公开(公告)号：US11896840B2

公开(公告)日：2024-02-13

申请号：US18060073

申请日：2022-11-30

Applicant: NORTHWESTERN UNIVERSITY

Inventor： Shuai Xu ,  Chenkai Xu ,  Hao Zhang ,  Hangbo Zhao ,  John A. Rogers

IPC: A61N5/06 ,  A61M37/00

CPC classification number: A61N5/0601 ,  A61M37/0015 ,  A61N5/062 ,  A61M2037/003 ,  A61M2037/0061 ,  A61N2005/0602 ,  A61N2005/063 ,  A61N2005/0652 ,  A61N2005/0661

Abstract: Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device comprises a tissue penetrating member having a distal end and a proximal end, the tissue penetrating member configured to penetrate the tissue of the patient to be inserted into the tissue, wherein the tissue penetrating member is at least partially optically transparent along a surface of the tissue penetrating member positioned between the distal end of the tissue penetrating member and the proximal end of the tissue penetrating member to provide optical transmission of at least a portion of the light through the surface of the tissue penetrating member, thereby allowing at least the portion of the light to be delivered into the tissue of the patient when the tissue penetrating member is inserted into the tissue; and a substrate that supports the tissue penetrating member.

公开(公告)号：US11571586B2

公开(公告)日：2023-02-07

申请号：US17056094

申请日：2019-05-17

Applicant: NORTHWESTERN UNIVERSITY

Inventor： Shuai Xu ,  Chenkai Xu ,  Hao Zhang ,  Hangbo Zhao ,  John A. Rogers

IPC: A61N5/06 ,  A61M37/00

Abstract: Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device may comprise a microarray of tissue penetrating members, each member having a distal end and a proximal end, wherein the tissue penetrating members are at least partially optically transparent to provide optical transmission through a surface that extends between the distal and proximal ends of each tissue penetrating member and a substrate that supports the tissue penetrating members, wherein the substrate is optionally a flexible substrate.