公开(公告)号：US11560387B2

公开(公告)日：2023-01-24

申请号：US17468048

申请日：2021-09-07

Applicant: University of Windsor

Inventor： John Frederick Trant ,  Daniel Meister ,  Sarah Nasri ,  Anthony Emanuel Chifor ,  John James Hayward ,  Seyedeh Maryamdokht Taimoory ,  Mohadeseh Dashti-Pour

IPC: C07D491/18 ,  C07K1/06

Abstract: In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.

公开(公告)号：US20250084089A1

公开(公告)日：2025-03-13

申请号：US18821262

申请日：2024-08-30

Applicant: University of Windsor

Inventor： John F. Trant ,  Lisa A. Porter ,  Bre-Anne Fifield ,  Daniel Meister ,  John J. Hayward ,  Lavleen Mader ,  Maria Teodora Secara

IPC: C07D487/04 ,  A61K31/519 ,  G01N33/574

Abstract: In a preferred embodiment, there is provided a compound having structural Formula I, II, III or IV.