公开(公告)号：US20250009783A1

公开(公告)日：2025-01-09

申请号：US18702339

申请日：2021-11-16

Applicant: UNIVERSITY OF MACAU

Inventor： Chunming WANG ,  Jiaxi CHEN ,  Daping XIE ,  Zhe ZHANG

IPC: A61K31/728 ,  C08B37/08

Abstract: The present invention relates to the cross-technical fields of medicine, material chemistry, glycobiology and the like, in particular to a sulfonated hyaluronic acid compound, a preparation method therefor and an application thereof. The structural formula of the sulfonated hyaluronic acid compound is shown as in formula (I), wherein R is alkali metal cation or hydrogen; R1, R2, R3 and R4 are respectively independently selected from hydrogen or sulfonate ions and R1, R2, R3 and R4 cannot be hydrogen at the same time, 10