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    Auto-injector
    2.
    发明授权
    Auto-injector 有权

    公开(公告)号：US09789254B2

    公开(公告)日：2017-10-17

    申请号：US15113254

    申请日：2015-01-22

    Applicant: UCB BIOPHARMA SPRL

    Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Brian David Barney

    IPC: A61M5/24 ,  A61M5/20

    CPC classification number: A61M5/20 ,  A61M5/24 ,  A61M2005/2418 ,  A61M2005/244 ,  A61M2005/2481 ,  A61M2205/52 ,  A61M2205/584 ,  A61M2205/6054

    Abstract: Provided is a cassette unit suitable for use with an auto-injector having a drive unit. The cassette unit comprises a cassette unit housing defining a cassette unit housing cavity, which is in receipt of a syringe, a rearward entrance to said cavity and a forward needle projection aperture. The cassette unit also comprises in capping relationship with the rearward entrance of the cassette unit housing, a cassette unit end-cap, said cassette unit end-cap defining a drive rod-receiving opening for receipt of a drive rod for providing forward axial drive to said plunger; a biasing element defining a biasing relationship between the cassette unit end-cap and an end flange of the syringe barrel, thereby urging the syringe forwards in relation to the cassette unit end-cap; and a damping element defining a damping relationship between the cassette unit end-cap and the flange of the syringe, thereby acting to damp rearward movement of the syringe relative to the cassette unit end-cap.

    AUTO-INJECTOR
    5.
    发明申请
    AUTO-INJECTOR 有权
    自动注射器

    公开(公告)号：US20150258278A1

    公开(公告)日：2015-09-17

    申请号：US14418440

    申请日：2013-07-29

    Applicant: UCB Biopharma SPRL

    Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Ilario Melzi ,  Stefan Verlaak ,  Tatiana Palombi

    IPC: A61M5/20 ,  A61M5/315 ,  A61M5/32

    CPC classification number: A61M5/2053 ,  A61M5/20 ,  A61M5/315 ,  A61M5/3202 ,  A61M5/3213 ,  A61M2005/2026 ,  A61M2005/2073

    Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit comprises a cassette unit housing defining a cassette unit housing cavity, a rearward entrance to said cavity and a forward needle projection aperture. The housing cavity may receive a syringe comprising a barrel; a needle at a front end of the barrel; and a plunger that is axially movable within the barrel. The cassette unit also comprises in capping relationship with the rearward entrance of the cassette unit housing, a cassette unit end-cap, said cassette unit end-cap defining a drive rod-receiving opening for receipt of a drive rod for providing forward axial drive to said plunger; and a biasing element defining a biasing relationship between the cassette unit end-cap and an end flange of the syringe barrel, thereby urging the syringe forwards in relation to the cassette unit end cap.

    Abstract translation: 提供了适用于具有电动驱动单元的自动注射器的盒单元。 盒单元包括限定盒单元容纳腔的盒单元壳体，到所述腔的后入口和正向针突出孔。 壳体腔可以接收包括筒的注射器; 在枪管的前端的针; 以及在筒体内可轴向移动的柱塞。 盒单元还包括与盒单元壳体的后入口的封盖关系，盒单元端盖，所述盒单元端盖限定用于接收用于提供向前轴向驱动的驱动杆接收开口的驱动杆接收开口 柱塞 以及偏置元件，其限定所述盒单元端盖与所述注射器筒的端部凸缘之间的偏置关系，从而相对于所述盒单元端盖向前推动所述注射器。

    Auto-injector
    6.
    发明授权
    Auto-injector 有权

    公开(公告)号：US09757524B2

    公开(公告)日：2017-09-12

    申请号：US14418438

    申请日：2013-07-29

    Applicant: UCB Biopharma SPRL

    Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Ilario Melzi ,  Stefan Verlaak ,  Tatiana Palombi

    IPC: A61M5/20 ,  A61M5/315 ,  A61M5/24

    CPC classification number: A61M5/31513 ,  A61M5/20 ,  A61M5/24 ,  A61M2005/2006 ,  A61M2005/2437

    Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit comprises a cassette unit housing defining a housing cavity, a rearward entrance to the cavity and a forward needle projection aperture. The housing cavity may receive a syringe. Axially movable within the barrel of the syringe for forward movement into contact with the syringe plunger, there is a plunger slaving part defining a circumferential wall arranged for frictional sliding relationship with the inner wall of the barrel, a rear drive-receiving face and a front plunger-contacting face. In capping relationship with the rearward entrance of the cassette unit housing there is an end-cap defining a drive rod-receiving opening for receipt of a drive rod for providing forward axial drive to the plunger slaving part. In a pre-use configuration, the plunger slaving part is shaped for releasable engagement with the end-cap.

    AUTO-INJECTOR
    8.
    发明申请
    AUTO-INJECTOR 有权
    自动注射器

    公开(公告)号：US20150182691A1

    公开(公告)日：2015-07-02

    申请号：US14418441

    申请日：2013-07-29

    Applicant: UCB Biopharma SPRL

    Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Ilario Melzi ,  Stefan Verlaak ,  Tatiana Palombi

    IPC: A61M5/145 ,  A61M5/158

    CPC classification number: A61M5/1456 ,  A61M5/002 ,  A61M5/158 ,  A61M5/20 ,  A61M5/3134 ,  A61M5/31505 ,  A61M5/31515 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2477 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/505 ,  A61M2205/583 ,  A61M2205/586 ,  A61M2205/8206

    Abstract: Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit comprises a cassette unit housing defining a cassette unit housing cavity and a needle projection aperture. The housing cavity may receive a syringe. Axially movable within the barrel of the syringe for forward movement into contact with the syringe plunger, there is a plunger slaving part defining a circumferential wall arranged for frictional sliding relationship with the inner wall of the barrel, a rear drive-receiving face and a front plunger-contacting face. The plunger slaving part is arranged such that when a drive load is applied to its rear drive-receiving face to bring the front plunger-contacting face into contact with the plunger the drive load is evenly transmitted. The circumferential wall is provided with slide restrictors that restrict frictional sliding movement thereof in relation to the inner wall of the barrel.

    Abstract translation: 提供了适用于具有电动驱动单元的自动注射器的盒单元。 盒单元包括限定盒单元容纳腔和针突起孔的盒单元壳体。 容纳腔可以接收注射器。 在注射器的筒体内可轴向移动以向前运动以与注射器柱塞接触，存在一个柱塞从动部件，其限定周向壁布置成与筒体的内壁摩擦滑动关系，后驱动接收面和前部 柱塞接触面。 柱塞从动部件布置成使得当驱动负载施加到其后驱动接收面以使前柱塞接触面与柱塞接触时，驱动负载被均匀地传递。 圆周壁上设有滑动限制器，其限制了相对于筒体的内壁的摩擦滑动运动。

    Auto-injector
    9.
    发明授权
    Auto-injector 有权

    公开(公告)号：US10342925B2

    公开(公告)日：2019-07-09

    申请号：US15113296

    申请日：2015-01-22

    Applicant: UCB BIOPHARMA SPRL

    Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Brian David Barney

    IPC: A61M5/20 ,  A61M5/24 ,  A61M5/32

    Abstract: Provided is a cassette unit suitable for use with an auto-injector having a drive unit. The cassette unit comprises a cassette unit housing defining a cassette unit housing cavity arranged for receipt of a syringe; a needle projection aperture; a needle cover defining a needle sheath for sheathing of a needle tip of the syringe; a removable cap that in a capping position fits over and thereby, acts such as to close off, the needle projection aperture, the removable cap defining a cap interior; provided to the removable cap, a cap insert; and provided to the cap insert, a connector defining one or more needle cover gripping elements for gripping the needle cover and the connector defines a central hub and the one or more needle gripper elements attach to the central hub and in spaced arrangement relative to each other, wherein the connector locates within the removable cap such that the central hub of the connector is in spaced relationship with a forward end wall or surface of the cap interior and the needle cover gripping elements project away from the forward end cap wall or surface of the cap interior and towards the open end of the cap, and wherein the removable cap is shaped to allow for limited axial travel of the cap insert there within.

    Injector
    10.
    发明授权
    Injector 有权

    公开(公告)号：US10099013B2

    公开(公告)日：2018-10-16

    申请号：US14911670

    申请日：2014-08-11

    Applicant: UCB BIOPHARMA SPRL

    Inventor： Martin John McLoughlin ,  Michael James David Heald ,  Barry Alan Knight ,  Dirushan Pillay

    IPC: A61M5/24 ,  A61M5/31 ,  A61M5/315 ,  A61M5/50 ,  A61M5/32

    Abstract: Provided is a manual drive unit for use with a cassette unit comprising a cassette unit housing containing there within a syringe comprising a barrel for containing a volume of a liquid drug formulation; a hollow needle at a front end of the barrel, the hollow needle defining a needle tip for dispensing of the liquid drug formulation; and a plunger that is axially movable within the barrel. The manual drive unit comprises a manual drive unit housing defining a docking cavity and a needle delivery aperture, wherein said docking cavity is arranged for docking receipt of the cassette unit at a docking position; and received by the manual drive unit housing and axially movable relative thereto, a manually operable drive transfer element for transferring axial drive to the plunger of the syringe for moving the plunger into the barrel of the syringe to eject at least part of the volume of liquid drug formulation.

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