PHARMACEUTICAL FORMULATION FOR PRODUCING RAPIDLY DISINTEGRATING TABLETS
    6.
    发明申请
    PHARMACEUTICAL FORMULATION FOR PRODUCING RAPIDLY DISINTEGRATING TABLETS 审中-公开
    药物制剂FOR FAST崩解片剂的制造

    公开(公告)号:WO2007071581A3

    公开(公告)日:2008-01-10

    申请号:PCT/EP2006069515

    申请日:2006-12-11

    CPC classification number: A61K9/0056 A61K9/2018

    Abstract: The invention relates to a pharmaceutical formulation in the form of agglomerates containing a) 60 - 97 % by weight of sugar or sugar alcohols, b) 1 - 25 % by weight of cross-linked polyvinylpyrrolidone, c) 1 - 15 % by weight of water-insoluble, film-forming polymers, d) 0 - 15 % by weight of water-soluble polymers, and e) 0 - 15 % by weight of other pharmaceutically suitable adjuvants, the sum of components a) to e) adding up to 100 % by weight.

    Abstract translation: 在含有糖或糖醇的)60-97重量%的聚集体形式的药物制剂,b)中1 - 25重量%的交联聚乙烯吡咯烷酮,C)1 - 15重量%的水不溶性,成膜聚合物d)0 - 15 重量的水溶性聚合物的.-%,和e)0 - 15重量%的其它药学上常用的赋形剂,其中组分的总和a)至e)为100重量%(重量)。

    10.
    发明专利
    未知

    公开(公告)号:FI118048B

    公开(公告)日:2007-06-15

    申请号:FI972678

    申请日:1997-06-19

    Applicant: BASF AG

    Abstract: PCT No. PCT/EP95/04934 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 13, 1995 PCT Pub. No. WO96/20155 PCT Pub. Date Jul. 4, 1996Process for preparing solid, free-flowing water-soluble salts of aryloxy-C1-C4-alkanecarboxylic acids by reacting the aryloxy-C1-C4-alkanecarboxylic acids with a salt-forming base, the salt formation taking place in the melt in the presence or absence of an entraining agent suitable for the azeotropic removal of water or in solution in the presence of an entraining agent suitable for the azeotropic removal of water and, if appropriate, removing the entraining agent from the reaction mixture during the reaction or subsequently and then isolating the solid salts in a customary manner.

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