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公开(公告)号：US20230358739A1
公开(公告)日：2023-11-09
申请号：US17786440
申请日：2020-12-18
Applicant: Vidya Holdings Ltd
Inventor： Stefan Leo Van Workum , Vladimir Alexander Turek , Marko Dorrestijn , David R. Klug
IPC: G01N33/543 , B01L3/00
CPC classification number: G01N33/54386 , B01L3/5023 , B01L3/502753 , B01L2200/147 , B01L2200/16 , B01L2300/0681 , B01L2300/069 , B01L2300/0816 , B01L2300/123 , B01L2400/0481
Abstract: A sample management module for receiving a fluid sample for an immunoassay is provided. The module comprises: a sample reception device for receiving a sample; a detection reagent; a controller configured to initiate a reaction timer on the basis of an actuation event when the sample and detection reagent are brought into contact.
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公开(公告)号：US20220143608A1
公开(公告)日：2022-05-12
申请号：US17435373
申请日：2020-02-28
Applicant: Vidya Holdings Ltd
Inventor： Stefan Leo Van Workum , Callum Robertson Smith , Marko Dorrestijn , David R. Klug
Abstract: A sample management module for collecting a fluid sample is provided. The module comprising; a sample collection device comprising a sample collection location; a decoupling zone configured to receive sample from the collection device, an overflow reservoir in fluid communication with the decoupling zone to accommodate any sample that does not fit into the decoupling zone; wherein the overflow reservoir is configured to ensure pressure within the module can be managed. A cartridge comprising a sample management module is also provided.
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公开(公告)号：US20230358775A1
公开(公告)日：2023-11-09
申请号：US17786435
申请日：2020-12-18
Applicant: Vidya Holdings Ltd
Inventor： Stefan Leo Van Workum , Vladimir Alexander Turek , Marko Dorrestijn , David R. Klug
CPC classification number: G01N35/025 , G01N35/0092 , G01N35/00732 , B01L3/502 , G01N2035/0096 , G01N2035/00356 , G01N2035/00306 , B01L2300/023 , B01L2200/147 , B01L2200/04 , B01L2200/16
Abstract: A storage and incubation device is provided. The device is configured to accommodate a plurality of assay chips, each assay chip including a unique identifier. The device comprises: a plurality of berths each sized to accommodate an assay chip; a communication module configured to receive information about the identifier of each assay chip; a clock timer configured to monitor the timing of the assay within each assay chip; a completion module to manage each assay chip when the assay is complete.
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公开(公告)号：US20230280338A1
公开(公告)日：2023-09-07
申请号：US18015463
申请日：2021-07-09
Applicant: VIDYA HOLDINGS LTD
Inventor： Marko Dorrestijn , David R. Klug , Vladimir Turek , Stefan Leo Van Workum
IPC: G01N33/543 , G01N21/63
CPC classification number: G01N33/54373 , G01N21/63 , G01N2201/121
Abstract: An apparatus for creating and correcting a two dimensional intensity map of one or more assay spots in a detection zone is provided. The apparatus comprising, a locator for affirming the location of the detection zone; a total internal reflection excitation device comprising a light source for illuminating the one or more assay spots in the detection zone; a detector configured to receive light that is emitted, reflected or scattered from the one or more assay spots and to create a two dimensional intensity map of the one or more assay spots comprising a two dimensional array of quantitative pixel values; and a processor configured to correct the intensity map to remove noise through analysis of corresponding pixel values from an earlier intensity map; wherein the analysis includes curve fitting.
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Patent Agency Ranking
公开(公告)号：US20220146505A1
公开(公告)日：2022-05-12
申请号：US17435376
申请日：2020-02-28
Applicant: Vidya Holdings Ltd
Inventor： Marko Dorrestijn , David R. Klug , Shao-Ju LU , Callum Robertson Smith , Stefan Leo Van Workum , Vlad Turek
IPC: G01N33/543 , B01L3/00 , G01N21/64
Abstract: An assay cartridge for detecting a target component in a liquid sample is provided. The cartridge comprises: a sample collection unit configured to introduce the liquid sample into the cartridge; a fluid pathway commencing at its proximal end at the sample collection unit and extending distally through the cartridge including: one or more capture components immobilised within the fluid pathway; one or more detection reagents provided within the diffusion distance of the capture components.
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公开(公告)号：US20220143597A1
公开(公告)日：2022-05-12
申请号：US17435375
申请日：2020-02-28
Applicant: Vidya Holdings Ltd
Inventor： Marko Dorrestijn , David R. Klug , Shao-Ju LU , Callum Robertson Smith , Stefan Leo Van Workum , Vlad Turek
IPC: B01L3/00
Abstract: An assay cartridge for detecting a target component in a liquid sample is provided. The cartridge comprises: a sample collection unit configured to introduce the liquid sample into the cartridge; a fluid pathway commencing at its proximal end at the sample collection unit and extending distally through the cartridge including: one or more capture components immobilised within the fluid pathway; one or more detection reagents provided proximally of or level with the capture components each contained within a liquid droplet.
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公开(公告)号：US20230346357A1
公开(公告)日：2023-11-02
申请号：US18021981
申请日：2021-08-20
Applicant: VIDYA HOLDINGS LTD
Inventor： Marko Dorrestijn , David R. Klug , Vladimir Turek , Stefan Leo Van Workum
CPC classification number: A61B10/0051 , G01N1/4077 , G01N2001/4088
Abstract: A combined sample collection and filtration device is provided for collecting and filtering a fluid sample. The device comprises: a sample collection location; a filter module for removing particulate matter from the fluid sample; the filter module having bubble point and a burst pressure; and one or more voids in communication with the sample collection location for accommodating sample during pressurisation such that the pressure within the device remains below the bubble point and the burst pressure of the filter module.
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公开(公告)号：US20230021366A1
公开(公告)日：2023-01-26
申请号：US17786469
申请日：2020-12-18
Applicant: Vidya Holdings Ltd
Inventor： Stefan Leo Van Workum , Vladimir Alexander Turek , Marko Dorrestijn , David R. Klug
IPC: B01L3/00 , G01N33/543 , G01N21/64
Abstract: An apparatus (1) for detecting the presence and/or the quantity of a target component in a biological fluid in an integrated assay cartridge (52) of predetermined configuration, the assay cartridge comprising a capture component (22) at a predetermined location in the assay cartridge, the apparatus comprising: a detector (12)for detecting the amount of light scattered, transmitted or emitted by the sample to provide an indication of the presence and/or the quantity of the target component within the sample; three location positions (30), the three positions defining a location along the optical path of the detector on which to locate the cartridge of a predetermined size; wherein location positions are configured such that the capture component of the assay cartridge is located, in use, at the focal plane of the detector. Measures to ensure quality control may also be provided.
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公开(公告)号：US20220146425A1
公开(公告)日：2022-05-12
申请号：US17435372
申请日：2020-02-28
Applicant: Vidya Holdings Ltd
Inventor： Stefan Leo Van Workum , Callum Robertson Smith , Marko Dorrestijn , David R. Klug
Abstract: An assay cartridge for detecting a target component in a fluid is provided. The assay cartridge including an optical element comprising: a light pathway comprising an input surface, reflective surface and output surface configured to enable light to enter, reflect and create an evanescent field in the vicinity of the reflective surface and exit the element; a plurality of capture components deposited on the reflective surface in the vicinity of the evanescent field; and a transmission surface configured to enable emissions from the evanescent field to exit the element; wherein the assay cartridge is a single use cartridge.
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