公开(公告)号：WO9719702A3

公开(公告)日：1997-08-28

申请号：PCT/EP9605062

申请日：1996-11-18

Applicant: BASF AG ,  BREITENBACH JOERG ,  SANNER AXEL ,  DENZINGER WALTER ,  LANG SIEGFRIED

Inventor： BREITENBACH JOERG ,  SANNER AXEL ,  DENZINGER WALTER ,  LANG SIEGFRIED

IPC: A61K47/48 ,  A01N59/12 ,  A61K31/00 ,  A61K31/755 ,  A61K31/787 ,  A61P1/00 ,  A61P1/12 ,  A61P31/00 ,  A61P31/04 ,  C08F8/18 ,  C08F8/20 ,  C08F8/22 ,  C08F26/06 ,  C08F226/06 ,  C08K3/02 ,  C08L39/04

CPC classification number: C08F226/06 ,  C08F8/22 ,  C08F26/06

Abstract: The invention concerns powdery complexes comprising iodine and a crosslinked polymer based on N-vinyl compounds and obtained by the dry heating of iodine and a polymer obtained by polymerizing monovinyl compounds (monomers A), of which the vinyl group is bonded to an N-atom of a nitrogenous heterocyclic ring, in the presence of between 0.5 and 10 wt %, relative to the monomers (A), of a compound (B) of general formula (I), A standing for -CH- or an N-atom and n being 2 or 3. The complexes are suitable for producing anti-diarrhoeal agents.

Abstract translation: 可以通过干燥加热碘和聚合物获得碘粉末形式和基于N-乙烯基化合物的交联聚合物的复合物，该聚合物是通过使乙烯基结合到氮的氮原子上的单乙烯基化合物（单体A） 基于单体（A），式（I）化合物（B）的0.5〜10重量％的存在下，其中A为-CH-或氮原子，n为2 或3.复合物适用于产生止泻药。

公开(公告)号：CA2268077C

公开(公告)日：2007-12-18

申请号：CA2268077

申请日：1997-10-07

Applicant: BASF AG

Inventor： KRATZ DETLEF ,  BREITENBACH JORG ,  LANG SIEGFRIED

IPC: C07D223/10 ,  C07D413/06 ,  A61K8/49 ,  A61K9/00 ,  A61K9/08 ,  A61K31/42 ,  A61K31/445 ,  A61K31/535 ,  A61K31/55 ,  A61K47/06 ,  A61K47/16 ,  A61K47/22 ,  A61Q19/00 ,  C07D207/26 ,  C07D207/263 ,  C07D207/267 ,  C07D207/27 ,  C07D211/40 ,  C07D211/76 ,  C07D227/087 ,  C07D263/18 ,  C07D265/28 ,  C07D265/32 ,  C07D401/06 ,  C07D403/06

Abstract: The present invention relates to a 1,3-bis-(N-lactamyl)propane of general formula (I), wherein radicals R1, R2, R3, R4, R5 and R6 independently stand for hydrogen, alkyl, cycloalkyl, aryl or aralkyl and at least one of said radicals does not stand for hydrogen, (NLac) and (NLac') are the same or different and stand for N-lactamyl radicals. The invention also relates to the use of said substances as a solvent in pharmaceutical and cosmetic agents. Disclosed are novel compounds of formula (I), wherein R1 and methyl and R2-R6 stand for hydrogen.

公开(公告)号：DK0863767T3

公开(公告)日：2002-07-01

申请号：DK96939084

申请日：1996-11-18

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  SANNER AXEL ,  DENZINGER WALTER ,  LANG SIEGFRIED

IPC: A61K47/48 ,  A01N59/12 ,  A61K31/00 ,  A61K31/755 ,  A61K31/787 ,  A61P1/00 ,  A61P1/12 ,  A61P31/00 ,  A61P31/04 ,  C08F8/18 ,  C08F8/20 ,  C08F8/22 ,  C08F26/06 ,  C08F226/06 ,  C08K3/02 ,  C08L39/04

Abstract: Complexes in powder form of iodine and a crosslinked polymer based on N-vinyl compounds are obtainable by dry heating of iodine and a polymer which is obtained by polymerization of monovinyl compounds (monomers A) whose vinyl group is bonded to a nitrogen atom of a nitrogen-containing heterocycle, in the presence of from 0.5 to 10% by weight, based on the monomers (A), of a compound (B) of the formula I;where A is -CH- or a nitrogen atom, and n is 2 or 3. The complexes are suitable for producing antidiarrheals.

公开(公告)号：AU7212096A

公开(公告)日：1997-04-17

申请号：AU7212096

申请日：1996-09-20

Applicant: BASF AG

Inventor： DRALLE-VOSS GABRIELE ,  STOSSER MICHAEL ,  LANG SIEGFRIED ,  SAUPE THOMAS ,  ZIPPLIES MATTHIAS

IPC: A61K47/44 ,  C07C67/56 ,  C07C69/30 ,  C11B3/10 ,  C11C3/00

Abstract: PCT No. PCT/EP96/04116 Sec. 371 Date Mar. 24, 1998 Sec. 102(e) Date Mar. 24, 1998 PCT Filed Sep. 20, 1996 PCT Pub. No. WO97/12017 PCT Pub. Date Apr. 3, 1997A process for purifying alkoxylated fats by treatment with a solid substance, wherein a mixture of aluminum oxide and a silicate is employed as solid substance.

公开(公告)号：FI87887C

公开(公告)日：1993-03-10

申请号：FI871539

申请日：1987-04-08

Applicant: BASF AG

Inventor： GOERTZ HANS-HELMUT ,  KLIMESCH ROGER GUENTHER ,  LAEMMERHIRT KLAUS ,  LANG SIEGFRIED ,  SANNER AXEL ,  SPENGLER REINHARD

IPC: A61J3/06 ,  A61K9/20 ,  A61K9/22 ,  A61K9/26 ,  A61K47/32 ,  A61K47/00 ,  A61J3/00 ,  A61K31/47

公开(公告)号：CA1273744A

公开(公告)日：1990-09-04

申请号：CA516900

申请日：1986-08-27

Applicant: BASF AG

Inventor： NUBER ADOLF ,  LANG SIEGFRIED ,  SANNER AXEL ,  SCHROEDER GERD

IPC: C08F4/00 ,  C08F4/28 ,  C08F4/34 ,  C08F26/00 ,  C08F26/10

Abstract: Polyvinylpyrrolidone having a Fikentscher K value of from 14 to 95 is prepared at from 50 to 95.degree.C in aqueous solution with hydrogen peroxide as starter, the solution being maintained at pH 7-11 by means of NaOH, KOH, their carbonates or bicarbonates.

公开(公告)号：AU587897B2

公开(公告)日：1989-08-31

申请号：AU7141387

申请日：1987-04-10

Applicant: BASF AG

Inventor： GOERTZ HANS-HELMUT ,  KLIMESCH ROGER GUENTHER ,  LAEMMERHIRT KLAUS ,  LANG SIEGFRIED ,  SANNER AXEL ,  SPENGLER REINHARD

IPC: A61K47/32 ,  A61J3/06 ,  A61K9/20 ,  A61K9/22 ,  A61K9/26 ,  A61K47/00

Abstract: Process for the preparation of solid pharmaceutical forms by mixing one or more pharmaceutical active compounds with one or more fusible, pharmacologically tolerated binders and, if required, other conventional pharmaceutical auxiliaries, at from 50 DEG to 180 DEG C., and subjecting the mixture to injection molding or extrusion and shaping, wherein the fusible binder used is a NVP polymer which contains not less than 20% by weight of NVP as copolymerized units, and, where they are present, all of whose comonomers contain nitrogen and/or oxygen.

公开(公告)号：HU196132B

公开(公告)日：1988-10-28

申请号：HU161787

申请日：1987-04-10

Applicant: BASF AG

Inventor： GOERTZ HANS-HELMUT ,  KLIMESCH ROGER G ,  LAEMMERHIRT KLAUS ,  LANG SIEGFRIED ,  SANNER AXEL ,  SPENGLER REINHARD

IPC: A61J3/06 ,  A61K47/32 ,  A61K9/20 ,  A61K9/22 ,  A61K9/26 ,  A61K47/00

Abstract: Process for the preparation of solid pharmaceutical forms by mixing one or more pharmaceutical active compounds with one or more fusible, pharmacologically tolerated binders and, if required, other conventional pharmaceutical auxiliaries, at from 50 DEG to 180 DEG C., and subjecting the mixture to injection molding or extrusion and shaping, wherein the fusible binder used is a NVP polymer which contains not less than 20% by weight of NVP as copolymerized units, and, where they are present, all of whose comonomers contain nitrogen and/or oxygen.

公开(公告)号：AU7141387A

公开(公告)日：1987-10-15

申请号：AU7141387

申请日：1987-04-10

Applicant: BASF AG

Inventor： GOERTZ HANS-HELMUT ,  KLIMESCH ROGER GUENTHER ,  LAEMMERHIRT KLAUS ,  LANG SIEGFRIED ,  SANNER AXEL ,  SPENGLER REINHARD

IPC: A61K47/32 ,  A61J3/06 ,  A61K9/20 ,  A61K9/22 ,  A61K9/26 ,  A61K47/00

Abstract: Process for the preparation of solid pharmaceutical forms by mixing one or more pharmaceutical active compounds with one or more fusible, pharmacologically tolerated binders and, if required, other conventional pharmaceutical auxiliaries, at from 50 DEG to 180 DEG C., and subjecting the mixture to injection molding or extrusion and shaping, wherein the fusible binder used is a NVP polymer which contains not less than 20% by weight of NVP as copolymerized units, and, where they are present, all of whose comonomers contain nitrogen and/or oxygen.

公开(公告)号：NO871513D0

公开(公告)日：1987-04-10

申请号：NO871513

申请日：1987-04-10

Applicant: BASF AG

Inventor： GOERTZ HANS-HELMUT ,  KLIMESCH ROGER GUENTHER ,  LAEMMERHIRT KLAUS ,  LANG SIEGFRIED ,  SANNER AXEL ,  SPENGLER REINHARD

IPC: A61J3/06 ,  A61K47/32 ,  A61K9/20 ,  A61K9/22 ,  A61K9/26 ,  A61K47/00 ,  A61J

Abstract: Process for the preparation of solid pharmaceutical forms by mixing one or more pharmaceutical active compounds with one or more fusible, pharmacologically tolerated binders and, if required, other conventional pharmaceutical auxiliaries, at from 50 DEG to 180 DEG C., and subjecting the mixture to injection molding or extrusion and shaping, wherein the fusible binder used is a NVP polymer which contains not less than 20% by weight of NVP as copolymerized units, and, where they are present, all of whose comonomers contain nitrogen and/or oxygen.