公开(公告)号：US20210364421A1

公开(公告)日：2021-11-25

申请号：US17303995

申请日：2021-06-11

Applicant: NUEON INC.

Inventor： Robert G. MESSERSCHMIDT ,  Howland D. T. JONES

IPC: G01N21/27 ,  G01N33/49 ,  G01N21/59 ,  A61B5/00 ,  A61B5/02

Abstract: Biomarkers of high blood pressure are measured to identify high blood pressure of the subject based on one or more biomarkers. In many embodiments, the response of the biomarker to blood pressure occurs over the course of at least an hour, such that the high blood pressure identification is based on a cumulative effect of physiology of the subject over a period of time. The methods and apparatus of identifying high blood pressure with biomarkers have the advantage of providing improved treatment of the subject, as the identified biomarker can be related to an effect of the high blood pressure on the subject, such as a biomarker corresponding to central blood pressure. The sample can be subjected to increases in one or more of pressure or temperatures, and changes in the blood sample measured over time.

公开(公告)号：US20170350814A1

公开(公告)日：2017-12-07

申请号：US15620269

申请日：2017-06-12

Applicant: NUEON INC.

Inventor： Robert G. MESSERSCHMIDT ,  Howland D. T. JONES

IPC: G01N21/27 ,  A61B5/00 ,  G01N33/49 ,  G01N21/59 ,  A61B5/02

CPC classification number: G01N21/27 ,  A61B5/0075 ,  A61B5/02 ,  A61B5/4833 ,  G01N21/59 ,  G01N33/492 ,  G01N2201/06113 ,  G01N2201/068

Abstract: Biomarkers of high blood pressure are measured to identify high blood pressure of the subject based on one or more biomarkers. In many embodiments, the response of the biomarker to blood pressure occurs over the course of at least an hour, such that the high blood pressure identification is based on a cumulative effect of physiology of the subject over a period of time. The methods and apparatus of identifying high blood pressure with biomarkers have the advantage of providing improved treatment of the subject, as the identified biomarker can be related to an effect of the high blood pressure on the subject, such as a biomarker corresponding to central blood pressure. The sample can be subjected to increases in one or more of pressure or temperatures, and changes in the blood sample measured over time.