Invention Grant
- Patent Title: Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue
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Application No.: US15555818Application Date: 2016-03-07
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Publication No.: US11295941B2Publication Date: 2022-04-05
- Inventor: Emrys Jones , Steven Derek Pringle , Zoltan Takats
- Applicant: Micromass UK Limited
- Applicant Address: GB Wilmslow
- Assignee: Micromass UK Limited
- Current Assignee: Micromass UK Limited
- Current Assignee Address: GB Wilmslow
- Priority: GB1503863 20150306,GB1503864 20150306,GB1503867 20150306,GB1503876 20150306,GB1503877 20150306,GB1503878 20150306,GB1503879 20150306,GB1516003 20150909,GB1518369 20151016
- International Application: PCT/GB2016/050626 WO 20160307
- International Announcement: WO2016/142696 WO 20160915
- Main IPC: H01J49/04
- IPC: H01J49/04 ; A61B10/02 ; A61B17/32 ; A61B18/00 ; A61B18/14 ; A61B18/20 ; G01N3/00 ; G01N9/00 ; G01N33/68 ; H01J49/00 ; H01J49/06 ; H01J49/16 ; A61B90/13 ; A61B1/04 ; A61B1/273 ; A61B5/00 ; A61B5/01 ; A61B5/0507 ; A61B5/055 ; A61B6/03 ; A61B8/13 ; A61B10/00 ; A61B17/00 ; A61B18/04 ; A61B18/18 ; A61F13/38 ; C12Q1/02 ; C12Q1/04 ; C12Q1/18 ; C12Q1/24 ; G01N1/22 ; G01N27/622 ; G01N27/624 ; G01N30/72 ; G01N33/487 ; G01N33/92 ; H01J49/02 ; H01J49/10 ; H01J49/14 ; H01J49/24 ; H01J49/26 ; G16B20/00 ; G16H10/40 ; G16H15/00 ; G16H50/20 ; A61B1/00 ; A61B1/31 ; A61B5/145
Abstract:
A method of ion imaging is disclosed that includes automatically sampling a plurality of different locations on a sample using a front device which is arranged and adapted to generate aerosol, smoke or vapour from the sample. Mass spectral data and/or ion mobility data corresponding to each location is obtained and the obtained mass spectral data and/or ion mobility data is used to construct, train or improved a sample classification model.
Public/Granted literature
- US11367605B2 Ambient ionization mass spectrometry imaging platform for direct mapping from bulk tissue Public/Granted day:2022-06-21
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