公开(公告)号：US20240042713A1

公开(公告)日：2024-02-08

申请号：US18273145

申请日：2022-12-06

Applicant: OCULAR THERAPEUTIX, INC.

Inventor： Peter JARRETT ,  Rami EL-HAYEK ,  Erica KAHN ,  Dinesh HASWANI ,  Eric DICKINSON ,  Timothy S. JARRETT ,  Michael MCGRATH

IPC: B29D11/00 ,  A61K31/573 ,  A61K9/00

CPC classification number: B29D11/0074 ,  A61K31/573 ,  A61K9/0051 ,  B29K2071/02

Abstract: The present invention is directed to a method of preparing a sustained release biodegradable ocular insert or implant comprising melt extruding or injection molding a polymer composition and an active agent to form an insert or implant suitable for administration to the body. e.g., ocular administration. The method comprises feeding the polymer composition and the active into an extruder; mixing the components in the extruder; extruding a strand; and cutting the strand into unit dose inserts or implants.

公开(公告)号：US20240041647A1

公开(公告)日：2024-02-08

申请号：US18282124

申请日：2022-03-24

Applicant: OCULAR THERAPEUTIX, INC.

Inventor： Peter JARRETT ,  Erik WONG ,  Eric DICKINSON

IPC: A61F9/00

CPC classification number: A61F9/0017

Abstract: A system (100) includes a first assembly (110A) and a second assembly (110B). The first assembly (110A) includes a body (120) forming a first interior volume, a plunger (130) comprising a first distal end disposed within the first interior volume, a wire comprising a first distal end secured to the first distal end of the plunger (130), and a plunger clip (140) configured to interface with the plunger (130) and the body (120) to prevent actuation of the plunger (130). The second assembly (110B) includes a cowl (150) forming a second interior volume, a needle comprising a hub and a shaft, and a cowl cap disposed partially within the hub to secure the implant in the shaft. A first distal end of the shaft is connected to the hub. The hub is disposed within the second interior volume. The shaft is configured to receive an implant.