10/542 , Y02E10/549 , Y02P70/521
Abstract: A method of a general biological approach to synthesizing compact nanotubes using a biological template is described.
Abstract translation: 描述了使用生物模板合成紧凑型纳米管的一般生物学方法。
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