Invention Grant
- Patent Title: Combination therapies for inhibition of TTK protein kinase
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Application No.: US16635320Application Date: 2018-08-01
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Publication No.: US11766437B2Publication Date: 2023-09-26
- Inventor: Mark Robert Bray , Jacqueline M. Mason , Tak W. Mak , Graham Fletcher
- Applicant: UNIVERSITY HEALTH NETWORK
- Applicant Address: CA Toronto
- Assignee: UNIVERSITY HEALTH NETWORK
- Current Assignee: UNIVERSITY HEALTH NETWORK
- Current Assignee Address: CA Toronto
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- Priority: WO TCA2017050920 2018.08.01
- International Application: PCT/CA2018/050936 2018.08.01
- International Announcement: WO2019/023799A 2019.02.07
- Date entered country: 2020-01-30
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61P35/00 ; A61K39/395

Abstract:
Provided herein are methods of treating cancer using an effective amount of a compound represented by the formula: (I) or a pharmaceutically acceptable salt thereof and an effective amount of an immune checkpoint inhibitor. Also provided are compositions comprising the same compound represented by the formula shown above or a pharmaceutically acceptable salt thereof and an immune checkpoint inhibitor.
Public/Granted literature
- US20200230144A1 COMBINATION THERAPIES FOR INHIBITION OF TTK PROTEIN KINASE Public/Granted day:2020-07-23
Information query
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