Invention Patent
AT554071T
未知
- Patent Title:
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Application No.: AT00942823Application Date: 2000-06-15
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Publication No.: AT554071TPublication Date: 2012-05-15
- Inventor: ALLEN MICHAEL , PREMCHANDRAN RAMIYA , CHANG SOU-JEN , CONDON STEPHEN , DEMATTEI JOHN , KING STEVEN , KOLACZKOWSKI LAWRENCE , MANNA SUKUMAR , NICHOLS PAUL J , PATEL HEMANT , PATEL SUBHASH , PLATA DANIEL , STONER ERIC , TIEN JIEN-HEH , WITTENBERGER STEVEN
- Applicant: ABBOTT LAB
- Assignee: ABBOTT LAB
- Current Assignee: ABBOTT LAB
- Priority: US14104299 1999-06-24
- Main IPC: C07D215/14
- IPC: C07D215/14 ; C07C33/03 ; C07C43/303 ; C07C47/22 ; C07C68/06 ; C07C69/96 ; C07C269/06 ; C07C271/12 ; C07D215/18 ; C07D401/12 ; C07H17/08
Abstract:
The invention relates to a process for preparing carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or a substrate that can be reduced to obtain the same. €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒR 1 -CH=CHCH 2 OC(O)-X-R 2 €ƒ€ƒ€ƒ€ƒ€ƒ(I)
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