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公开(公告)号：US12173034B2
公开(公告)日：2024-12-24
申请号：US16766596
申请日：2018-11-22
Applicant: OSAKA UNIVERSITY
Inventor： Yukako Fujinaga , Sho Amatsu , Masahiro Kinooka
Abstract: The present invention provides a miniaturized hemagglutinin complex protein having function inhibitory activity against E-cadherin, wherein (a) all or a part of at least HA1 subcomponent, and/or a part of HA3 subcomponent are/is deleted, (b) regions in HA2 and HA3 subcomponents that contribute to binding with E-cadherin are present, and (c) the HA3 subcomponent is derived from Clostridium botulinum type A or type B, and an E-cadherin function inhibitor containing the hemagglutinin complex protein.
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