公开(公告)号：US11634656B2

公开(公告)日：2023-04-25

申请号：US16919477

申请日：2020-07-02

Applicant: OrbusNeich Medical PTE. LTD.

Inventor： Jingjing Zhu ,  Songyun Xu ,  Mian Li ,  Chang Peng ,  Yirong Gong

IPC: C10M169/04 ,  A61L29/08 ,  A61L29/14 ,  B05D3/06 ,  B05D3/10 ,  C10M107/32 ,  C10M107/34 ,  C10M107/42 ,  C10M155/02 ,  C10N40/00 ,  C10N50/00

Abstract: The invention discloses a photocured medical catheter hydrophilic lubricating coating and a preparation method thereof. The hydrophilic lubricating coating comprises a primer coating and a lubricating coating. The primer coating is attached to the surface of a device, and the lubricating coating is attached to the primer coating. The primer coating comprises 1-10 parts by weight of one or more polyester acrylates, 50-90 parts by weight of one or more solvents, 0.5-5 parts by weight of one or more photoinitiators, 0.5-2 parts by weight of one or more wetting agents and 0.5-5 parts by weight of one or more reactive (or active) diluents. The lubricating coating comprises 1-10 parts by weight of one or more water soluble macromolecules, 1-5 parts by weight of one or more crosslinking (or crosslinked) macromolecules, 0-1 part by weight of one or more photoinitiators, 0.1-1 part by weight of one or more surfactants and 50-98 parts by weight of one or more solvents. The preparation method of the hydrophilic lubricating coating is simple and easy in operation. Substance residues caused by complicated high-temperature chemical reactions are avoided. The cured coating forms a crosslinking (or crosslinked) structure, has good adhesion on the surface of a medical catheter and has excellent and lasting lubricity in an aqueous medium. The friction coefficient of the surface of the medical catheter is reduced. Harm to human tissues and adhesion of macromolecules in blood are decreased.