公开(公告)号：US20220135748A1

公开(公告)日：2022-05-05

申请号：US17219915

申请日：2021-04-01

Applicant: National Taiwan University of Science and Technology

Inventor： Hsieh-Chih TSAI ,  Shuian-Yin LIN ,  Hsiao-Ying CHOU

IPC: C08J3/075 ,  C08J3/24 ,  A61L26/00

Abstract: The present disclosure provides a method for preparing a hydrogel composition with thermos-sensitive and ionic reversible properties and the hydrogel composition prepared by the method. Related application products of the hydrogel composition of the present disclosure include wound dressings, drug carriers, three-dimensional cellular scaffolds, soluble microspheres, and cell capture and release systems, wherein the hydrogel composition with thermos-sensitive and ionic reversible properties has good in vitro and in vivo stability and high biocompatibility, and is non-toxic. The hydrogel composition can be removed and replaced by washing with metal chelating aqueous solution at low temperature.