公开(公告)号：US20240042713A1

公开(公告)日：2024-02-08

申请号：US18273145

申请日：2022-12-06

Applicant: OCULAR THERAPEUTIX, INC.

Inventor： Peter JARRETT ,  Rami EL-HAYEK ,  Erica KAHN ,  Dinesh HASWANI ,  Eric DICKINSON ,  Timothy S. JARRETT ,  Michael MCGRATH

IPC: B29D11/00 ,  A61K31/573 ,  A61K9/00

CPC classification number: B29D11/0074 ,  A61K31/573 ,  A61K9/0051 ,  B29K2071/02

Abstract: The present invention is directed to a method of preparing a sustained release biodegradable ocular insert or implant comprising melt extruding or injection molding a polymer composition and an active agent to form an insert or implant suitable for administration to the body. e.g., ocular administration. The method comprises feeding the polymer composition and the active into an extruder; mixing the components in the extruder; extruding a strand; and cutting the strand into unit dose inserts or implants.