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公开(公告)号：US20240156342A1
公开(公告)日：2024-05-16
申请号：US18372439
申请日：2023-09-25
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventor： Robert Vince , Swati Sudhakar More
IPC: A61B3/12 , A61B3/14 , A61B5/00 , A61K38/06 , G01J3/00 , G01J3/28 , G01J3/40 , G01N21/25 , G01N21/31 , G01N33/50
CPC classification number: A61B3/12 , A61B3/14 , A61B5/4848 , A61K38/063 , G01J3/00 , G01J3/28 , G01J3/40 , G01N21/25 , G01N21/31 , G01N33/5038
Abstract: Described herein is the use of a visible near infrared (VNIR) hyperspectral imaging system as a non-invasive diagnostic tool for early detection of Alzheimer's disease (AD). Also described herein is the use of a VNIR hyperspectral imaging system in high throughput screening of potential therapeutics against AD.
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公开(公告)号：US11642023B2
公开(公告)日：2023-05-09
申请号：US17365483
申请日：2021-07-01
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventor： Robert Vince , Swati Sudhakar More
IPC: G01J3/28 , A61B3/12 , G01N21/31 , G01J3/00 , G01J3/40 , G01N21/25 , A61B3/14 , A61K38/06 , G01N33/50 , A61B5/00
CPC classification number: A61B3/12 , A61B3/14 , A61B5/4848 , A61K38/063 , G01J3/00 , G01J3/28 , G01J3/40 , G01N21/25 , G01N21/31 , G01N33/5038
Abstract: Described herein is the use of a visible near infrared (VNIR) hyperspectral imaging system as a non-invasive diagnostic tool for early detection of Alzheimer's disease (AD). Also described herein is the use of a VNIR hyperspectral imaging system in high throughput screening of potential therapeutics against AD.
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公开(公告)号：US09987211B2
公开(公告)日：2018-06-05
申请号：US14901979
申请日：2014-07-02
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventor： Robert Vince , Abbas Raza , Christine Dreis
IPC: A61K8/49 , A61K8/58 , C07D239/54 , A61K8/04 , C07F7/08 , A61K8/11 , A61K8/02 , A61Q19/04 , C07D487/16 , C07D403/12 , C07D403/06 , C07D239/52
CPC classification number: A61K8/4953 , A61K8/0204 , A61K8/046 , A61K8/11 , A61K8/585 , A61K2800/91 , A61Q19/04 , C07D239/52 , C07D239/54 , C07D403/06 , C07D403/12 , C07D487/16 , C07F7/0889
Abstract: The invention provides sunless tanning compositions comprising a compounds of formula (I): or a salt thereof as described herein as well as methods for tanning mammalian skin by contacting the skin with the compounds of formula (I) or compositions comprising compounds of formula (I).
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公开(公告)号：US20140350036A1
公开(公告)日：2014-11-27
申请号：US14371900
申请日：2013-01-11
Applicant: Regents of the University of Minnesota
Inventor： Robert Vince , Abbas Raza , Christine Dreis
IPC: C07D239/22 , C07D487/16 , C07D487/04
CPC classification number: C07D239/22 , A61K8/4953 , A61K31/506 , A61K31/513 , A61K31/519 , A61K31/695 , A61K45/06 , A61Q17/04 , A61Q19/004 , C07D403/12 , C07D487/04 , C07D487/16 , A61K2300/00
Abstract: The invention provides compounds of formula I: or a salt thereof as described herein. The invention also provides dermatological compositions comprising a compound of formula I or mixtures of one or more compounds of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for protecting skin or DNA from photodamage or repairing photodamaged skin or DNA.
Abstract translation: 本发明提供了本文所述的式I化合物或其盐。 本发明还提供包含式I化合物或一种或多种式I化合物的混合物的皮肤病学组合物，制备式I化合物的方法，可用于制备式I化合物的中间体和用于保护皮肤或DNA免受光损伤的治疗方法或 修复光损伤的皮肤或DNA。
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公开(公告)号：US20250093204A1
公开(公告)日：2025-03-20
申请号：US18778628
申请日：2024-07-19
Applicant: Regents of the University of Minnesota
Inventor： Robert Vince , Swati Sudhakar More , James Melvin Beach
Abstract: In general, an imaging system to synchronously record a spatial image and a spectral image of a portion of the spatial image is described. In some examples, a beam splitter of the imaging system splits an optical beam, obtained from a viewing device, into a first split beam directed by the imaging system to a spatial camera and a second split beam directed by the imaging system to the entrance slit of an imaging spectrograph that is coupled to a spectral camera. An electronic apparatus synchronously triggers the spatial camera and the spectral camera to synchronously record a spatial image and a spectral image, respectively.
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Patent Agency Ranking
公开(公告)号：US11479579B2
公开(公告)日：2022-10-25
申请号：US17256421
申请日：2019-07-01
Applicant: Regents of the University of Minnesota
Inventor： Robert Vince , Swati Sudhakar More , Abbas Raza
Abstract: Disclosed herein are compounds of formula I: (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, and R3 may any of the values defined herein, as well as compositions comprising such compounds. Also disclosed are methods for treating diseases including neurodegenerative disorders such as Parkinson's Disease and Alzheimer's Disease.
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公开(公告)号：US20190330157A1
公开(公告)日：2019-10-31
申请号：US16429507
申请日：2019-06-03
Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventor： Swati S. More , Robert Vince
IPC: C07D233/44 , A61P25/16 , C07C279/08 , A61P35/00 , A61P5/48 , C07C279/06 , C07D239/47 , C07D239/22 , C07C335/12 , C07D213/61 , C07C335/40 , C07C335/04 , C07D239/18 , C07D239/06 , C07D233/64 , C07D233/52 , C07D233/50 , C07D231/38 , C07C281/18 , C07C281/16 , C07C281/14 , C07C279/22 , C07C279/18
Abstract: The invention provides methods for producing analgesia in an animal comprising administering to the animal a compound of the formula Ia′, Ib′, Ic′, and Id′: and pharmaceutically acceptable salts thereof, wherein the variables A, R6, R7, R8, R9, Rx, L, X, Y, and Z have the meaning as described herein.
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公开(公告)号：US09403778B2
公开(公告)日：2016-08-02
申请号：US14371900
申请日：2013-01-11
Applicant: Regents of the University of Minnesota
Inventor： Robert Vince , Abbas Raza , Christine Dreis
IPC: C07D239/22 , C07D487/04 , C07D487/16 , C07D403/12 , A61K45/06 , A61K31/506 , A61K31/513 , A61K31/519 , A61K31/695 , A61K8/49 , A61Q17/04 , A61Q19/00
CPC classification number: C07D239/22 , A61K8/4953 , A61K31/506 , A61K31/513 , A61K31/519 , A61K31/695 , A61K45/06 , A61Q17/04 , A61Q19/004 , C07D403/12 , C07D487/04 , C07D487/16 , A61K2300/00
Abstract: The invention provides compounds of formula I: or a salt thereof as described herein. The invention also provides dermatological compositions comprising a compound of formula I or mixtures of one or more compounds of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods for protecting skin or DNA from photodamage or repairing photodamaged skin or DNA.
Abstract translation: 本发明提供了本文所述的式I化合物或其盐。 本发明还提供包含式I化合物或一种或多种式I化合物的混合物的皮肤病学组合物，制备式I化合物的方法，可用于制备式I化合物的中间体和用于保护皮肤或DNA免受光损伤的治疗方法或 修复光损伤的皮肤或DNA。
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公开(公告)号：US20250017909A1
公开(公告)日：2025-01-16
申请号：US18441087
申请日：2024-02-14
Applicant: Regents of the University of Minnesota
Inventor： Robert Vince , Swati Sudhakar More
IPC: A61K31/426 , A61K31/198 , A61K31/22 , A61K31/265 , A61K31/385 , A61K31/554 , A61P25/28
Abstract: The invention provides compositions and methods for treating conditions associated with decreased activity of hydrogen sulfide.
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公开(公告)号：US20220148170A1
公开(公告)日：2022-05-12
申请号：US17455031
申请日：2021-11-16
Applicant: Regents of the University of Minnesota
Inventor： Robert Vince , Swati Sudhakar More , James Melvin Beach
Abstract: In general, an imaging system to synchronously record a spatial image and a spectral image of a portion of the spatial image is described. In some examples, a beam splitter of the imaging system splits an optical beam, obtained from a viewing device, into a first split beam directed by the imaging system to a spatial camera and a second split beam directed by the imaging system to the entrance slit of an imaging spectrograph that is coupled to a spectral camera. An electronic apparatus synchronously triggers the spatial camera and the spectral camera to synchronously record a spatial image and a spectral image, respectively.
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