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公开(公告)号：WO0015292A3
公开(公告)日：2000-07-20
申请号：PCT/US9920400
申请日：1999-09-07
Applicant: BAXTER INT
Inventor： FOWLES THOMAS A , WEINBERG ROBERT J , PROGAR THOMAS J
CPC classification number: A61J1/2089 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , A61J1/2013 , A61J1/2051
Abstract: A connector device (10) is disclosed for establishing fluid communication between a diluent container (12) having sidewalls and a drug vial (14). The connector (10) has a piercing member (51) having a first end (52) and a second end (53) and a central fluid pathway (54). The piercing member (51) is mounted to the liquid container (12) and has fluid accessing portions hermetically sealed from an outside environment. A vial receiving chamber is associated with the piercing member (51) and is dimensioned to connect to the vial (14). The vial (14) may be selectively attached to the device (10) without piercing the closure (22) of the vial (14) and without breaching the hermetic seal of the fluid accessing portions of the piercing member (51). Means are provided for connecting the vial receiving chamber to the liquid container (12). The device (10) is movable from an inactivated position, where the piercing member (51) is outside the sidewalls and no fluid flows between the liquid container (12) and the drug vial (14), to an activated position, where fluid flows through the fluid pathway (54) between the liquid container (12) and the drug vial (14). The device (10) is movable from the inactivated position to the activated position by a force applied to the device (10) outside the liquid container (12).
Abstract translation: 公开了用于建立具有侧壁的稀释剂容器（12）和药物瓶（14）之间的流体连通的连接器装置（10）。 连接器（10）具有穿刺构件（51），其具有第一端（52）和第二端（53）以及中心流体路径（54）。 刺穿构件（51）安装在液体容器（12）上并具有从外部环境密封的流体通路部分。 小瓶容纳室与刺穿构件（51）相关联，并且其尺寸被设计成连接到小瓶（14）。 小瓶（14）可以选择性地附接到装置（10）而不刺穿小瓶（14）的封闭件（22），而不会破坏穿孔构件（51）的流体进入部分的气密密封。 提供了用于将小瓶容纳室连接到液体容器（12）的装置。 装置（10）可从非活动位置移动，其中刺穿构件（51）在侧壁外部，并且液体容器（12）和药物瓶（14）之间没有流体流动到流体流动的启动位置 通过液体容器（12）和药物瓶（14）之间的流体通道（54）。 装置（10）可以通过施加到液体容器（12）外部的装置（10）的力从非活动位置移动到致动位置。
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公开(公告)号：EP0660690A4
公开(公告)日：1995-09-13
申请号：EP95904345
申请日：1994-04-08
Applicant: BAXTER INT
Inventor： FOWLES THOMAS A , FOTIS NICK , ELLER CHARLES , GORMAN BRIAN J , HOEKWATER MARK A
CPC classification number: A61M5/1409
Abstract: An adapter (100, 200) for interconnecting in fluid communication a first connection site (27) and a beneficial agent container having a closure. The adapter includes a plate having first and second connection site sides (104). A wall (110) extends from the plate (108) from the second connection site side and is constructed to surround only the closure. This allows containers having varying sized bodies to be received. A cannula structure (120, 130) is rigidly secured in the plate and defining a flow path extending through the plate. The adapter can be provided in assembly with the beneficial agent contained or in a drug delivery system.
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公开(公告)号：EP0563357A4
公开(公告)日：1995-01-25
申请号：EP92922042
申请日：1992-09-25
Applicant: BAXTER INT
Inventor： HOEKWATER MARK , NORDQUIST JEFFREY S , FOWLES THOMAS A , SERTIC JAMES , GORMAN BRIAN J RT
CPC classification number: A61J1/2089 , A61J1/201 , A61J1/2051 , A61J1/2065 , A61M5/1409 , Y10S285/921 , Y10S604/905
Abstract: A drug delivery device is provided comprising a cartridge body (12) including an upper portion (14) defining a vial receiving area and terminating in a wall (20), the cartridge body (12) including a cannula (22) extending from the wall. A vial (40) including a beneficial agent is coupled by a retaining member (50) to the cartridge body (12) in an inactivated position. The retaining member (50) allows the vial (40) to move to an activated position. The retaining member (50) including an outer member (52) and an inner member (54), the inner member (54) separating from portions of the outer member (52) as the vial (40) moves from the inactivated position to the activated position.
Abstract translation: 本发明提供了一种药物输送装置，其包括：药筒主体（12），其包括限定药瓶容纳区域并终止于壁（20）的上部部分（14），药筒主体（12）包括插管（22） 。 包括有益药剂的小瓶（40）通过保持构件（50）联接到处于非激活位置的仓体（12）。 保持构件（50）允许小瓶（40）移动到启动位置。 所述保持构件（50）包括外部构件（52）和内部构件（54），所述内部构件（54）在所述瓶（40）从所述非致动位置移动到所述外部构件 激活位置。
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公开(公告)号：EP0606450A4
公开(公告)日：1996-06-05
申请号：EP93917203
申请日：1993-07-14
Applicant: BAXTER INT
Inventor： BANCSI JOSEPH A , ELLER CHARLES , FOWLES THOMAS A , GORMAN BRIAN J , HEBRON TERRENCE J , JERSILD CHARLES , JESS DONALD A , WONG JOSEPH C T , WOOD RAY W
CPC classification number: A61M5/1409 , Y10S604/905
Abstract: The present invention provides an improved cannula (22) that can be used to reconstitute powdered drugs in a drug delivery system. Furthermore, the present invention provides a cannula (22) and drug delivery system incorporating same. To this end, the present invention provides a cannula structure for use in a reconstitution of a powdered drug comprising a cannula (22) having a first end (26) and a second end (28), and defining a channel in an interior thereof between the first and second ends (26, 28). The first end (26) is closed and includes a member (27) for piercing a septum (42). The cannula (22) includes at least two slots (50a, 50b) providing fluid communication between the channel and an exterior of the cannula (22). The slots (50a, 50b) are located in juxtaposition to the first end (26) and have a width, as measured along a length of the cannula (22), that is less than a length, as measured around the cannula (22). The slots (50a, 50b) also have a minimum projected area equal to or greater than the cross-sectional area of the channel.
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公开(公告)号：EP0662851A4
公开(公告)日：1995-11-29
申请号：EP94921168
申请日：1994-04-08
Applicant: BAXTER INT
Inventor： FOWLES THOMAS A , ROLLINS RICHARD A , HOEKWATER MARK A
CPC classification number: A61J1/2089 , A61J1/201 , A61J1/2013 , A61J1/2065 , A61M5/1409
Abstract: An improved drug delivery system and method for reconstituting drugs. The system allows the delivery of a medicament from a drug vial (40) directly into an intravenous line to a patient. The system provides a method and apparatus that insures that the drug vial is properly pierced and the vial is locked into an activated position when it is desired to use same. To this end, a vial retaining member (50) for coupling the vial to a cartridge (12) including a cannula (22) is provided. The retaining member includes a cannula centering member (64) extending from an end thereof.
Abstract translation: 提供了改进的药物递送系统和重建药物的方法。 该系统允许将药物从药物瓶（40）直接输送到患者的静脉内管线中。 该系统提供了一种确保药瓶（40）被适当刺穿并且当需要使用该药瓶时将小瓶（40）锁定到激活位置的方法和装置。 为此，提供了用于将小瓶（40）连接到包括插管（22）的盒（12）的小瓶保持构件（50）。 保持构件（50）包括从其端部延伸的套管对中构件。
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Patent Agency Ranking
公开(公告)号：AT493962T
公开(公告)日：2011-01-15
申请号：AT04075267
申请日：1999-09-07
Applicant: BAXTER INT
Inventor： WEINBERG ROBERT J , FOWLES THOMAS A
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公开(公告)号：DK1415636T3
公开(公告)日：2009-06-08
申请号：DK04075268
申请日：1999-09-07
Applicant: BAXTER INT
Inventor： WEINBERG ROBERT J , FOWLES THOMAS A
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公开(公告)号：CA2279254C
公开(公告)日：2008-09-23
申请号：CA2279254
申请日：1998-11-19
Applicant: BAXTER INT
Inventor： FULLER CRAIG A , FOWLES THOMAS A , PROGAR THOMAS J , WEINBERG ROBERT J
Abstract: The present invention provides a connector device (10) for establishing fluid communication between a first container (12) and a second container (14). The device (10) has a first sleeve member (30) having a first end (40) and a second end (42), the first sleeve member (30) having at the first end (40) a first attaching member adapted to attach to the first container (12). The device (10) further has a second sleeve member (32) having a first end (80) and a second end (82), the second sleeve member (32) being associated with the first sleeve member (30) and movable with respect thereto from an inactivated position to an activated position, the second sleeve member (32) having at the second end (82) a second attaching member adapted to attach the second sleeve member (32) to the second container (14). First and second piercing members (34) project from one of the first and second sleeve members (30, 32) for providing a fluid flow path from the first container (12) to the second container (14), and the first and second piercing members (34) are independently hermetically sealed.
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公开(公告)号：CA2546842A1
公开(公告)日：2005-07-21
申请号：CA2546842
申请日：2004-12-01
Applicant: BAXTER INT
Inventor： WEINBERG ROBERT J , FOWLES THOMAS A
Abstract: A reconstitution assembly includes: a flexible bag containing a diluent; a drug vial containing a drug; a reconstitution device further comprising: a first sleeve connected to the first container; a second sleeve connected to the second container, the second sleeve being associated with the first sleeve and movable axially with respect thereto from an inactivated position to an activated position; a piercing member positioned in the sleeves, the piercing member providing a fluid pathway between the bag and vial when the sleeves are in the activated position.
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公开(公告)号：DE69830430D1
公开(公告)日：2005-07-07
申请号：DE69830430
申请日：1998-11-19
Applicant: BAXTER INT
Inventor： FULLER CRAIG A , PROGAR THOMAS J , WEINBERG ROBERT J , FOWLES THOMAS A
Abstract: A connector device (10) for establishing fluid communication between a first container (12) and a second container (14) is described. The device comprises a first sleeve member (30) having a first end (40) and a second end (42) and a means at the first end for attaching to the first container. The device also comprises a second sleeve member (32) having a first end (80) and a second end (82). The second sleeve member is associated with the first sleeve member and movable in an axial direction with respect thereto from an inactivated position to an activated position. The second sleeve member also comprises at the second end a means for fixedly attaching to the second container. The device is provided with first (34b) and second (34a) piercing members projecting from one of the first and second sleeve members for providing fluid flow from the first container to the second container. A method of connecting a reconstitution device (10) to a drug container (14) having a top and a closure (24, 26) is also described as is a method of reconstituting a drug contained in a second container (14) with a diluent contained in a first container (12).
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