公开(公告)号：US20180113237A1

公开(公告)日：2018-04-26

申请号：US15792807

申请日：2017-10-25

Applicant: Novartis AG

Inventor： Frank Chang ,  Feng Jing ,  Fei Cheng ,  Ying Zheng

IPC: G02B1/04 ,  C08G77/20 ,  C08G77/28 ,  C08L83/08 ,  C08J3/075 ,  C08L25/06 ,  C08L33/10

CPC classification number: G02B1/043 ,  B29D11/00038 ,  B29D11/00134 ,  C08F283/122 ,  C08F285/00 ,  C08F290/142 ,  C08F299/08 ,  C08G77/20 ,  C08G77/28 ,  C08G2210/00 ,  C08J3/075 ,  C08J3/247 ,  C08J2383/08 ,  C08L25/06 ,  C08L33/10 ,  C08L83/08 ,  C08L2205/02 ,  C08L83/04 ,  C08F2222/108 ,  C08F2220/286 ,  C08F226/10

Abstract: The invention provides a class of amphiphilic branched polydiorganosiloxane macromers and the uses thereof. Such a macromer comprises a polydiorganosiloxane polymer chain and two terminal groups free of any ethylenically unsaturated group, wherein the polydiorganosiloxane polymer chain comprises (1) at least 5 dimethylsiloxane units in a consecutive sequence, (2) at least two first siloxane units each having methyl as one of the two substituents of each first siloxane unit and one first first organic radical having one sole (meth)acryloyl group as the other substituent, (3) at least one second siloxane unit having methyl as one of the two substituents of the second siloxane unit and one second organic radical, which is free of any ethylenically unsaturated group and comprises one or more hydrophilic groups or polymer chains, as the other substituent.

公开(公告)号：US20180354214A1

公开(公告)日：2018-12-13

申请号：US16000928

申请日：2018-06-06

Applicant: Novartis AG

Inventor： Daqing Wu ,  Steve Yun Zhang ,  Xinming Qian ,  Zach Munoz ,  Frank Chang ,  Wei Liang ,  Ying Zheng ,  Richard Charles Breitkopf ,  Matthew D. Nelson ,  Augustine Twum Kumi

IPC: B29D11/00 ,  G02B1/04

CPC classification number: B29D11/00134 ,  B29D11/00067 ,  B29D11/00076 ,  C08G77/442 ,  C08L83/04 ,  G02B1/043

Abstract: The present invention generally relates to a method for producing inherently wettable silicone hydrogel contact lenses with a robusteness of lens shape and having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus.

公开(公告)号：US10527757B2

公开(公告)日：2020-01-07

申请号：US15792807

申请日：2017-10-25

Applicant: Novartis AG

Inventor： Frank Chang ,  Feng Jing ,  Fei Cheng ,  Ying Zheng

IPC: G02B1/04 ,  C08G77/20 ,  C08G77/28 ,  C08J3/075 ,  C08L25/06 ,  C08L33/10 ,  C08L83/08 ,  B29D11/00 ,  C08F283/12 ,  C08F290/06 ,  C08F299/08 ,  C08J3/24

Abstract: The invention provides a class of amphiphilic branched polydiorganosiloxane macromers and the uses thereof. Such a macromer comprises a polydiorganosiloxane polymer chain and two terminal groups free of any ethylenically unsaturated group, wherein the polydiorganosiloxane polymer chain comprises (1) at least 5 dimethylsiloxane units in a consecutive sequence, (2) at least two first siloxane units each having methyl as one of the two substituents of each first siloxane unit and one first organic radical having one sole (meth)acryloyl group as the other substituent, (3) at least one second siloxane unit having methyl as one of the two substituents of the second siloxane unit and one second organic radical, which is free of any ethylenically unsaturated group and comprises one or more hydrophilic groups or polymer chains, as the other substituent.

公开(公告)号：US20180356562A1

公开(公告)日：2018-12-13

申请号：US16000930

申请日：2018-06-06

Applicant: Novartis AG

Inventor： Daqing Wu ,  Junhao Ge ,  Steve Yun Zhang ,  Richard Charles Breitkopf ,  Xinming Qian ,  Zach Munoz ,  Matthew D. Nelson ,  Augustine Twum Kumi ,  Weihong Lang ,  Ying Zheng ,  Feng Jing ,  Frank Chang

IPC: G02B1/04 ,  C08L83/04

CPC classification number: G02B1/043 ,  B29D11/00134 ,  C08F230/08 ,  C08L83/04

Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.

公开(公告)号：US20180355112A1

公开(公告)日：2018-12-13

申请号：US16000933

申请日：2018-06-06

Applicant: Novartis AG

Inventor： Steve Yun Zhang ,  Daqing Wu ,  Junhao Ge ,  Richard Charles Breitkopf ,  Xinming Qian ,  Zach Munoz ,  Matthew D. Nelson ,  Augustine Twum Kumi ,  Weihong Lang ,  Ying Zheng ,  Feng Jing ,  Frank Chang

IPC: C08G77/442 ,  C08G77/20 ,  C08G77/388 ,  C08G77/392 ,  C08G77/14 ,  C08G77/12 ,  C08L83/10 ,  G02B1/04

CPC classification number: C08G77/442 ,  B29D11/00134 ,  C08G77/12 ,  C08G77/14 ,  C08G77/20 ,  C08G77/388 ,  C08G77/392 ,  C08G2210/00 ,  C08L83/10 ,  C08L2201/10 ,  G02B1/043 ,  G02B2207/109 ,  G02C7/04

Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.