-
公开(公告)号：EP0583050A3
公开(公告)日：1994-10-05
申请号：EP93303308.6
申请日：1993-04-28
Applicant: AMGEN INC. , YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Wen, Duanzhi , Peles, Elior , Yarden, Yosef
CPC classification number: C07K14/4756 , A61K38/00
Abstract: Recombinant neu receptor stimulating factor, analogs of the factor, DNA sequences encoding the same, and methods of production are disclosed. Pharmaceutical compositions and methods of treating disorders involving neu receptor expression are also described.
-
92.发明公开ENZYMATICALLY-PRODUCED DIMERIC IL-2 AND A NERVE-DERIVED TRANSGLUTAMINASE ENZYME FOR ITS PREPARATION 失效酶法MADE二聚体IL-2和1名神经WON谷氨酰胺转胺酶所作的介绍的。
公开(公告)号：EP0610475A1
公开(公告)日：1994-08-17
申请号：EP93918528.0
申请日：1993-07-30
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： SCHWARTZ, Michal , EITAN, Shoshana
CPC classification number: C12N9/1044 , A61K38/00 , C07K14/55
Abstract: L'invention se rapporte à une nouvelle enzyme, la transglutaminase, derivée du nerf optique et qui transforme l'IL-2 immune dérivée en IL-2 dimère ayant une activité cytotoxique sur les oligodendrocytes. La transglutaminase dérivée du nerf optique et l'IL-2 dimère de mammifères, tels que l'homme, sont toutes les deux utilisées comme ingrédients actifs dans des compositions pharmaceutiques afin d'introduire et de faciliter la régénération des nerfs lésés du système nerveux central des mammifères.
-
93.发明公开METHODS AND COMPOSITIONS FOR CANCER THERAPY AND FOR PROGNOSTICATING RESPONSES TO CANCER THERAPY 失效方法和用于癌症治疗的组合物和反应，这种治疗方法VORHERRAGBARKEIT。
公开(公告)号：EP0554441A1
公开(公告)日：1993-08-11
申请号：EP92918871.0
申请日：1992-08-21
Inventor： BACUS, Sarah, S. , YARDEN, Yosef , SELA, Michael
CPC classification number: G01N33/5011 , A61K38/00 , A61K47/6855 , C07K16/3015 , C07K16/32 , C07K2317/73
Abstract: Procédé de détermination de l'efficacité d'un agent thérapeutique, in vitro, utilisé dans le traitement d'un cancer caractérisé par l'expression ou la surexpression d'un produit oncogène. Le procédé est notamment utile pour déterminer l'efficacité d'agents thérapeutiques présentant une affinité de liaison pour le cancer, exprimant HER-2/neu. L'invention concerne également les anticorps monoclonaux N24, N28 et N29 identifiés par ce procédé. On peut utiliser un ou plusieurs de ces anticorps comme agent thérapeutique dans le traitement des cancers du sein, de l'estomac, des ovaires ou des glandes salivaires.
-
公开(公告)号：EP0512528A3
公开(公告)日：1993-07-21
申请号：EP92107685.7
申请日：1992-05-07
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Wallach, David , Aderka, Dan , Engelmann, Hartmut
IPC: A61K37/02
CPC classification number: A61K38/1793
Abstract: Tumor Necrosis Factor Binding Proteins (TBPs) are useful in the treatment of autoimmune diseases and graft-versus-host reactions.
-
公开(公告)号：EP0466140A3
公开(公告)日：1993-03-24
申请号：EP91111511.1
申请日：1991-07-10
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Breskin, Amos , Chechik, Rachel , Dafni, Ehud
CPC classification number: G01T1/28 , G01N27/44717 , H01J47/02
Abstract: Apparatus for digital imaging including at least one electron multiplier (16) arranged to receive beta radiation from a sample (12), apparatus for collimating the beta radiation without totally blocking all radiation from any location within a given region of interest on the sample (12), and readout electrodes operative in response to electrons from the electron multiplier (16) to provide a first output indication of the incidence and location of beta radiation from the sample (12).
-
Patent Agency Ranking96.发明授权Cell membrane proteins, compositions containing them and procedure for their preparation 失效细胞膜蛋白，包含它们的组合物及其制备方法
公开(公告)号：EP0261648B1
公开(公告)日：1992-12-09
申请号：EP87113856.6
申请日：1987-09-22
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Cohen, Irun Robert , Shinitzky, Meir
CPC classification number: A61K39/0008 , A61K35/17 , A61K2039/5158 , C12N5/0636 , C12N2521/00
Abstract: Compositions for the prevention and treatment of autoimmune diseases are provided which comprise as an active ingredient membrane material shed from autoimmune T lymphocytes, or activated T lymphocytes which are treated by a pressure application and release process. There is also provided processes for obtaining such active materials and for preparing pharmaceutical compositions containing them.
-
公开(公告)号：EP0426785A4
公开(公告)日：1991-11-13
申请号：EP90905295
申请日：1990-03-16
Inventor： MERUELO, DANIEL , LAVIE, GAD , MAZUR, YEHUDA
IPC: A61K31/047 , A61K31/12 , A61K31/122 , A61K31/13 , A61K31/19 , A61K31/215 , A61K31/22 , A61K31/505 , A61K31/70 , A61P31/12 , A61P43/00 , C07C39/12 , C07C39/17 , C07C50/36 , C07D221/18 , C07D471/04 , C07D493/04 , A61K31/00
CPC classification number: C07C39/12 , A61K31/12 , A61K31/122 , A61K31/70 , A61K2300/00
-
公开(公告)号：EP0172987B1
公开(公告)日：1991-07-17
申请号：EP85104011.3
申请日：1985-04-03
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Schwartz, Michal , Belkin, Michael
IPC: A61K35/30
-
公开(公告)号：EP0254305B1
公开(公告)日：1990-12-05
申请号：EP87110642.3
申请日：1987-07-22
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Daren, Stephen L. J. , Vofsi, David , Finkels, Aurelia
-
100.发明授权Method and compositions comprising a vitamin D derivative for the local treatment of bone fractures 失效包含维生素D衍生物用于骨折的局部治疗的方法和组合物
公开(公告)号：EP0198213B1
公开(公告)日：1990-08-08
申请号：EP86103205.0
申请日：1986-03-11
Applicant: YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD.
Inventor： Lidor, Cobi , Edelstein, Samuel , Dekel, Samuel , Meyer, Michael S.
IPC: A61L25/00
CPC classification number: A61L27/54 , A61L24/0015 , A61L2300/428 , A61L2300/45 , A61L2430/02 , A61K31/59
-
-
-
-
-
-
-
-
-
Search Results
276
records
(took 0.036 seconds)
