公开(公告)号：US20170239419A1

公开(公告)日：2017-08-24

申请号：US15513771

申请日：2015-09-21

Applicant: UCB BIOPHARMA SPRL ,  BESPAK EUROPE LIMITED

Inventor： Martin John McLoughlin ,  Barry Alan Knight ,  Matt Ekman ,  Deborah Jane Norris

IPC: A61M5/20 ,  A61M5/31 ,  A61M5/315 ,  A61M5/32

CPC classification number: A61M5/2033 ,  A61M5/3137 ,  A61M5/31576 ,  A61M5/3202 ,  A61M5/3243 ,  A61M2005/3125 ,  A61M2205/0216 ,  A61M2205/0238

Abstract: Provided is a housing part for an auto-injector comprising a shell form body defining inner and outer shell surfaces and comprising a relatively hard or generally incompressible material; an over-coating formed of a relatively softer or more compressible material, the over-coating covering at least part of the outer shell surface of the shell form body; and at least one window defined in the shell form body, wherein the over-coating extends into the at least one window. Also provided is a housing comprising the housing part, and an auto-injector comprising the housing.

公开(公告)号：US11517676B2

公开(公告)日：2022-12-06

申请号：US16679661

申请日：2019-11-11

Applicant: Bespak Europe Limited ,  UCB Biopharma SPRL

Inventor： Martin John McLoughlin ,  Ian Darnell ,  Matt Ekman ,  Ian Anderson ,  Neil Bentley Cammish

IPC: A61M5/31 ,  A61M5/24 ,  A61M5/20

Abstract: An assembly for an autoinjector device, the assembly including a syringe support for supporting a syringe by limiting forward axial movement of the syringe relative to the syringe support, and a guard element attachable to the syringe support by an attachment so that the guard element is axially restrained both axially forwardly and axially rearwardly relative to the syringe support by the attachment. Forwardly directed axial loads received by the guard element are transmitted to the syringe support via the attachment.

公开(公告)号：US09867941B2

公开(公告)日：2018-01-16

申请号：US14437393

申请日：2013-10-21

Applicant: UCB Biopharma SPRL

Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Cameron Townley Charles ,  Dylan Sanders Garrett ,  Kevin Richard Lozeau

IPC: A61M5/20 ,  A61M5/00 ,  A61M5/31 ,  A61M5/315 ,  A61M5/32 ,  H05K1/02 ,  H05K1/18 ,  A61M5/24

CPC classification number: A61M5/20 ,  A61M5/002 ,  A61M5/3134 ,  A61M5/31505 ,  A61M5/31515 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/208 ,  A61M2005/2477 ,  A61M2205/13 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2205/583 ,  A61M2205/586 ,  A61M2205/8206 ,  H05K1/0298 ,  H05K1/189 ,  H05K2201/052 ,  H05K2201/10151 ,  H05K2201/2009

Abstract: Provided is a drive unit for an auto-injector having a drive unit housing arranged for docking receipt of a syringe or of a cassette unit comprising a syringe movable from a rest position, in which a needle tip of the syringe is within the drive unit housing to a use position, in which the needle tip protrudes from a needle delivery aperture; and a drive arrangement including one or more electrically powered sources of axial drive; a first drive transfer element for advancing the syringe to said use position; and a second drive transfer element for moving a plunger into the barrel of the syringe to eject liquid contents thereof. The drive unit housing is provided with a skin sensor arrangement having an array of plural skin sensor electrodes located about the needle delivery aperture.

公开(公告)号：US09789254B2

公开(公告)日：2017-10-17

申请号：US15113254

申请日：2015-01-22

Applicant: UCB BIOPHARMA SPRL

Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Brian David Barney

IPC: A61M5/24 ,  A61M5/20

CPC classification number: A61M5/20 ,  A61M5/24 ,  A61M2005/2418 ,  A61M2005/244 ,  A61M2005/2481 ,  A61M2205/52 ,  A61M2205/584 ,  A61M2205/6054

Abstract: Provided is a cassette unit suitable for use with an auto-injector having a drive unit. The cassette unit comprises a cassette unit housing defining a cassette unit housing cavity, which is in receipt of a syringe, a rearward entrance to said cavity and a forward needle projection aperture. The cassette unit also comprises in capping relationship with the rearward entrance of the cassette unit housing, a cassette unit end-cap, said cassette unit end-cap defining a drive rod-receiving opening for receipt of a drive rod for providing forward axial drive to said plunger; a biasing element defining a biasing relationship between the cassette unit end-cap and an end flange of the syringe barrel, thereby urging the syringe forwards in relation to the cassette unit end-cap; and a damping element defining a damping relationship between the cassette unit end-cap and the flange of the syringe, thereby acting to damp rearward movement of the syringe relative to the cassette unit end-cap.

公开(公告)号：US09764101B2

公开(公告)日：2017-09-19

申请号：US14418437

申请日：2013-07-29

Applicant: UCB Biopharma SPRL

Inventor： Martin John McLoughlin ,  Ilario Melzi ,  Stefan Verlaak

IPC: A61M5/32 ,  A61M5/50 ,  A61M5/00 ,  A61M5/31 ,  A61M5/20 ,  A61M5/315 ,  A61M5/24

CPC classification number: A61M5/5086 ,  A61M5/002 ,  A61M5/20 ,  A61M5/3134 ,  A61M5/31505 ,  A61M5/31515 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/3213 ,  A61M5/326 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2477 ,  A61M2005/3139 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2205/583 ,  A61M2205/586 ,  A61M2205/8206

Abstract: There is provided a cassette unit suitable for use with an auto-injector. The cassette unit comprises a cassette unit housing and a removable cap that in a capping position fits over and thereby, acts to close off, a needle projection aperture of the housing. The cassette unit housing has one or more first engagement features arranged for reversibly engaging one or more second engagement features of the removable cap for reversible lock engagement of the removable cap to the housing; and a shuttle lock control defining one or more blocking elements for selectively blocking movement of said first engagement features relative to said second engagement features. The shuttle lock control is axially movable relative to the cassette unit housing between a first ‘cassette unused’ position; a second ‘cassette unlocked’ position; and after replacement of the removable cap, a third ‘cassette used’ position, locating intermediate the first and second positions.

公开(公告)号：US20200069878A1

公开(公告)日：2020-03-05

申请号：US16679661

申请日：2019-11-11

Applicant: Bespak Europe Limited ,  UCB Biopharma SPRL

Inventor： Martin John McLoughlin ,  Ian Darnell ,  Matt Ekman ,  Ian Anderson ,  Neil Bentley Cammish

IPC: A61M5/31 ,  A61M5/20 ,  A61M5/24

Abstract: An assembly for an autoinjector device, the assembly including a syringe support for supporting a syringe by limiting forward axial movement of the syringe relative to the syringe support, and a guard element attachable to the syringe support by an attachment so that the guard element is axially restrained both axially forwardly and axially rearwardly relative to the syringe support by the attachment. Forwardly directed axial loads received by the guard element are transmitted to the syringe support via the attachment.

公开(公告)号：US09821123B2

公开(公告)日：2017-11-21

申请号：US15113278

申请日：2015-01-22

Applicant: UCB BIOPHARMA SPRL

Inventor： Martin John McLoughlin ,  Michael James David Heald

IPC: A61M5/32 ,  A61M5/20 ,  A61M5/31 ,  A61M5/315

CPC classification number: A61M5/3204 ,  A61M5/20 ,  A61M5/3134 ,  A61M5/31515 ,  A61M5/31583 ,  A61M5/3202 ,  A61M5/3213 ,  A61M2005/3143 ,  A61M2005/3215 ,  A61M2005/3252 ,  A61M2205/13 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/584 ,  A61M2205/586 ,  A61M2205/6054 ,  A61M2205/80 ,  A61M2205/8206

Abstract: Provided is a cassette unit suitable for use with an auto-injector having a drive unit. The cassette unit comprises a cassette unit housing defining a cassette unit housing cavity arranged for receipt of a syringe; a needle projection aperture; a needle cover defining a needle sheath for sheathing of a needle tip of the syringe; a removable cap that in a capping position fits over and thereby, acts such as to close off, the needle projection aperture, the removable cap defining a cap interior; provided to the removable cap, a cap insert; and provided to the cap insert, a connector defining one or more needle cover gripping elements for gripping the needle cover and the connector defines a central hub and the one or more needle gripper elements attach to the central hub and in spaced arrangement relative to each other. The connector locates within the removable cap such that the central hub of the connector is in spaced relationship with a forward end wall or surface of the cap interior and the needle cover gripping elements project away from the forward end cap wall or surface of the cap interior and towards the open end of the cap, and wherein the cap insert is shaped to allow for limited axial travel of the connector there within.

公开(公告)号：US20150258278A1

公开(公告)日：2015-09-17

申请号：US14418440

申请日：2013-07-29

Applicant: UCB Biopharma SPRL

Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Ilario Melzi ,  Stefan Verlaak ,  Tatiana Palombi

IPC: A61M5/20 ,  A61M5/315 ,  A61M5/32

CPC classification number: A61M5/2053 ,  A61M5/20 ,  A61M5/315 ,  A61M5/3202 ,  A61M5/3213 ,  A61M2005/2026 ,  A61M2005/2073

Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit comprises a cassette unit housing defining a cassette unit housing cavity, a rearward entrance to said cavity and a forward needle projection aperture. The housing cavity may receive a syringe comprising a barrel; a needle at a front end of the barrel; and a plunger that is axially movable within the barrel. The cassette unit also comprises in capping relationship with the rearward entrance of the cassette unit housing, a cassette unit end-cap, said cassette unit end-cap defining a drive rod-receiving opening for receipt of a drive rod for providing forward axial drive to said plunger; and a biasing element defining a biasing relationship between the cassette unit end-cap and an end flange of the syringe barrel, thereby urging the syringe forwards in relation to the cassette unit end cap.

Abstract translation: 提供了适用于具有电动驱动单元的自动注射器的盒单元。 盒单元包括限定盒单元容纳腔的盒单元壳体，到所述腔的后入口和正向针突出孔。 壳体腔可以接收包括筒的注射器; 在枪管的前端的针; 以及在筒体内可轴向移动的柱塞。 盒单元还包括与盒单元壳体的后入口的封盖关系，盒单元端盖，所述盒单元端盖限定用于接收用于提供向前轴向驱动的驱动杆接收开口的驱动杆接收开口 柱塞 以及偏置元件，其限定所述盒单元端盖与所述注射器筒的端部凸缘之间的偏置关系，从而相对于所述盒单元端盖向前推动所述注射器。

公开(公告)号：US20150165135A1

公开(公告)日：2015-06-18

申请号：US14418437

申请日：2013-07-29

Applicant: UCB BIOPHARMA SPRL

Inventor： Martin John McLoughlin ,  Ilario Melzi ,  Stefan Verlaak

IPC: A61M5/50 ,  A61M5/32 ,  A61M5/31

CPC classification number: A61M5/5086 ,  A61M5/002 ,  A61M5/20 ,  A61M5/3134 ,  A61M5/31505 ,  A61M5/31515 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/3213 ,  A61M5/326 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2477 ,  A61M2005/3139 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2205/583 ,  A61M2205/586 ,  A61M2205/8206

Abstract: There is provided a cassette unit suitable for use with an auto-injector. The cassette unit comprises a cassette unit housing and a removable cap that in a capping position fits over and thereby, acts to close off, a needle projection aperture of the housing. The cassette unit housing has one or more first engagement features arranged for reversibly engaging one or more second engagement features of the removable cap for reversible lock engagement of the removable cap to the housing; and a shuttle lock control defining one or more blocking elements for selectively blocking movement of said first engagement features relative to said second engagement features. The shuttle lock control is axially movable relative to the cassette unit housing between a first ‘cassette unused’ position; a second ‘cassette unlocked’ position; and after replacement of the removable cap, a third ‘cassette used’ position, locating intermediate the first and second positions.

Abstract translation: 提供了适用于自动注射器的盒式装置。 盒单元包括盒单元壳体和可拆卸盖，其在封盖位置中装配并由此用于封闭壳体的针突起孔。 盒单元壳体具有一个或多个第一接合特征，其布置成可逆地接合可移除盖的一个或多个第二接合特征，用于可拆卸盖与壳体的可逆锁定接合; 以及定位一个或多个阻挡元件的梭锁控制，用于选择性地阻止所述第一接合特征相对于所述第二接合特征的运动。 梭动锁控制可相对于盒单元壳体在第一“盒未使用”位置之间轴向移动; 第二个“磁带解锁”位置; 并且在更换可拆卸盖之后，具有位于第一和第二位置之间的第三个“盒式磁带使用”位置。

公开(公告)号：US09757524B2

公开(公告)日：2017-09-12

申请号：US14418438

申请日：2013-07-29

Applicant: UCB Biopharma SPRL

Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Ilario Melzi ,  Stefan Verlaak ,  Tatiana Palombi

IPC: A61M5/20 ,  A61M5/315 ,  A61M5/24

CPC classification number: A61M5/31513 ,  A61M5/20 ,  A61M5/24 ,  A61M2005/2006 ,  A61M2005/2437

Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit comprises a cassette unit housing defining a housing cavity, a rearward entrance to the cavity and a forward needle projection aperture. The housing cavity may receive a syringe. Axially movable within the barrel of the syringe for forward movement into contact with the syringe plunger, there is a plunger slaving part defining a circumferential wall arranged for frictional sliding relationship with the inner wall of the barrel, a rear drive-receiving face and a front plunger-contacting face. In capping relationship with the rearward entrance of the cassette unit housing there is an end-cap defining a drive rod-receiving opening for receipt of a drive rod for providing forward axial drive to the plunger slaving part. In a pre-use configuration, the plunger slaving part is shaped for releasable engagement with the end-cap.