公开(公告)号：US20240158660A1

公开(公告)日：2024-05-16

申请号：US18284359

申请日：2022-03-23

Applicant: TOSOH CORPORATION

Inventor： Yusuke NEZU ,  Shinya IMATOMI ,  Shimou CHINSON ,  Hiroyuki ITO

IPC: C09D125/08 ,  C09D133/02

CPC classification number: C09D125/08 ,  C09D133/02

Abstract: It is possible to provide a surface treatment agent containing a cell-adhesive polymer, by a surface treatment agent obtained by dissolving a water-insoluble polymer compound including constituents of (A) a monomer having a functional group exhibiting acidity and (B) a monomer having a HLB value (a Griffin's method) in a range of 0 to 5.0, in which a ratio of (A) is 10 to 50 mol %, and a solvent is an alcoholic solvent.

公开(公告)号：US20240158730A1

公开(公告)日：2024-05-16

申请号：US18284133

申请日：2022-03-23

Applicant: TOSOH CORPORATION

Inventor： Yumiko JIDO ,  Shoya HIRATOKO ,  Shinya IMATOMI ,  Hiroyuki ITO

IPC: C12M1/12 ,  C08J5/18 ,  C08L53/00

CPC classification number: C12M25/02 ,  C08J5/18 ,  C08L53/00 ,  C08L2203/02 ,  C08L2203/16

Abstract: Provided are a temperature-responsive polymer surface treatment agent containing: a temperature-responsive polymer; and a cell-adhesive polymer including a monomer having a functional group exhibiting acidity and a monomer having a HLB value (a Griffin's method) in a range of 0 to 5.0, and a temperature-responsive cell culture substrate obtained by covering a substrate with the temperature-responsive polymer surface treatment agent, in which cell adhesiveness and cell recovery by a cooling treatment are compatible.

公开(公告)号：US20190194376A1

公开(公告)日：2019-06-27

申请号：US16322361

申请日：2017-07-28

Applicant: TOSOH CORPORATION

Inventor： Yukie MAEJIMA ,  Satoru KONDOU ,  Shinya IMATOMI ,  Satoru YAMADA ,  Hiroyuki ITO

IPC: C08F299/02 ,  C12N5/00 ,  C08G81/02 ,  C08G61/02 ,  C08F20/56 ,  C08F20/18

CPC classification number: C08F299/024 ,  C08F20/18 ,  C08F20/56 ,  C08F293/00 ,  C08G61/025 ,  C08G81/02 ,  C08G81/024 ,  C08G2261/126 ,  C08G2261/1424 ,  C08G2261/143 ,  C08G2261/76 ,  C12M3/00 ,  C12N5/0068 ,  C12N2533/30

Abstract: The present invention addresses the problem of providing a block copolymer which is useful as a surface treatment agent for cell culture substrates, said surface treatment agent enabling cell separation in a short period of time. The above-mentioned problem is solved by a block copolymer that includes the following blocks (A), (B) and (C):(A) a temperature-responsive polymer block that has a lower critical solution temperature (LCST) within the range of from 0° C. to 50° C. with respect to water (B) a hydrophilic polymer block that does not have an LCST within the range of from 0° C. to 50° C., while having an HLB value within the range of from 9 (inclusive) to 20 (exclusive) (C) a hydrophobic polymer block that does not have an LCST within the range of from 0° C. to 50° C., while having an HLB value within the range of from 0 (inclusive) to 9 (exclusive).

公开(公告)号：US20160167026A1

公开(公告)日：2016-06-16

申请号：US14905517

申请日：2014-07-17

Applicant: TOSOH CORPORATION

Inventor： Tetsuo ASAKAWA ,  Sae SOMEYA ,  Tomokazu OHASHI ,  Shinya IMATOMI ,  Hideyuki HAMAJI ,  Yoshihiko MORI ,  Motohiro OGURI

IPC: B01J27/138 ,  B01J35/02 ,  C07C17/156

CPC classification number: B01J27/138 ,  B01J27/122 ,  B01J35/002 ,  B01J35/02 ,  B01J35/023 ,  B01J35/026 ,  B01J35/04 ,  B01J35/08 ,  B01J35/10 ,  B01J35/1061 ,  B01J35/108 ,  B01J35/1085 ,  B01J35/109 ,  B01J37/0207 ,  B01J2208/00513 ,  B01J2523/00 ,  C07C17/156 ,  C07C19/045 ,  B01J2523/13 ,  B01J2523/17 ,  B01J2523/31 ,  B01J2523/12 ,  B01J2523/15 ,  B01J2523/22 ,  B01J2523/41

Abstract: To provide a heterogeneous catalyst that exhibits high activity and high selectivity, specifically a catalyst suitable for oxychlorination to produce 1,2-dichloroethane from ethylene, and a catalyst system. Provided are: a heterogeneous catalyst supported on a porous carrier, characterized in that the integral value of the hysteresis occurring between an adsorption isotherm and a desorption isotherm by a gas adsorption method, is at most 19% to the total integral value of the adsorption isotherm; and a catalyst system for producing 1,2-dichloroethane, which comprises this catalyst and a diluent having a spherical shape, circular cylindrical shape or hollow cylindrical shape.

Abstract translation: 提供显示高活性和高选择性的非均相催化剂，特别是适用于氧氯化从乙烯生产1,2-二氯乙烷的催化剂和催化剂体系。 提供：负载在多孔载体上的多相催化剂，其特征在于通过气体吸附法吸附等温线和解吸附等温线之间的滞后积分值与吸附等温线的总积分值相差至多19％ ; 以及包含该催化剂的1,2-二氯乙烷的制造催化剂体系和具有球状，圆筒状或中空圆筒状的稀释剂。