公开(公告)号：US20130327657A1

公开(公告)日：2013-12-12

申请号：US13905841

申请日：2013-05-30

Applicant: PANASONIC CORPORATION

Inventor： Makoto TAKAHASHI ,  Satoshi ARIMOTO

IPC: G01N27/416

CPC classification number: G01N27/416 ,  G01N27/3274

Abstract: Provided is a method for accurately quantifying a chemical substance contained in a sample solution at a significantly low concentration of not more than 1×10−8M. First, prepared is a measurement system including a counter electrode 13, a first reference electrode 12, a first working electrode 11a, a second working electrode 11b and a second reference electrode 14. Second, voltages of V1 volts and V2 volts (V1>V2) are applied to the first working electrode 11a and the second working electrode 11b, respectively. Third, a voltage difference ΔE between the second working electrode 11b and the second reference electrode 14 is measured. Finally, the concentration of the chemical substance is calculated on the basis of the voltage difference ΔE.

Abstract translation: 提供了以不大于1×10-8M的显着低浓度精确地定量样品溶液中所含的化学物质的方法。 首先，准备了包括对电极13，第一参考电极12，第一工作电极11a，第二工作电极11b和第二参考电极14的测量系统。其次，V1伏特和V2伏特的电压（V1> V2 ）分别施加到第一工作电极11a和第二工作电极11b。 第三，测量第二工作电极11b和第二参考电极14之间的电压差ΔE。 最后，根据电压差DeltaE计算化学物质的浓度。

公开(公告)号：US20130102099A1

公开(公告)日：2013-04-25

申请号：US13713065

申请日：2012-12-13

Applicant: PANASONIC CORPORATION

Inventor： Makoto TAKAHASHI ,  Masaya NAKATANI ,  Hiroshi USHIO ,  Takeki YAMAMOTO

IPC: H01L21/02

CPC classification number: H01L21/02356 ,  G01N33/48728

Abstract: A cellular electrophysiology sensor is adapted to measure an electrical change of a test cell. A chip for the sensor includes a diaphragm, and a thermally-oxidized film mainly containing silicon dioxide on the diaphragm. The diaphragm includes a silicon layer and a silicon dioxide layer on an upper surface of the silicon layer. A through-hole passing through the silicon layer and the silicon dioxide layer is formed. The through-hole has an opening which opens at the silicon dioxide layer and is adapted to capture the test cell. The thermally-oxidized film is provided on an inner wall surface of the through-hole, and unified with the silicon dioxide layer at the opening of the through-hole. This cellular electrophysiology sensor chip can stably capture the test cell and provides a gigaseal stably even if test cells have different properties.

Abstract translation: 细胞电生理学传感器适于测量测试电池的电气变化。 用于传感器的芯片包括隔膜以及在隔膜上主要含有二氧化硅的热氧化膜。 隔膜在硅层的上表面上包括硅层和二氧化硅层。 形成穿过硅层和二氧化硅层的通孔。 通孔具有在二氧化硅层处开口并且适于捕获测试电池的开口。 热氧化膜设置在通孔的内壁表面上，并且在通孔的开口处与二氧化硅层一体化。 这种细胞电生理学传感器芯片可以稳定地捕获测试细胞，并且即使测试细胞具有不同的性质也能稳定地提供gigaseal。

公开(公告)号：US20130040094A1

公开(公告)日：2013-02-14

申请号：US13651103

申请日：2012-10-12

Applicant: PANASONIC CORPORATION

Inventor： Masaya NAKATANI ,  Hiroshi USHIO ,  Soichiro HIRAOKA ,  Akiyoshi OSHIMA ,  Makoto TAKAHASHI

IPC: B32B5/02

CPC classification number: G01N33/48728 ,  B81B2201/0214 ,  B81B2201/052 ,  B81C1/00206 ,  Y10T428/23943

Abstract: A silicon structure of the present invention is provided with a silicon substrate (1) to become a base, and a plurality of fibrous projections (2) made of silicon dioxide and directly joined to a silicon-made surface (1a) of the silicon substrate (1). By arbitrarily constructing an area where these fibrous projections (2) are formed in a predetermined area, it is possible to render the area to have at least either hydrophilicity or water retentivity, so as to provide a silicon structure useful for a variety of devices.

Abstract translation: 本发明的硅结构设置有成为基底的硅基板（1）和由二氧化硅制成的直接接合到硅基板的硅制表面（1a）的多个纤维突起（2） （1）。 通过任意构造这些纤维状突起（2）形成在预定区域的区域，可以使该区域具有至少亲水性或保水性，以提供可用于各种装置的硅结构。

公开(公告)号：US20130288350A1

公开(公告)日：2013-10-31

申请号：US13928888

申请日：2013-06-27

Applicant: Panasonic Corporation

Inventor： Masaya NAKATANI ,  Makoto TAKAHASHI ,  Hiroshi USHIO ,  Daniel YAZBECK

IPC: C12Q1/68

CPC classification number: C12Q1/6876 ,  B01J19/0046 ,  B01J2219/00432 ,  B01J2219/00509 ,  B01J2219/00529 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00608 ,  B01J2219/00612 ,  B01J2219/00635 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00722 ,  C12Q1/6825 ,  C12Q1/6837 ,  C12Q1/6874 ,  C12Q2565/507

Abstract: A sequencer that measures a nucleic acid sequence in a nucleic acid strand includes: a base material having a surface made of silicon, and a fibrous protrusion that is made of silicon dioxide and is directly joined to the surface of the base material made of silicon, wherein a plurality of the nucleic acid strands are fixed onto the fibrous protrusion.

Abstract translation: 测量核酸链中的核酸序列的测序仪包括：具有由硅制成的表面的基材和由二氧化硅制成并直接接合到由硅制成的基材的表面的纤维状突起， 其中多个核酸丝束固定在纤维突起上。