公开(公告)号：US20150013439A1

公开(公告)日：2015-01-15

申请号：US14372438

申请日：2013-01-25

Applicant: The Regents of the University of California

Inventor： Cristina Davis ,  Hamzeh Bardaweel ,  Konstantin Zamuruyev ,  Jean-Pierre Delplanque ,  Nicholas J. Kenyon

IPC: A61B5/00 ,  A61B5/083 ,  G01N1/40 ,  A61B10/00

CPC classification number: G01N33/497 ,  A61B5/083 ,  A61B5/4845 ,  A61B10/0045 ,  G01N1/2202 ,  G01N1/4022 ,  G01N21/03 ,  G01N2001/002 ,  G01N2001/2282 ,  G01N2001/4033 ,  G01N2021/035

Abstract: A micro-analyzer is described. This micro-analyzer includes an outer surface region on a sampler surface that receives liquid droplets, and aggregates and moves the droplets radially toward an inner surface region on the sampler surface that receives the droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient. After the droplets are aggregated, an analysis mechanism in an area within the inner surface region performs analysis on the aggregated droplets.

Abstract translation: 描述微量分析仪。 该微量分析仪包括采样器表面上的接收液滴的外表面区域，并且聚集并将液滴径向移动到接收液滴的采样器表面上的内表面区域。 例如，外表面区域可以包括一组微图案化的同心环，每个环包括一组径向取向的壁 - 槽对。 此外，采样器表面可沿着朝向采样器表面的中心的径向方向越来越少的疏水性，从而产生轴对称的润湿性梯度。 在液滴聚集之后，内表面区域内的分析机构对聚集的液滴进行分析。

公开(公告)号：US09398881B2

公开(公告)日：2016-07-26

申请号：US14372438

申请日：2013-01-25

Applicant: The Regents of the University of California

Inventor： Cristina Davis ,  Hamzeh Bardaweel ,  Konstantin Zamuruyev ,  Jean-Pierre Delplanque ,  Nicholas J. Kenyon

IPC: G01N1/00 ,  G01N33/497 ,  A61B5/00 ,  G01N21/03 ,  A61B5/083 ,  A61B10/00 ,  G01N1/22 ,  G01N1/40

CPC classification number: G01N33/497 ,  A61B5/083 ,  A61B5/4845 ,  A61B10/0045 ,  G01N1/2202 ,  G01N1/4022 ,  G01N21/03 ,  G01N2001/002 ,  G01N2001/2282 ,  G01N2001/4033 ,  G01N2021/035

Abstract: A micro-analyzer is described. This micro-analyzer includes an outer surface region on a sampler surface that receives liquid droplets, and aggregates and moves the droplets radially toward an inner surface region on the sampler surface that receives the droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient. After the droplets are aggregated, an analysis mechanism in an area within the inner surface region performs analysis on the aggregated droplets.

Abstract translation: 描述微量分析仪。 该微量分析仪包括采样器表面上的接收液滴的外表面区域，并且聚集并且将液滴径向移动到接收液滴的采样器表面上的内表面区域。 例如，外表面区域可以包括一组微图案化的同心环，每个环包括一组径向取向的壁 - 槽对。 此外，采样器表面可沿着朝向采样器表面的中心的径向方向越来越少的疏水性，从而产生轴对称的润湿性梯度。 在液滴聚集之后，内表面区域内的分析机构对聚集的液滴进行分析。

公开(公告)号：US10111606B2

公开(公告)日：2018-10-30

申请号：US14372436

申请日：2013-01-25

Applicant: The Regents of the University of California

Inventor： Cristina Davis ,  Hamzeh Bardaweel ,  Konstantin Zamuruyev ,  Jean-Pierre Delplanque ,  Nicholas J. Kenyon

IPC: G01N1/00 ,  G01N33/497 ,  A61B5/02 ,  A61B5/097 ,  A61B5/08 ,  A61B10/00 ,  G01N1/22 ,  G01N1/40

Abstract: An integrated condenser is described. This integrated condenser includes an outer surface region on a sampler surface that facilitates condensing at least a component in a received gas-phase sample into liquid-phase droplets on the sampler surface, and aggregating and moving the condensed droplets radially toward an inner surface region on the sampler surface that receives the condensed droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient.

公开(公告)号：US10067119B2

公开(公告)日：2018-09-04

申请号：US15187204

申请日：2016-06-20

Applicant: The Regents of the University of California

Inventor： Cristina Davis ,  Hamzeh Bardaweel ,  Konstantin Zamuruyev ,  Jean-Pierre Delplanque ,  Nicholas J. Kenyon

IPC: G01N1/02 ,  G01N21/03 ,  G01N33/497 ,  G01N1/22 ,  A61B5/083 ,  A61B5/00 ,  A61B10/00 ,  G01N1/00 ,  G01N1/40

Abstract: A method for analyzing droplets is described. The droplets can be received on an outer surface region of a sampler surface disposed on a substrate, wherein the sampler surface is increasingly less hydrophobic along a radial direction toward the center of the sampler surface. Next, the droplets can be aggregated and moved toward the center of the sampler surface. The droplets can then be received at an inner surface region of the sampler surface. Next, the droplets can be analyzed using an analysis mechanism in an area in the inner surface region.

公开(公告)号：US20160290992A1

公开(公告)日：2016-10-06

申请号：US15187204

申请日：2016-06-20

Applicant: The Regents of the University of California

Inventor： Cristina Davis ,  Hamzeh Bardaweel ,  Konstantin Zamuruyev ,  Jean-Pierre Delplanque ,  Nicholas J. Kenyon

IPC: G01N33/497 ,  A61B5/00 ,  A61B5/083 ,  G01N1/40 ,  G01N1/22

CPC classification number: G01N33/497 ,  A61B5/083 ,  A61B5/4845 ,  A61B10/0045 ,  G01N1/2202 ,  G01N1/4022 ,  G01N21/03 ,  G01N2001/002 ,  G01N2001/2282 ,  G01N2001/4033 ,  G01N2021/035

Abstract: A method for analyzing droplets is described. The droplets can be received on an outer surface region of a sampler surface disposed on a substrate, wherein the sampler surface is increasingly less hydrophobic along a radial direction toward the center of the sampler surface. Next, the droplets can be aggregated and moved toward the center of the sampler surface. The droplets can then be received at an inner surface region of the sampler surface. Next, the droplets can be analyzed using an analysis mechanism in an area in the inner surface region.

Abstract translation: 描述了分析液滴的方法。 液滴可以被接收在设置在基板上的取样器表面的外表面区域上，其中采样器表面沿径向方向越来越少地朝向取样器表面的中心。 接下来，液滴可以聚集并移动到采样器表面的中心。 然后可以在采样器表面的内表面区域接收液滴。 接下来，可以使用在内表面区域中的区域中的分析机构来分析液滴。

公开(公告)号：US20140358023A1

公开(公告)日：2014-12-04

申请号：US14372436

申请日：2013-01-25

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Cristina Davis ,  Hamzeh Bardaweel ,  Konstantin Zamuruyev ,  Jean-Pierre Delplanque ,  Nicholas J. Kenyon

IPC: A61B5/097 ,  A61B10/00 ,  A61B5/08

CPC classification number: A61B5/097 ,  A61B5/082 ,  A61B10/0051 ,  G01N1/2202 ,  G01N33/497 ,  G01N2001/2282 ,  G01N2001/4033

Abstract: An integrated condenser is described. This integrated condenser includes an outer surface region on a sampler surface that facilitates condensing at least a component in a received gas-phase sample into liquid-phase droplets on the sampler surface, and aggregating and moving the condensed droplets radially toward an inner surface region on the sampler surface that receives the condensed droplets. For example, the outer surface region may include a set of micro-patterned concentric rings, each of which includes a set of radially oriented wall-groove pairs. Moreover, the sampler surface may be increasingly less hydrophobic along a radial direction toward the center of the sampler surface, thereby creating an axisymmetric wettability gradient.

Abstract translation: 描述了一个集成的冷凝器。 该集成冷凝器包括采样器表面上的外表面区域，其有助于将接收的气相样品中的至少一个组分冷凝在采样器表面上的液相液滴中，并且将冷凝的液滴聚集并径向移动到内表面区域上 接收冷凝液滴的采样器表面。 例如，外表面区域可以包括一组微图案化的同心环，每个环包括一组径向取向的壁 - 槽对。 此外，采样器表面可沿着朝向采样器表面的中心的径向方向越来越少的疏水性，从而产生轴对称的润湿性梯度。