公开(公告)号：US20150335248A1

公开(公告)日：2015-11-26

申请号：US14412053

申请日：2013-07-02

Applicant: National University of Singapore

Inventor： Zhiwei HUANG ,  Khek Yu HO ,  Mads Sylvest BERGHOLT ,  Wei ZHENG ,  Khay Guan YEOH ,  ShiyamlaB DURAIPANDIAN

IPC: A61B5/00 ,  G01N21/65 ,  A61B1/00

CPC classification number: A61B5/0075 ,  A61B1/00165 ,  A61B5/0084 ,  A61B2560/0233 ,  G01J2003/4424 ,  G01N21/274 ,  G01N21/65 ,  G01N2021/656 ,  G01N2201/08 ,  G01N2201/12753 ,  G01N2201/129

Abstract: A method of achieving instrument independent measurements for quantitative analysis of fiber-optic Raman spectroscope system, the system comprising a laser source, a spectroscope and a fiber optic probe to transmit light from the laser source to a target and return scattered light to the spectroscope, the method comprising transmitting light from the laser source to a standard target having a known spectrum, recording a calibration spectrum of the scattered light from the standard target, comparing the known spectrum and the calibration system and generating a probe and/or probe-system transfer function, and storing the transfer function. Further provided is a method of performing real-time diagnostic Raman spectroscopy optionally in combination with the other disclosed methods.

Abstract translation: 一种实现用于光纤拉曼光谱系统的定量分析的仪器独立测量的方法，该系统包括激光源，分光镜和光纤探针，以将来自激光源的光透射到目标物并将散射光返回到分光器， 所述方法包括将来自激光源的光传输到具有已知光谱的标准靶，记录来自标准靶的散射光的校准光谱，比较已知光谱和校准系统并产生探针和/或探针系统转移 功能，并存储传输功能。 进一步提供了可选地与其他公开的方法组合执行实时诊断拉曼光谱的方法。