公开(公告)号：US20240053372A1

公开(公告)日：2024-02-15

申请号：US18268423

申请日：2021-12-20

Applicant: Merck Patent GmbH

Inventor： Stephane OLIVIER ,  Gaetan BOUR

IPC: G01N35/10 ,  G01N35/00

CPC classification number: G01N35/1002 ,  G01N35/00732 ,  G01N2035/00752

Abstract: System for performing a media preparation process controlled by a computer (7) further comprising a Media Preparation Module (12), a media bag (2) for storing the media in an unprepared state (13), a Dispensing Module (9, 9a) for storing the media in a finally prepared state (17), and a water providing system which connects the Media Preparation Module (12) with the media bag (2) and the Dispensing Module (9, 9a) and provides them with temperature adjustable water using a water sterilization filter set (4) wherein, the system (6) additionally comprises an attachable machine readable data storage (3) which contains information about the current state and/or operating parameters of the system parts, which are read, processed and used by the computer (7) to operate the system (6) according to required conditions.

公开(公告)号：US20210024865A1

公开(公告)日：2021-01-28

申请号：US17040460

申请日：2019-03-20

Applicant: Merck Patent GmbH

Inventor： Stephane OLIVIER ,  Gaetan BOUR

IPC: C12M1/00 ,  C12M1/34

Abstract: The invention provides a system for observation of media dissolution and/or bacterial growth in a transparent bag, comprising a receptacle for supporting the bag, and a light emitting device arranged to transmit light into and/or through the interior of the bag supported at the receptacle. The media in the transparent bag can be visually inspected to confirm the dissolution state of the media and check for residual undissolved media and/or confirm the absence of unexpected microbial growth without having to move or handle the bag as it can remain supported in a defined orientation at the receptacle during repeated visual inspections by means of the light emitted from the light emitting device

公开(公告)号：US20170051331A1

公开(公告)日：2017-02-23

申请号：US15307541

申请日：2015-03-31

Applicant: Merck Patent GmbH

Inventor： Stephane OLIVIER

IPC: C12Q1/22 ,  C12M1/00 ,  G01N1/40 ,  C12M1/12

CPC classification number: C12Q1/22 ,  A61L2/28 ,  B01L3/502 ,  B01L2200/0684 ,  B01L2200/141 ,  B01L2300/042 ,  B01L2400/0457 ,  B01L2400/0478 ,  C12M23/34 ,  C12M23/38 ,  C12M25/02 ,  G01N1/4077 ,  G01N2001/4088

Abstract: A sample preparation device comprising a first chamber containing a first movable piston separating a first volume upstream and a second volume downstream the first piston, a second chamber containing a second movable piston separating a third volume upstream and a fourth volume downstream the second piston, and an inlet to the first volume and an outlet from the first volume. The first volume is connected with the third volume by a first communication path and the second volume is connected with the fourth volume by a second communication path.

Abstract translation: 一种样品制备装置，包括第一室，所述第一室包含分隔第一活塞上游的第一容积和在第一活塞下游的第二体积的第一活塞;第二室，包含分隔第二活塞下游的第三体积上游和第四体积的第二可移动活塞; 第一容积的入口和来自第一容积的出口。 第一卷通过第一通信路径与第三卷连接，第二卷通过第二通信路径与第四卷连接。

公开(公告)号：US20170021355A1

公开(公告)日：2017-01-26

申请号：US15301207

申请日：2015-03-09

Applicant: MERCK PATENT GMBH

Inventor： Stephane OLIVIER ,  Luc FELDEN ,  Didier METZ

IPC: B01L3/00 ,  G01N1/38

Abstract: A fluid transfer device comprising a first reservoir (1) having a predetermined sub-ambient pressure and volume and a presealed opening (1a), a second reservoir (2) containing a predetermined volume of a fluid (M) and having a presealed opening (2a), and a chamber (3) having an internal space (6) and an inlet (4) to the space (6) adapted to be connected to the opening (2a) of the second reservoir (2) and an outlet (5) from the space (6) adapted to be connected to the opening (1a) of the first reservoir (1).

Abstract translation: 一种流体输送装置，包括具有预定的次环境压力和体积的第一储存器（1）和预先存在的开口（1a），包含预定体积的流体（M）的第二储存器（2） 2a）和具有适于连接到第二储存器（2）的开口（2a）的空间（6）的内部空间（6）和入口（4）的室（3）和出口（5） ）适于连接到第一储存器（1）的开口（1a）的空间（6）。

公开(公告)号：US20230390756A1

公开(公告)日：2023-12-07

申请号：US18032878

申请日：2021-10-20

Applicant: Merck Patent GmbH

Inventor： Stephane OLIVIER

IPC: B01L1/02 ,  A61L2/26 ,  B01L1/04 ,  B01L9/00 ,  C12M3/00 ,  C12M1/00 ,  C12M1/12

CPC classification number: B01L1/025 ,  A61L2/26 ,  B01L1/04 ,  B01L9/52 ,  C12M23/48 ,  C12M23/52 ,  C12M37/00 ,  B01L2200/025 ,  B01L2200/141 ,  B01L2300/0609 ,  B01L2300/0832

Abstract: Transfer mechanism/device (40) transferring one or more objects (O) through a transfer port (R), having a supporting base (41), a shuttle (42) with a mount (43) for a holder (47) for the one or more objects (O) or with a holder (47) and a container (44) accommodating the base (41) and the shuttle (42) and accommodating the objects (O), and having at least one opening (45) at an end portion in an axial direction (X) of the container (44).

公开(公告)号：US20210229051A1

公开(公告)日：2021-07-29

申请号：US17259444

申请日：2019-07-10

Applicant: MERCK PATENT GMBH

Inventor： Stephane OLIVIER ,  Gaetan BOUR

IPC: B01F11/00 ,  B01F15/00

Abstract: A mixing device (1) for cyclically imparting a force on an external surface (A) of a bag (B) for agitating a content (C) of the bag (B), the mixing device (1) comprising a lever (2) supported so as to be able to pivot about a pivot (3), a weight (4) provided on a first side of the lever (2), a driver (5) arranged to cooperate with the lever (2), a motor (6) for moving the driver (5) to lift the first side of the lever (2) with the weight (4) against gravity and to drop the first side against the external surface (A) of the bag (B), and a holder (7) for supporting the mixing device (1) such that the first side of the lever (2) can contact the external surface (A) of the bag (B) in the drop motion.

公开(公告)号：US20180318772A1

公开(公告)日：2018-11-08

申请号：US15779343

申请日：2016-11-04

Applicant: MERCK PATENT GMBH

Inventor： Stephane OLIVIER ,  Didier METZ

IPC: B01D69/10 ,  C12M1/12 ,  A61L2/28 ,  C12Q1/22

CPC classification number: B01D69/10 ,  A61L2/28 ,  B01D61/14 ,  B01D69/06 ,  B01D2313/12 ,  B01L3/00 ,  B01L2200/10 ,  C12M25/02 ,  C12M37/02 ,  C12Q1/22

Abstract: A membrane support, usable for example in a membrane filtration device, comprises a support surface provided on an upstream side of the membrane support and adapted to support a flat filtration membrane thereon, and a drainage structure arranged below the support surface to collect a fluid that has passed the filtration membrane supported on the support surface and guide the fluid away to a downstream side, wherein the support surface has a plurality of recesses distributed over the support surface and formed to absorb expansions of the filtration membrane. The membrane support avoids fold formation of a membrane due to membrane expansion after hydration.

公开(公告)号：US20230390780A1

公开(公告)日：2023-12-07

申请号：US18032913

申请日：2021-10-20

Applicant: Merck Patent GmbH

Inventor： Stephane OLIVIER

IPC: B01L9/00

CPC classification number: B01L9/52 ,  B01L2200/18

Abstract: The present application relates to a rack (1) for holding a plurality of petri-dishes (P), comprising a plate-like main body (2) with a plurality of adjacent and spaced apart holding portions (3) each configured to receive and support, in a substantially horizontal orientation that is substantially perpendicular to a plane of the plate-like main body (2), a petri-dish (P), wherein each holding portion (3) includes positioning features (4) for positioning the petri-dish (P) in the holding portion (3).

公开(公告)号：US20230285978A1

公开(公告)日：2023-09-14

申请号：US18032883

申请日：2021-10-20

Applicant: Merck Patent GmbH

Inventor： Stephane OLIVIER

IPC: B01L9/00

CPC classification number: B01L9/523

Abstract: The present application relates to a rack (1) for holding a plurality of petri-dishes (P), comprising a main body (2) with a plurality of adjacent and spaced apart holding portions (3) each configured to receive and support, in a substantially parallel orientation that is substantially perpendicular to a longitudinal direction (X) of the rack (1), a petri-dish (P), wherein each holding portion (3) includes positioning features (4) for positioning the petri-dish (P) in the holding portion (3) and allowing insertion of the petri-dish (P) from a lateral side in a direction substantially perpendicular to the longitudinal direction (X). The holding portions (3) and positioning features (4) respectively comprise a pair of separation elements (11) spaced apart from each other to define therebetween a slot (12) configured to receive the petri-dish (P).

公开(公告)号：US20220249827A1

公开(公告)日：2022-08-11

申请号：US17613524

申请日：2020-05-27

Applicant: Merck Patent GmbH

Inventor： Stephane OLIVIER ,  Gaelle SCHMITT ,  Gaetan BOUR

IPC: A61M39/26

Abstract: A holding device (1) for automated stopcock actuation, comprising a base body (2); and a driver (3) rotatably received at the base body (2). The holding device (1) has a receptacle (4) for removably receiving at least a part of a stopcock (A) and is configured such that the driver (3) can engage with and actuate a handle (B) of the stopcock (A) received in the receptacle (4) upon rotation of the driver (3), and a first fixation member (5) that is configured to allow selective fixation of the stopcock (A) in the receptacle (4).