公开(公告)号：US20190179055A1

公开(公告)日：2019-06-13

申请号：US16204641

申请日：2018-11-29

Applicant: Novartis AG

Inventor： Yongxing Qiu ,  John Dallas Pruitt ,  Newton T. Samuel ,  Chung-Yuan Chiang ,  Robert Carey Tucker ,  Yuan Chang ,  Ethan Leveillee

IPC: G02B1/04 ,  C08L83/04 ,  C08L33/02 ,  C09D133/02 ,  C08L79/04

Abstract: The invention is related to contact lenses that not only comprise the much desired water gradient structural configurations, but also have a minimized uptakes of polycationic antimicrobials and a long-lasting surface hydrophilicity and wettability even after going through a 30-days lens care regime. Because of the water gradient structural configuration and a relatively-thick, extremely-soft and water-rich hydrogel surface layer, a contact lens of the invention can provide superior wearing comfort. Further, a contact lens of the invention is compatible with multipurpose lens care solutions present in the market and can endure the harsh lens care handling conditions (e.g., digital rubbings, accidental inversion of contact lenses, etc.) encountered in a daily lens care regime. As such, they are suitable to be used as weekly- or monthly-disposable water gradient contact lenses.

公开(公告)号：US11256003B2

公开(公告)日：2022-02-22

申请号：US16204641

申请日：2018-11-29

Applicant: Novartis AG

Inventor： Yongxing Qiu ,  John Dallas Pruitt ,  Newton T. Samuel ,  Chung-Yuan Chiang ,  Robert Carey Tucker ,  Yuan Chang ,  Ethan Leveillee

IPC: G02B1/04 ,  C08L33/02 ,  C08L79/04 ,  C09D133/02 ,  B29D11/00 ,  G02C7/04 ,  G02B1/18 ,  C08L83/04 ,  B05D5/00 ,  B65B55/22 ,  B05D3/00 ,  B05D5/10 ,  B05D1/38 ,  B05D3/02 ,  B05D1/18 ,  B29K83/00 ,  B29K105/00

Abstract: The invention is related to contact lenses that not only comprise the much desired water gradient structural configurations, but also have a minimized uptakes of polycationic antimicrobials and a long-lasting surface hydrophilicity and wettability even after going through a 30-days lens care regime. Because of the water gradient structural configuration and a relatively-thick, extremely-soft and water-rich hydrogel surface layer, a contact lens of the invention can provide superior wearing comfort. Further, a contact lens of the invention is compatible with multipurpose lens care solutions present in the market and can endure the harsh lens care handling conditions (e.g., digital rubbings, accidental inversion of contact lenses, etc.) encountered in a daily lens care regime. As such, they are suitable to be used as weekly- or monthly-disposable water gradient contact lenses.